Cape Girardeau County Hotels: Top Hotel and Accommodation Destinations in Cape Girardeau County | Expedia

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Cape Girardeau County
Missouri
United States of America
Hotels
Expedia.com.sg

Holiday Rentals in Cape Girardeau County Cape Girardeau County Car Hire Cape Girardeau County Holidays

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Top Cities in Cape Girardeau County

A calm body of water, a sandy beach, and a forested area in the distance.

A river, a large white building, and a cityscape.

A tree with white blossoms in a grassy area surrounded by trees.

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Our top choices for Cape Girardeau County hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property

Cape Girardeau

9.6 out of 10, Exceptional, (1,008 reviews)

9.6/10

Exceptional

(1,008 reviews)

"Great stay! Hot tub was enjoyable and the staff was super friendly!"

"Great stay! Hot tub was enjoyable and the staff was super friendly!"

United States

Chris

The price is S$144

S$144

includes taxes & fees

1 Nov - 2 Nov

Drury Plaza Hotel Cape Girardeau Conference Center

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

2. The Riverview

4.0 star property

Cape Girardeau

9.4 out of 10, Exceptional, (682 reviews)

9.4/10

Exceptional

(682 reviews)

"Great property, clean well maintained. Well lit parking lots. No breakfast other than Starbux…"

"Great property, clean well maintained. Well lit parking lots. No breakfast other than Starbux…"

United States

Scotty

The price is S$147

S$147

includes taxes & fees

27 Oct - 28 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

3. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 star property

Cape Girardeau

9.2 out of 10, Wonderful, (1,006 reviews)

9.2/10

Wonderful

(1,006 reviews)

"Room was clean and staff was very friendly"

"Room was clean and staff was very friendly"

United States

Troy

The price is S$104

S$104

includes taxes & fees

1 Nov - 2 Nov

Pear Tree Inn Cape Girardeau West

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

4. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property

Cape Girardeau

9.4 out of 10, Exceptional, (1,002 reviews)

9.4/10

Exceptional

(1,002 reviews)

"The food was excellent"

"The food was excellent"

United States

DENNIS

The price is S$130

S$130

includes taxes & fees

1 Nov - 2 Nov

Drury Inn & Suites Cape Girardeau

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

5. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property

Cape Girardeau

9.4 out of 10, Exceptional, (1,001 reviews)

9.4/10

Exceptional

(1,001 reviews)

"Perfect location, beds were awesome & staff were friendly & accommodating!"

"Perfect location, beds were awesome & staff were friendly & accommodating!"

United States

Rebecca

The price is S$144

S$144

includes taxes & fees

19 Nov - 20 Nov

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property

Jackson

9.0 out of 10, Wonderful, (877 reviews)

9.0/10

Wonderful

(877 reviews)

"Clean, good location, comfortable beds"

"Clean, good location, comfortable beds"

United States

Elaine

The price is S$111

S$111

includes taxes & fees

8 Nov - 9 Nov

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A hotel room with two beds, a brick wall, and a wooden headboard.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

7. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property

Jackson

9.6 out of 10, Exceptional, (1,004 reviews)

9.6/10

Exceptional

(1,004 reviews)

"Clean room affordable and great breakfast I would definitely go back!"

"Clean room affordable and great breakfast I would definitely go back!"

United States

Lyn

The price is S$108

S$108

includes taxes & fees

1 Nov - 2 Nov

Drury Inn & Suites Jackson MO

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

8. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2.5 star property

Cape Girardeau

7.0 out of 10, Good, (809 reviews)

7.0/10

Good

(809 reviews)

"Clean rooms, nice staff"

"Clean rooms, nice staff"

United States

Dayanita

The price is S$86

S$86

includes taxes & fees

1 Nov - 2 Nov

Quality Inn Cape Girardeau North

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

A hotel room with a bed, a TV, a desk, and a chair.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

9. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property

Cape Girardeau

8.0 out of 10, Very good, (1,003 reviews)

8.0/10

Very good

(1,003 reviews)

"Very enjoyable stay, great staff."

"Very enjoyable stay, great staff."

United States

Samuel

The price is S$111

S$111

includes taxes & fees

15 Nov - 16 Nov

Candlewood Suites Cape Girardeau by IHG

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

10. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3.0 star property

Cape Girardeau

9.4 out of 10, Exceptional, (236 reviews)

9.4/10

Exceptional

(236 reviews)

"Great hotel…!!"

"Great hotel…!!"

United States

Carlos

The price is S$146

S$146

includes taxes & fees

1 Nov - 2 Nov

Fairfield Inn & Suites by Marriott Cape Girardeau

A modern retail area with a display of local items and snacks.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

11. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 star property

Cape Girardeau

9.6 out of 10, Exceptional, (195 reviews)

9.6/10

Exceptional

(195 reviews)

"Had a great stay friendly staff very clean facilities!"

"Had a great stay friendly staff very clean facilities!"

