Walk with your tour guide in small group around the most important places of the city from the Esplanada square till the view for Mouragia. Walk around the first place of Opera in Modern Greece- now the Town hall, around the copy of famous Rue de Rivoli in Paris - Liston and church of Saint Spiridon, the patron protector of the island, walk through Campielo with view of Mouragia and the palace of Saint George and Michel, where is now the Museum of Asian art and you will get the answer, what the museum is there :)