Downtown South San Francisco Holidays

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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown South San Francisco
A marina with various boats docked, including a yellow and white boat named 'Golden Gate'.

Fisherman's Wharf

1 out of top 10 points of interest in this area

Dating back to the middle of the 19th Century, this historic wharf has been through many incarnations. Today it’s bursting with fun, sea lions and restaurants.

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A cityscape with tall buildings, palm trees, and red double-decker buses.

Union Square

Fashion puts its best foot forward in this vast shopping plaza.

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A trolley on a street with buildings and a clock tower.

Downtown San Francisco

3 out of top 10 points of interest in this area

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and San Francisco Bay are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

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A cityscape with modern skyscrapers, a central park with pathways, and a few people walking.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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A cityscape with a prominent skyscraper, a bridge, and a mix of modern and historic buildings.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

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Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

20 Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
S$190
16 Oct - 17 Oct
includes taxes & fees
8.2/10 Very good! (2,132 reviews)
"The front staff Chris and others are the star of your hotel. There professionalism and excellent quality support and service was above standards. The two young ladies who assisted my checkin on Saturday morning September 19th were by far excellent personnel whom treated their guest with courtesy, ..."

Reviewed on 20 Sept, 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
S$280
18 Oct - 19 Oct
includes taxes & fees
9/10 Wonderful! (6,330 reviews)
"Good service"

Reviewed on 21 Sept, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
S$265
18 Oct - 19 Oct
includes taxes & fees
9/10 Wonderful! (7,680 reviews)
"Very busy. There is a line for everything. Our room had mold around the tub."

Reviewed on 21 Sept, 2026

Hotel Riu Plaza Fisherman's Wharf
See all 4,261 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown South San Francisco holiday package cost?
From just . Yes, you read that right. Our Downtown South San Francisco holiday packages are a simple way to make your dollar go further. Combine your favourite hotels, flights and car rentals and get to know this popular destination.
How do I get a cheap travel package to Downtown South San Francisco?
Bundle your bookings with Expedia to save on your next big adventure. With more than 550 airlines and 1,000,000 properties globally, your Downtown South San Francisco holiday package can be tailored exactly to suit your travel style. With all those extra dollars, why not add one or two interesting tours and activities? It's an easy way to unlock even more bargains. That dream holiday to Downtown South San Francisco is much closer than you thought!
Where should I stay in Downtown South San Francisco?
A trip to Downtown South San Francisco wouldn't be complete without seeing South San Francisco Convention Centre, Sees Candies and K1 Speed San Francisco. Spend your nights close to these top attractions and make sightseeing easy.
What are the top hotels in Downtown South San Francisco?
Book a stay at Airport Inn. It's one of this area's most sought-after hotels. Another well-known option in Downtown South San Francisco is Rustic/modern Design, Oasis City Getaway.
How far in advance should I book my Downtown South San Francisco holiday?
Travellers are generally able to look up international airfares on Expedia up to a year in advance of departure. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your journey.
What does an Expedia Downtown South San Francisco travel package include?
With Expedia, you can choose a combination of hotels, flights and car rentals to build your perfect Downtown South San Francisco travel package. Once you've made your booking, you can add on all the fun stuff like activities and tours. Don't forget, the more you bundle, the more cash you'll save!
What should I know before booking a Downtown South San Francisco travel package?
When you book your hotels, flights and car rentals together, you'll land great discounts. Whether you're organising an outdoor getaway in a chalet or prefer to stay in a ritzy city hotel, Expedia can help make it happen.
Can I choose my airline with a Downtown South San Francisco Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to select from all over the world. With all that choice, finding the ideal carrier to whisk you away to Downtown South San Francisco will be a cinch.
If I'm not able to travel, can I cancel my Downtown South San Francisco holiday package?
It's impossible to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Downtown South San Francisco holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Things to do

Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

S$125
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

S$62
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco: One day Yosemite and Giant Sequoia Tour

San Francisco: One day Yosemite and Giant Sequoias Tour

S$262
per adult
90% of travellers recommend
San Francisco: One day Yosemite and Giant Sequoias Tour
See all activities in San Francisco

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.