United States

Shannon

The price is S$130

S$130

includes taxes & fees

1 Nov - 2 Nov

Tru By Hilton Cape Girardeau

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A spacious living room with a sofa set, a coffee table, and a dining area.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A lobby with seating areas, a reception desk, and a bar.

12. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property

Cape Girardeau

9.6 out of 10, Exceptional, (554 reviews)

9.6/10

Exceptional

(554 reviews)

"Perfect place and location for our girls trip. The staff was excellent!"

"Perfect place and location for our girls trip. The staff was excellent!"

United States

Kristin

The price is S$181

S$181

includes taxes & fees

1 Nov - 2 Nov

Courtyard by Marriott Cape Girardeau Downtown

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A bathroom with a marble wall and a white bathtub.

13. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

2.5 star property

Cape Girardeau

6.2 out of 10, (243 reviews)

6.2/10

(243 reviews)

"Clean affordable and friendly staff"

"Clean affordable and friendly staff"

United States

Hope

The price is S$105

S$105

includes taxes & fees

25 Oct - 26 Oct

Town House Inn Cape Giradreau

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

An outdoor patio with stone walls, wicker furniture, and large windows.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

14. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

2.5 star property

Cape Girardeau

9.6 out of 10, Exceptional, (854 reviews)

9.6/10

Exceptional

(854 reviews)

"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."

"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."

United States

Brittany

The price is S$153

S$153

includes taxes & fees

1 Nov - 2 Nov

Hampton Inn Cape Girardeau I 55 East

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property

Jackson

8.0 out of 10, Very good, (784 reviews)

8.0/10

Very good

(784 reviews)

"Our room was clean and spacious. We had icy cold A/C and it was quiet there for the night!"

"Our room was clean and spacious. We had icy cold A/C and it was quiet there for the night!"

United States

VICTORIA

The price is S$105

S$105

includes taxes & fees

10 Nov - 11 Nov

Comfort Suites Jackson-Cape Girardeau

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

Exterior

16. Town House Inn

2.5 star property

Jackson

7.6 out of 10, Good, (448 reviews)

7.6/10

Good

(448 reviews)

"Great owners "

"Great owners "

United States

Jennifer

The price is S$99

S$99

includes taxes & fees

21 Oct - 22 Oct

A rustic wooden cabin with a porch, outdoor seating, and a view of a lush green landscape.

A rustic wooden interior with a dining area, large windows, and a view of the outdoors.

A rustic cabin interior with wooden beams, a green door, and a cozy seating area with patterned cushions and a round coffee table.

A log cabin room with a bed, curtains, a lamp, and a green door.

17. Private Getaway on 270 Acres w/ Lake: Swim & Canoe

Private Getaway on 270 Acres w/ Lake: Swim & Canoe

2.0 star property

Advance

Private Getaway on 270 Acres w/ Lake: Swim & Canoe

A spacious living area with a sofa, a coffee table, and a TV.

A modern kitchen with white cabinets, a central island, and a stainless steel refrigerator.

A modern kitchen with white cabinets, a central island, and a dining area with a wooden table and chairs.

A two-story house with a garage, a brick section on the side, and a clear sky.

18. Deck & Large Yard! Family Haven in Cape Girardeau

Deck & Large Yard! Family Haven in Cape Girardeau

3.0 star property

Cape Girardeau

Deck & Large Yard! Family Haven in Cape Girardeau

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Cape Girardeau County Hotel Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"The room and property was very clean! Quite area! In a safe area! Breakfast was good! Easy check in and out!"

Pamela 1-night trip

Posted 2 hours ago

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent

"Lots of parking , clean room ,beautiful atmosphere breakfast was good."

Geraldine 1-night trip

Posted 12 hours ago

Drury Inn & Suites Jackson MO

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

10/10 Excellent

"I chose this motel due to it being close to the car rental agency I used and the bus stop for Greyhound. Sidewalks on Kingshighway would have helped but that is on the city of Cape Girardeau! :-}"

Sam 1-night trip

Posted 17 hours ago

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Stayed here for a long weekend motorcycle trip. The hotel is conveniently located near many shopping and dining choices. The room was basic but clean and quiet, and lots of channels on the tv! Staff were super friendly and helpful. I will definitely stay here again the next time I am in Cape Girardeau."

Robert 3-night trip

Posted 20 hours ago

Pear Tree Inn Cape Girardeau West

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

10/10 Excellent

"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."

Brittany 1-night trip

Posted 21 hours ago

Hampton Inn Cape Girardeau I 55 East

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

8/10 Good

"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."

Jaime 1-night trip

Posted 2 days ago

Town House Inn Cape Giradreau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

10/10 Excellent

"A new property that is very clean and well trained staff"

sterling 1-night trip

Posted 2 days ago

Tru By Hilton Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"I was surprised how reasonable the cost was considering how clean & nice all of the finishers were."

John 1-night trip

Posted 4 days ago

Courtyard by Marriott Cape Girardeau Downtown

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"Very nice facility, great staff, overall wonderful experience"

Perry 1-night trip

Posted 6 days ago

Holiday Inn Express & Suites Perryville by IHG

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