A large suspension bridge, industrial cranes, and a calm river.

Five Star Hotels in Panama Canal Zone

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Check availability on Panama Canal Zone 5 Star Hotels

This weekend
10 Jul - 12 Jul
Next weekend
17 Jul - 19 Jul

Our top choices for Panama Canal Zone 5-star hotels

Outdoor pool, pool loungers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (5,699 reviews)
"Great Location, good food."
United States
Yohan
The price is S$187
includes taxes & fees
26 Jul - 27 Jul
Hotel Riu Plaza Panama
2 bars/lounges, poolside bar

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
"yes, nice breakfast"
United States
Fernando
The price is S$391
includes taxes & fees
1 Aug - 2 Aug
Waldorf Astoria Panama
Restaurant

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,005 reviews)
"Very clean nice staff and convenient"
United States
Ruth P
The price is S$397
includes taxes & fees
17 Jul - 18 Jul
W Panama
4 outdoor pools, free pool cabanas, pool umbrellas

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff were really nice"
United States
MaryJane
The price is S$408
includes taxes & fees
7 Aug - 8 Aug
JW Marriott Panama
Premium bedding, down duvets, pillow-top beds, minibar

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (682 reviews)
"Wonderful stay!!"
United States
Vesna
The price is S$582
includes taxes & fees
16 Jul - 17 Jul
Sofitel Legend Casco Viejo, Panama City
Outdoor pool, pool umbrellas

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (363 reviews)
"Great stay! We enjoyed the hospitality!"
United States
Craig
Hyatt Regency Panama City
40-inch Smart TV with cable channels, TV

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (243 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is S$181
includes taxes & fees
24 Jul - 25 Jul
Renaissance Panama City Hotel
View from property

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (708 reviews)
"Stunning ! Beautiful Hotel ! Excelent Service Delicious Food Luxury modern room Can’t wait to go back ! Love it so much !"
United States
Marina
The price is S$383
includes taxes & fees
17 Jul - 18 Jul
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
3 outdoor pools, pool umbrellas, pool loungers

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1,003 reviews)
"This is an excellent hotel and would highly recommend."
United States
Shernon
The price is S$293
includes taxes & fees
26 Jul - 27 Jul
The Westin Playa Bonita Panama
Outdoor pool

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,007 reviews)
"Very nice hotel in the heart of the city. Friendly staff and very nice rooms."
United States
Ashley
The price is S$319
includes taxes & fees
8 Aug - 9 Aug
Hilton Panama
Couples treatment room(s), sauna, steam room, body treatments

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1,003 reviews)
"Great Hotel and location, the staff was very friendly, we enjoyed our stay."
United States
Rafael
The price is S$316
includes taxes & fees
17 Jul - 18 Jul
Bristol Panama, a Registry Collection Hotel
View from property

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1,000 reviews)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Lobby

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1,000 reviews)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
The price is S$195 per night from 7 Aug to 8 Aug
S$195
7 Aug - 8 Aug
includes taxes & fees
8.6/10 Excellent! (2,617 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—rainforests, golf courses and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
A large steel bridge spanning a river with a cargo ship beneath it.

Top Panama Canal Zone Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"I enjoyed breakfast. They provided authentic Panamanian food, in addition to American breakfast."
Monica 5-night trip
Posted 11 hours ago
Hotel Riu Plaza Panama
JW Marriott Panama

JW Marriott Panama

10/10 Excellent
"Súper tranquilo y muy limpio todo y el trato de los trabajadores muy cordial"
Antonio 3-night trip
Posted 1 day ago
JW Marriott Panama

Find out more about Panama Canal Zone

Stay in Luxury: 5 Star Hotels in Panama Canal Zone

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Panama Canal Zone trip. You'll join the multitudes of holidaymakers who have made Panama Canal Zone so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Panama Canal Zone and indulge in the finer things in life for a while.

5-Star Hotels in Panama Canal Zone

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Panama Canal Zone are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Panama Canal Zone 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Panama Canal Zone! Choose one of our Panama Canal Zone 5-star hotels today and soothe yourself in luxe surroundings at your convenience.


Expedia India is rated 4 stars by Feefo based on 1038 reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on things like when you plan to go and the length of your holiday. Our insider tip for bagging an awesome deal? Use our pricing filters to compare all of the available accommodation for your selected dates.

  • Search for the lowest price per night from S$187

What makes a hotel 5 stars in Panama Canal Zone?
In Panama Canal Zone, a hotel must offer a specific number of upscale features to earn 5 stars. These may include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their exceptional standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer extra touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Expedia's filters are the quickest way to narrow down what you're looking for. Check the "All inclusive" and "5-star" boxes to see the most luxurious hotels in Panama Canal Zone where your meals, room, entertainment and activities are included in the price. At these getaways, your holiday is pure extravagance from the moment you check in.