A large suspension bridge, industrial cranes, and a calm river.

Five Star Hotels in Panama Canal Zone

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Check availability on Panama Canal Zone 5 Star Hotels

Tonight
22 Aug - 23 Aug
Tomorrow
23 Aug - 24 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sept - 6 Sept

Our top choices for Panama Canal Zone 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern hotel room with a dining area, a TV, and a city view.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Towona
S$172
includes taxes & fees
16 Sept - 17 Sept
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Michael
S$371
includes taxes & fees
30 Aug - 31 Aug
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Josh
S$478
includes taxes & fees
8 Sept - 9 Sept
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Tad Olivet Ottinger Welcome
S$177
includes taxes & fees
28 Aug - 29 Aug
Renaissance Panama City Hotel
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern interior with a central seating area, potted plants, and a staircase.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern building with a sign reading 'HYATT REGENCY.'

5. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Deanna
S$311
includes taxes & fees
15 Sept - 16 Sept
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Carlos
S$375
includes taxes & fees
7 Sept - 8 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.

7. W Panama

W Panama
Bella Vista
United States
Anna Lee
S$364
includes taxes & fees
19 Sept - 20 Sept
W Panama
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A terrace with seating and a view of the ocean.

8. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Benjamin A
S$379
includes taxes & fees
11 Sept - 12 Sept
JW Marriott Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A beachfront hotel with a large building, a beach, and a clear sky.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.

9. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Bruce
S$288
includes taxes & fees
19 Sept - 20 Sept
The Westin Playa Bonita Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern interior with a spiral staircase, a large window, and a seating area.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern bar area with seating and a view of the city.

10. Hilton Panama

Hilton Panama
Bella Vista
United States
William
S$332
includes taxes & fees
18 Sept - 19 Sept
Hilton Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A person performing a yoga pose in a living room with a large window and a sofa.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Rafael
S$314
includes taxes & fees
28 Aug - 29 Aug
Bristol Panama, a Registry Collection Hotel

12. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
S$331
includes taxes & fees
13 Sept - 14 Sept
Megapolis Hotel Panamá
A rooftop pool with lounge chairs and a city skyline in the background.

13. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
S$156
includes taxes & fees
23 Aug - 24 Aug
Waymore Hotel Spa and Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
S$184
22 Sept - 23 Sept
includes taxes & fees
8.6/10 Excellent! (2,703 reviews)
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
S$256
22 Sept - 23 Sept
includes taxes & fees
9.2/10 Wonderful! (1,013 reviews)
Central Hotel Panama Casco Viejo
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Calle Augusto Samuel Boyd y Calle Eusebi Panama City
S$216
23 Aug - 24 Aug
includes taxes & fees
Waymore Hotel Spa & Casino
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—rainforests, golf courses and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
A large steel bridge spanning a river with a cargo ship beneath it.

Top Panama Canal Zone Hotel Reviews

Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"The staff was wonderful and the amenities were a plus the house keeper that was assigned to our room 419 was very respectful and kind I would definitely recommend people to stay at this hotel looking forward to returning"
Corey 5-night trip
Posted 4 hours ago
Renaissance Panama City Hotel
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"The room was clean, the breakfast was fresh and provided a wide variety. The view from my room was amazing"
Shernelle 7-night trip
Posted 7 hours ago
Hotel Riu Plaza Panama
Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"Everything was excellent No complaints about anything"
Rufino 4-night trip
Posted 12 hours ago
Hyatt Regency Panama City

Find out more about Panama Canal Zone

Stay in Luxury: 5 Star Hotels in Panama Canal Zone

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Panama Canal Zone trip. You'll join the multitudes of holidaymakers who have made Panama Canal Zone so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Panama Canal Zone and indulge in the finer things in life for a while.

5-Star Hotels in Panama Canal Zone

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Panama Canal Zone are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Panama Canal Zone 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Panama Canal Zone! Choose one of our Panama Canal Zone 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

Expedia India is rated 4 stars by Feefo based on 1038 reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on things like when you plan to go and the length of your holiday. Our insider tip for bagging an awesome deal? Use our pricing filters to compare all of the available accommodation for your selected dates.
  • Search for the lowest price per night from S$184
What makes a hotel 5 stars in Panama Canal Zone?
In Panama Canal Zone, a hotel must offer a specific number of upscale features to earn 5 stars. These may include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their exceptional standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer extra touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Expedia's filters are the quickest way to narrow down what you're looking for. Check the "All inclusive" and "5-star" boxes to see the most luxurious hotels in Panama Canal Zone where your meals, room, entertainment and activities are included in the price. At these getaways, your holiday is pure extravagance from the moment you check in.