Avenida Central
Visit Avenida Central
Tours & day trips
See all 362 activities
Catapult Tour Panama
Private & custom tours
See all 144 activities
Jungle quad bike Waterfall and Zipline Adventure from Panama City
Cruises & boat tours
See all 44 activities
Full-Day Catamaran Sailing Caribbean Beaches with Snorkelling and Lunch
Classes & workshops
See all 11 activities
Learn about Panama cocoa and create your own chocolate bar
Air, helicopter & balloon tours
See all 6 activities
Charter Flights Panama City
Popular places to visit
Ancon Hill
Explore the great outdoors at Ancon Hill, a lovely green space in Ancon. Visit the shops and top-notch restaurants in this culturally rich area.
Metropolitan Cathedral of Panama
Learn about the local history of Panama City with a stop at Metropolitan Cathedral of Panama. Visit the shops and top-notch restaurants in this vibrant area.
Independence Square
You can learn about the history of Panama City with a trip to Independence Square. Visit the shops and top-notch restaurants in this vibrant area.
Museum of Contemporary Art Panama
You can spend time browsing the exhibits at Museum of Contemporary Art Panama in Ancon. Visit the shops and top-notch restaurants in this vibrant area.
Afro Antillean Museum
You can browse the exhibits at Afro Antillean Museum, a museum with a story of its own, during your holiday in Panama City. Stroll along the seaside or visit the shops in this culturally rich area.
Museum of Natural Science
You can browse the exhibits at Museum of Natural Science, a museum with a story of its own, during your travels to Panama City. Stroll along the seaside or visit the shops in this vibrant area.
Top Avenida Central Hotel Deals
Check availability on hotels close to Avenida Central
Explore a world of travel with Expedia
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.