Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top 5 stars Hotels in San Francisco

See all 543 Hotels in San Francisco
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,885 reviews)
A strikingly beautiful, old hotel, right in the middle of everything. But the rooms clearly haven’t been updated in a long time - and the beds were some of the worst I’ve slept on in a hotel. The shower (with the mandated low-flow shower head, so not the hotel’s fault for this, really) was just a ...
  21 Feb,2018
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,090 reviews)
Nice hotel , close to everythingThis hotel close to union square and all tourist area,
  24 Feb,2018
Omni San Francisco Hotel

Omni San Francisco Hotel

500 California St, San Francisco
5.0 out of 5.0
4.7 out of 5 (3,371 reviews)
I really liked our housekeeper, Tina. She was very friendly and kept our room very clean.
  21 Feb,2018
Argonaut Hotel - a Noble House Hotel

Argonaut Hotel - a Noble House Hotel

495 Jefferson St, San Francisco
5.0 out of 5.0
4.6 out of 5 (5,724 reviews)
AwesomeIs a beautifully hotel rooms are extremely nice and well decorated. Everything is very clean
  24 Feb,2018
Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco
5.0 out of 5.0
4.6 out of 5 (400 reviews)
Great hotel staff, perfect views of bay , nice room.I would have given complete 5 stars if their sky deck was open. It was closed for maintenance but otherwise , very good hotel .
  9 Feb,2018

SG$475

SG$475
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (782 reviews)
Awesome service. Beautiful hotel. Will stay there again.
  12 Feb,2018
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

757 Market St, San Francisco
5.0 out of 5.0
4.5 out of 5 (484 reviews)
Amazing place and amazing staff.So glad we chose the four seasons.
  28 Dec,2017
The Ritz-Carlton, Half Moon Bay

The Ritz-Carlton, Half Moon Bay

1 Miramontes Point Rd, Half Moon Bay
5.0 out of 5.0
4.6 out of 5 (374 reviews)
Very nice!!I would say that in general to pay a Ritz might be luxury only, in this place it is also like that, but it's worth it, the location of the hotel and the views have no comparison and it's a beautiful i'll say that's what you're paying for besides the standards of Ritz Carlton. SPA is really good, ...
  19 Feb,2018
The St. Regis San Francisco

The St. Regis San Francisco

125 3rd St, San Francisco
5.0 out of 5.0
4.7 out of 5 (325 reviews)
No hot SPA near the swimming pool is a little disappointment for me, but everything else is just St. Regis.
  5 Feb,2018
Taj Campton Place

Taj Campton Place

340 Stockton St, San Francisco
5.0 out of 5.0
4.6 out of 5 (926 reviews)
Nice and great locationSmall, friendly, clean and excellent location. Very cool gym- semi-outdoor (tarp windows open when warm enough) where you can watch the sunrise over the city-scape while running on the treadmill.
  19 Feb,2018
Map

Recently booked 5 stars hotels in San Francisco

Hyatt Regency San Francisco
4.5 out of 5.0
Last booking: 2 minutes ago
The Marina Inn on San Francisco Bay
3.0 out of 5.0
Last booking: 10 minutes ago
Axiom Hotel San Francisco
4.5 out of 5.0
Last booking: 10 minutes ago

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. After all, this is one of the Top 100 locations in Expedia's portfolio! You'll join the multitudes of holidaymakers who have made San Francisco so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in San Francisco and indulge in the finer things in life for a while.

5-Star Hotels in San Francisco

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in San Francisco are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and San Francisco 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in San Francisco! Choose one of our San Francisco 5-star hotels today and soothe yourself in luxe surroundings at your convenience.