Top 10 Innovation District Hotels of 2026

An aerial view of a historic town with red-roofed buildings, a large stadium, and surrounding greenery.

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Our top choices for Innovation District hotels

A modern interior with a staircase, a seating area, and a colorful abstract wall design.

1. Hyatt Place Gainesville Downtown

Downtown Gainesville, 1.1 km from Innovation District

maria

includes taxes & fees

29 Sept - 30 Sept

A hotel lobby with a seating area, a sofa, a table, and a lamp.

2. Hampton Inn & Suites Gainesville-Downtown

Downtown Gainesville, 1.1 km from Innovation District

Graziella

includes taxes & fees

13 Sept - 14 Sept

A modern living room with a fireplace, comfortable seating, a flat-screen TV, and a large window.

3. Comfort Suites Gainesville near University

2.3 km from Innovation District

Gladys

includes taxes & fees

4 Oct - 5 Oct

A spacious living area with a curved ceiling, a large flat-screen TV, and a modern sofa.

4. Holiday Inn Gainesville - University Center by IHG

University Heights, 0.6 km from Innovation District

anna

includes taxes & fees

20 Sept - 21 Sept

An outdoor kitchen with a grill, a table, and chairs.

5. Home2 Suites by Hilton Gainesville Medical Center

1.9 km from Innovation District

Dylan

includes taxes & fees

4 Oct - 5 Oct

A modern building with a curved facade, a landscaped pathway, and a body of water in the foreground.

6. Hotel Eleo at the University of Florida

1.4 km from Innovation District

Luis Eduardo

includes taxes & fees

27 Sept - 28 Sept

A modern outdoor lounge area with a fire feature, seating, and a view of a pool.

7. AC Hotel by Marriott Gainesville Downtown

College Park, 0.7 km from Innovation District

SORAIDA

includes taxes & fees

7 Sept - 8 Sept

A large, two-story house with a porch, multiple windows, and a chimney.

8. Sweetwater Branch Inn

1.6 km from Innovation District

Jose

includes taxes & fees

13 Sept - 14 Sept

A modern kitchen with dark cabinets, stainless steel appliances, and a wooden ceiling.

9. Depot Village

1.1 km from Innovation District

Trisha

includes taxes & fees

7 Sept - 8 Sept

An outdoor patio area with string lights, potted plants, and outdoor furniture.

10. Gainesville Lodge

0.7 km from Innovation District

Justin

includes taxes & fees

7 Oct - 8 Oct

A hotel room with a large bed, a nightstand, a chair, a window with a view of greenery, and a beach-themed wall mural.

11. Days Inn by Wyndham Gainesville Hospital/University Area

2.4 km from Innovation District

Christy

includes taxes & fees

7 Sept - 8 Sept

A spacious hotel lobby with a curved sofa, a patterned carpet, and a large window with sheer curtains.

12. Hilton University of Florida Conference Center Gainesville

3.9 km from Innovation District

Nandini

includes taxes & fees

10 Sept - 11 Sept

A two-story motel with a sign indicating it is a Quality Inn by Choice Hotels.

13. Quality Inn Gainesville near University

2.1 km from Innovation District

"Great clean place close to VA hospital where my husband was having surgery. Staff was super friendly and very helpful when we needed to extend or stay because my husband needed to stay the night in the hospital. However, I do have to mention that I believe one of the staff was using the designated handicapped parking spot with no ads signage. I understand the parking lot was mostly empty but those spots should only be taken by disabled people."

Lisa

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.

14. Drury Inn & Suites Gainesville

5.9 km from Innovation District

James

includes taxes & fees

10 Sept - 11 Sept

A multi-story hotel with a central entrance, palm trees, and a clear sky.

15. Country Inn & Suites by Radisson, Gainesville, FL

6.2 km from Innovation District

Henry

includes taxes & fees

13 Sept - 14 Sept

A dining area with a round table, chairs, a chandelier, and a spiral staircase with a view to the outside.

16. University Inn Gainesville

1.6 km from Innovation District

Jhonny

includes taxes & fees

7 Sept - 8 Sept

A modern bar area with a long counter, green bar stools, and a television displaying a golf game.

17. Fairfield Inn & Suites by Marriott Gainesville I-75

5.4 km from Innovation District

Jesse

includes taxes & fees

7 Sept - 8 Sept

A modern hotel with a flat roof, multiple floors, and a prominent 'aloft' sign.

