Top 10 Downtown Hotels of 2026

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Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

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Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit South Beach and Lake Keowee.

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Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Oconee Community Theatre.

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Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Oconee Community Theatre are some notable places to visit nearby.

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Top Downtown Hotel Reviews

Holiday Inn Anderson by IHG

10/10 Excellent

"Location in Anderson is very convenient. Staff was very cordial and friendly. The property is updated, clean, and comfortable. The bar and restaurant on-site is a plus."

Woodspring Suites Anderson North I-85

6/10 Okay

"Booked this property due to the ‘newness’ (2025) and it wasn’t horrible but the AC was sporadic all night. Bed wasn’t the most comfortable and I mistakenly assumed that the fridge would keep my leftover food cold without me having to change the settings (I was wrong)"

Comfort Inn & Suites Clemson - University Area

6/10 Okay

"The property was clean and the room was just like the pictures and clean, but we did have issues with the card that opens the doors on the property including the room we had to go twice to get the cards programed or scanned in order for them to work and one of them never worked so only one was working. The front office staff could be nicer the two employees that I spoke with didn't even look at me once while I was checking in or out, they were looking down or in a different direction which I thought it was rude. I also find it odd that I didn't get a receipt when checking out. The lady at the front desk said it would be emailed thru the third-party company that I made the reservation with I've never had that happened before, so I thought it was odd. But other than that, it was ok the cleaning staff was really nice. Would I stay there again probably not, would I recommend it maybe if you're in a budget, for the money I paid it was good. The breakfast was ok could use a little more variety it was the same thing every day."

Lakeside Lodge Clemson

10/10 Excellent

"We have stayed here several times in different rooms. From regular rooms up to suites. This is awesome place to stay. Always well kept, clean rooms and there is plenty of room inside and out. Whether you are in town for an archery shoot or games or just a nice weekend away. You are close to just about everything you need. Nothing shady about the area, well lit and plenty of parking. You are near the railroad tracks, but it’s no louder than the ice maker in the fridge. The brunch is great, and I am willing to guess dinner too, the restaurant is always full. The staff are great and there is on premise security."

Frequently asked questions

What is Downtown like?

Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.

Where is the best place to stay in Downtown?

Based on our traveller data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.

How many hotels will I be able to find in Downtown?

If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodation options in Downtown.

If I need to cancel my hotel reservation in Downtown, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.

What can I see and do in this Seneca neighbourhood?

Oconee County Library Seneca Branch, Blue Ridge Arts Center and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Applewood Shopping Center or Wyndham Plaza.

Hotels in Downtown

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Our top choices for Downtown hotels

Quality Inn Seneca Clemson Area US-123

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Inn @ Clemson

Liberty Hall Bed and Breakfast

Econo Lodge Lavonia I-85

Lakeside Lodge Clemson

Best Western Plus Clemson Hotel & Conference Center

Fairfield Inn & Suites Seneca Clemson Univ Area

Rodeway Inn & Suites Walhalla

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Super 8 by Wyndham Lavonia

Clemson Memorabilia House

Microtel Inn & Suites by Wyndham Anderson/Clemson

Econo Lodge Clemson - University Area

Days Inn by Wyndham Clemson

Hampton Inn & Suites Lavonia

Days Inn by Wyndham Seneca / Clemson Area

Quality Inn Clemson near University

Hilton Garden Inn Anderson

The Inn at Patrick Square

Where to stay in Downtown

Serenity Bay

Pine Ridge Point

Indian Oaks

Keowee Plantation

Top Downtown Hotel Reviews

Holiday Inn Anderson by IHG

Frequently asked questions