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Gay friendly Hotels in Cape Girardeau
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Our top choices for Cape Girardeau LGBT-friendly hotels
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1004)
"Great place and staff, very accommodating!"
Megan
The price is S$130
includes taxes & fees
1 Jan - 2 Jan, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
Brian
The price is S$132
includes taxes & fees
4 Jan - 5 Jan, 2026
9.0 out of 10, Wonderful, (1001)
"Great stay"
Heather
The price is S$101
includes taxes & fees
1 Jan - 2 Jan, 2026
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (468)
"Very nice hotel within walking distance to many good restaurants "
Vicky
The price is S$182
includes taxes & fees
11 Jan - 12 Jan, 2026
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
Ray
The price is S$130
includes taxes & fees
1 Jan - 2 Jan, 2026
9.6 out of 10, Exceptional, (785)
"Excellent stay"
Christina
The price is S$153
includes taxes & fees
4 Jan - 5 Jan, 2026
8.2 out of 10, Very good, (886)
"Room was clean and spacious."
George
The price is S$108
includes taxes & fees
25 Jan - 26 Jan, 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical CenterCape Girardeau
9.0 out of 10, Wonderful, (1003)
"Nice place for a stay at a reasonable price."
Arthur
The price is S$101
includes taxes & fees
1 Jan - 2 Jan, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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