18. Aloft by Marriott Gainesville University Area

4.4 km from Innovation District

Elizabeth H

includes taxes & fees

20 Sept - 21 Sept

A hotel room with a bed, two bedside tables with lamps, a large bathtub, and green walls.

19. Sleep Inn & Suites University/Shands

5.8 km from Innovation District

prakasa Babu

includes taxes & fees

1 Oct - 2 Oct

A swimming pool with lounge chairs and a gazebo, surrounded by palm trees and a building with a stone facade.

20. Holiday Inn Express & Suites Gainesville I-75 by IHG

5.8 km from Innovation District

Alex

includes taxes & fees

7 Oct - 8 Oct

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Where to stay in Innovation District

Find the best Innovation District areas for the activities you enjoy most.

University Heights

University Heights might not have many top sights, but Ben Hill Griffin Stadium and Hippodrome State Theatre are two attractions nearby that you can check out.

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A cityscape at sunset with buildings, a street, and a palm tree.

Downtown Gainesville

If you're looking for some top things to see and do in Downtown Gainesville and surrounding area, you can visit Hippodrome State Theatre and Thomas Center.

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A tall brick tower with a clock, surrounded by palm trees and a building with a flat roof.

College Park

If you're looking for some top things to see and do in College Park and surrounding area, you can visit Ben Hill Griffin Stadium and Stephen C. O'Connell Center.

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A lakeside building surrounded by trees and a calm body of water.

Duckpond

If you're looking for some top things to see and do in Duckpond and surrounding area, you can visit Thomas Center and Hippodrome State Theatre.

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A dense forest with sunlight filtering through the trees.

Haile Plantation

If you're spending some time in Haile Plantation, Haile Village Center and Haile Plantation Golf and Country Club are top sights worth seeing.

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Top Innovation District Hotel Reviews

Country Inn & Suites by Radisson, Gainesville, FL

10/10 Excellent

"I would highly recommend this hotel. It is conveniently located right off the freeway, with plenty of parking. The staff is friendly and accommodating. The room was large, the beds were comfortable, and there is a fantastic free continental breakfast. There is a pool, gym and laundry facilities. And the price is very reasonable."

Sleep Inn & Suites University/Shands

10/10 Excellent

"Very accommodating staff. We got there before check in and they gave us a different room without question. They had popcorn and cookies available for free too which was great! The breakfast was alright. Small selection but didnt expect much given the small scale of the hotel. The shower had some hair in it that wasnt ours... but overall a decent stay"

Frequently asked questions

What's it like in Innovation District?

Travellers to the Innovation District neighbourhood in Gainesville will be sure to enjoy their stay.

How many hotels can I expect to find in Innovation District?

When you want to put your feet up after a day of exploring the sights in Gainesville, you can choose from 19 Expedia hotels and other accommodation options in Innovation District.

If I need to cancel my hotel reservation in Innovation District, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Innovation District.

What are the top things to see and do in Innovation District?

Hippodrome State Theatre, Cade Museum for Creativity and Invention and Ben Hill Griffin Stadium are just a few of the places to visit in and around Innovation District. Depot Park and Matheson History Museum are also worth a visit when you're out sightseeing in Gainesville.

Hotels in Innovation District

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Our top choices for Innovation District hotels

1. Hyatt Place Gainesville Downtown

2. Hampton Inn & Suites Gainesville-Downtown

3. Comfort Suites Gainesville near University

4. Holiday Inn Gainesville - University Center by IHG

5. Home2 Suites by Hilton Gainesville Medical Center

6. Hotel Eleo at the University of Florida

7. AC Hotel by Marriott Gainesville Downtown

8. Sweetwater Branch Inn

9. Depot Village

10. Gainesville Lodge

11. Days Inn by Wyndham Gainesville Hospital/University Area

12. Hilton University of Florida Conference Center Gainesville

13. Quality Inn Gainesville near University

14. Drury Inn & Suites Gainesville

15. Country Inn & Suites by Radisson, Gainesville, FL

16. University Inn Gainesville

17. Fairfield Inn & Suites by Marriott Gainesville I-75

18. Aloft by Marriott Gainesville University Area

19. Sleep Inn & Suites University/Shands

20. Holiday Inn Express & Suites Gainesville I-75 by IHG

Where to stay in Innovation District

University Heights

Downtown Gainesville

College Park

Duckpond

Haile Plantation

Top Innovation District Hotel Reviews

Country Inn & Suites by Radisson, Gainesville, FL

Frequently asked questions

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