Defiance Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to S$134 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Defiance

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
The price is S$131 per night from 3 Feb to 4 Feb
S$131
3 Feb - 4 Feb
includes taxes & fees
7.8/10 Good! (1,091 reviews)
Great room, great people, great breakfast

Reviewed on 2 Feb, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl Wildwood MO
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (1,625 reviews)
Room was very fun layout. Grocery store and restaurants near by. Pool was very small but we didn't use the pool. Staff was great.

Reviewed on 25 Jan, 2026

Get rates
The Wildwood Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
The price is S$287 per night from 8 Feb to 9 Feb
S$287
8 Feb - 9 Feb
includes taxes & fees
8.4/10 Very Good! (1,006 reviews)
Spotless room

Reviewed on 26 Jan, 2026

Ameristar Casino Resort and Spa
See all 862 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Forest Park which includes a pond, flowers and modern architecture

Forest Park

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

Forest Park

What to do in Defiance

Adventure Valley Paintball Fun

Adventure Valley Paintball Park

S$15
per adult
Adventure Valley Paintball Park
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

S$218
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St Louis Self-Guided Driving and Walking Audio Tour

St Louis Self-Guided Driving and Walking Audio Tour

S$22
per traveller
St Louis Self-Guided Driving and Walking Audio Tour
See all activities in Defiance

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.