Photo by Caroline Nunez

Hartsville Hotels from S$81

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Hartsville hotels

The Mantissa Hotel

The Mantissa Hotel
3.0 star property
Hartsville
9.2 out of 10, Wonderful, (271)
"Very nice spacious rooms friendly staff"
United States
Duane
The price is S$214
includes taxes & fees
4 Jan - 5 Jan, 2026
The Mantissa Hotel

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
Hartsville
9.2 out of 10, Wonderful, (479)
"Staff was very friendly and accommodating!! Rooms were very clean! "
United States
Julia
The price is S$176
includes taxes & fees
9 Jan - 10 Jan, 2026
Hampton Inn & Suites Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
Hartsville
8.6 out of 10, Excellent, (681)
"very friendly older property but clean"
United States
Tamiko
The price is S$121
includes taxes & fees
17 Jan - 18 Jan, 2026
Fairfield Inn by Marriott Hartsville

The Landmark Inn

The Landmark Inn
2.5 star property
Hartsville
7.0 out of 10, Good, (315)
"Great staff"
United States
Thomas
The price is S$108
includes taxes & fees
29 Dec - 30 Dec
The Landmark Inn

Quality Inn Hartsville

Quality Inn Hartsville
2.5 star property
Hartsville
6.0 out of 10, (331)
"Lady at desk was plesant and helpful. Sstart3ed to ask for our money back"
United States
Cynthia
The price is S$90
includes taxes & fees
13 Jan - 14 Jan, 2026
Quality Inn Hartsville

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1005)
"Very good breakfast & convenient location"
United States
Diedre
The price is S$158
includes taxes & fees
4 Jan - 5 Jan, 2026
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1002)
"We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. "
United States
Marita
The price is S$139
includes taxes & fees
5 Jan - 6 Jan, 2026
Tru by Hilton Florence I-95

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1004)
"Great experience in a nice hotel in downtown."
United States
HATIM
The price is S$144
includes taxes & fees
5 Jan - 6 Jan, 2026
Hyatt Place Florence Downtown

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (559)
"Clean room, professional and courteous staff. "
United States
Felicia
The price is S$158
includes taxes & fees
7 Jan - 8 Jan, 2026
Fairfield Inn & Suites by Marriott Florence I-20

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (826)
"We had our dog and the room was good and dog amenities helpful."
United States
Cynthia
The price is S$165
includes taxes & fees
7 Jan - 8 Jan, 2026
Hampton Inn & Suites Florence-North-I-95

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
3.0 star property
Florence
8.2 out of 10, Very good, (1004)
"Clean room, good location, quick checkin"
United States
Brian
The price is S$152
includes taxes & fees
11 Jan - 12 Jan, 2026
Home2 Suites by Hilton Florence, SC

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1178)
"Great location, friendly staff. "
United States
Defelicio
The price is S$142
includes taxes & fees
18 Jan - 19 Jan, 2026
Comfort Inn & Suites Florence Center Area

Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (606)
"Special place. Great staff with an outstanding restaurant "
United States
John D
The price is S$188
includes taxes & fees
4 Jan - 5 Jan, 2026
Hotel Florence, Tapestry Collection by Hilton

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2212)
"The room was spotless and the staff was extremely courteous. "
United States
Earl
The price is S$122
includes taxes & fees
11 Jan - 12 Jan, 2026
Park Inn by Radisson Florence, SC

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very good, (31)
"Friendly staff and clean environment "
United States
john
The price is S$144
includes taxes & fees
8 Jan - 9 Jan, 2026
Spark by Hilton Florence North I-95, SC

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1005)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is S$164
includes taxes & fees
4 Jan - 5 Jan, 2026
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
3.0 star property
Florence
8.4 out of 10, Very good, (660)
"The staff was amazing and the hotel is pretty fresh in terms of amenities "
United States
Shahid
The price is S$145
includes taxes & fees
11 Jan - 12 Jan, 2026
Homewood Suites by Hilton Florence

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (933)
"Great front desk Room was spotless "
United States
Lawrence
The price is S$194
includes taxes & fees
25 Jan - 26 Jan, 2026
Staybridge Suites Florence - Civic Center by IHG

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1002)
"Pool was clean good breakfast "
United States
Ann
The price is S$153
includes taxes & fees
11 Jan - 12 Jan, 2026
Comfort Suites Florence I-95

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (489)
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
United States
Marialinda
The price is S$143
includes taxes & fees
4 Jan - 5 Jan, 2026
Residence Inn Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Hartsville attractions

Learn more about Hartsville

Stroll along the scenic Black Creek, where kayakers glide past historic buildings and lush parks. Sonoco Park's trails and Kalmia Gardens' blooms offer peaceful retreats, while Coker University's campus adds a vibrant collegiate atmosphere to this charming Southern town.

The Midnight Rooster is my go to spot in my hometown of Hartsville, SC. Great brunch and coffee! Love the courtyard!
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Hartsville Hotel Reviews

More cheap stays in Hartsville

Frequently asked questions

What's the best place to stay in Hartsville?
The Mantissa Hotel is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Hampton Inn & Suites Hartsville and Fairfield Inn by Marriott Hartsville as top options for your trip. See all available top hotels, or vacation rentals in Hartsville.
If I need to cancel my hotel reservation in Hartsville, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Hartsville.
What's the best LGBTQ-friendly place to stay in Hartsville?
Fairfield Inn by Marriott Hartsville is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Hampton Inn & Suites Hartsville is another good option for your trip. See all available hotels listed as LGBTQ-friendly in Hartsville.
What's the best dog-friendly accommodation option in Hartsville?
Quality Inn Hartsville is a top hotel for people travelling with their pets, and offers a water park and free WiFi for its human guests. Two other good options for you and your pet include The Landmark Inn and Hampton Inn & Suites Hartsville. See more pet-friendly hotel accommodations in Hartsville.
What are some accommodation options with pools in Hartsville?
Hampton Inn & Suites Hartsville is a top hotel with a pool, free buffet breakfast and free WiFi. View all hotels with pools in Hartsville.
What's the top hotel in Hartsville with an on-site water park or a water park nearby?
Quality Inn Hartsville is a popular hotel, featuring water park access, a seasonal outdoor pool and free parking. You'll find Neptune Island Waterpark within 5 minutes by car. Take a look at all hotels with or near waterparks in Hartsville.
How is it staying in Hartsville?
Visitors to Hartsville will definitely enjoy the restaurants. Tourists can also enjoy the city's university setting and shopping. In Hartsville, there are 19 hotels and other accommodation options to choose from. Find out more about Hartsville.
What is there to see in Hartsville?
Cultural venues include Hartsville Museum and Center Theatre. Landmarks like Kalmia Gardens and East Home Avenue Historic District might be worth a visit. The picturesque setting of Byerly Park and Segars-McKinnon Heritage Preserve exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Hartsville guide.
What's the seasonal weather like in Hartsville?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Hartsville is 1317 mm.

Explore a world of travel with Expedia