Default HTG hotel image

La Mesa Holiday Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
23 Oct - 25 Oct
In two months
4 Dec - 6 Dec
In three months
1 Jan - 3 Jan
In four months
29 Jan - 31 Jan

Our top choices for La Mesa holiday rentals

A modern cabin with a sloped roof, surrounded by trees, and a gravel path leading to the entrance.

1. Tiny Cabin

Tiny Cabin
3.0 star property
Panamá
10.0 out of 10, Exceptional, (1 review)
The price is S$188
includes taxes & fees
12 Oct - 13 Oct
Tiny Cabin
A building with a sign reading 'Lilia House' and a decorative wall with a sign stating 'Cada Familia tiene una.'

2. Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is S$93
includes taxes & fees
11 Oct - 12 Oct
Swette Love 10 Minutes From the Airport Tocumen
A rooftop pool with a city view, lounge chairs, and a clear sky.

3. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (390 reviews)
"Nice place good location"
United States
Rame
The price is S$143
includes taxes & fees
29 Oct - 30 Oct
Corporate Stays Arcadia | Executive Furnished Apartments
A swimming pool with lounge chairs, surrounded by greenery and tall buildings in the background.

4. Apex Executive Apartments - Dovle

Apex Executive Apartments - Dovle
2.0 star property
Parque Lefevre
The price is S$253
includes taxes & fees
11 Oct - 12 Oct
Apex Executive Apartments - Dovle
A modern outdoor swimming pool with a clear view of a tall building in the background.

5. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (38 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is S$196
includes taxes & fees
17 Oct - 18 Oct
Dovle Residences by HMS-Preferred Member
A modern living room with a sofa, coffee table, and a staircase leading to an upper floor.

6. Stylish Apartment With Pool Gym in Panama

Stylish Apartment With Pool Gym in Panama
2.0 star property
San Francisco
8.0 out of 10, Very good, (1 review)
"Would stay here again"
United States
Stepp
The price is S$226
includes taxes & fees
16 Oct - 17 Oct
Stylish Apartment With Pool Gym in Panama
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

7. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (234 reviews)
"very nice place to stay"
United States
purabi
The price is S$252
includes taxes & fees
11 Oct - 12 Oct
Boutique Apartments Panamá Coco del Mar
A rooftop pool with lounge chairs, offering a city view.

8. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (49 reviews)
"Staff was great. Room has spectacular views. Air conditioning was great, super quiet in the bedroom. Rooftop pool and patio was delightful. Loved our stay!"
Canada
Gary
The price is S$194
includes taxes & fees
11 Oct - 12 Oct
Boutique Apartments Atlapa
A playground with slides and climbing structures, surrounded by a fenced area with a view of tall buildings.

9. The Hub by Boutique Apartments

The Hub by Boutique Apartments
3.0 star property
San Francisco
The price is S$232
includes taxes & fees
20 Oct - 21 Oct
The Hub by Boutique Apartments
A spa area with two hot tubs and lounge chairs.

10. 2BR at First del Sol Modern & Stylish

2BR at First del Sol Modern & Stylish
2.0 star property
San Francisco
The price is S$309
includes taxes & fees
8 Oct - 9 Oct
2BR at First del Sol Modern & Stylish
A high-rise hotel with a modern design, featuring a prominent entrance and multiple balconies.

11. Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is S$166
includes taxes & fees
26 Oct - 27 Oct
Modern Apartments at the Hub City views
An elevator with a digital display showing the number 3, a sign above it reading 'PISO-3', and two safety signs on the wall.

12. Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
2.0 out of 10, (1 review)
"La habitacion terrible, edificio sucio ubicacion pesima "
Mexico
caleb
The price is S$125
includes taxes & fees
9 Oct - 10 Oct
Charming 3 Bedroom Apartment in San Miguelito, Panama City
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

13. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is S$259
includes taxes & fees
1 Nov - 2 Nov
Living 73 Panamá by Boutique Apartments
Balcony

14. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (65 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is S$191
includes taxes & fees
18 Oct - 19 Oct
San Francisco by Wynwood House
A restaurant with a modern glass facade, wooden seating, and a sign indicating valet parking.

15. Modern Apartments PH Living 73 SF

Modern Apartments PH Living 73 SF
3.5 star property
San Francisco
8.0 out of 10, Very good, (4 reviews)
"To the owner, it would help if the top sheet is larger than the bed, difficult for two people to cover themselves"
United States
Dawid
The price is S$108
includes taxes & fees
8 Oct - 9 Oct
Modern Apartments PH Living 73 SF
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

16. Brighthaven 1br at Panama old Town

Brighthaven 1br at Panama old Town
2.0 star property
San Francisco
The price is S$190
includes taxes & fees
10 Oct - 11 Oct
Brighthaven 1br at Panama old Town
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

17. Cozy Urban Loft 1br Near Coast

Cozy Urban Loft 1br Near Coast
2.0 star property
San Francisco
The price is S$190
includes taxes & fees
11 Oct - 12 Oct
Cozy Urban Loft 1br Near Coast
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

18. Where Comfort Meets Location 1BR

Where Comfort Meets Location 1BR
2.0 star property
San Francisco
The price is S$190
includes taxes & fees
14 Oct - 15 Oct
Where Comfort Meets Location 1BR
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

19. Modern Loft-style 1br Apt at Coco del Mar

Modern Loft-style 1br Apt at Coco del Mar
2.0 star property
San Francisco
The price is S$173
includes taxes & fees
12 Oct - 13 Oct
Modern Loft-style 1br Apt at Coco del Mar
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

20. Relaxing 2br Apt at Coco del mar

Relaxing 2br Apt at Coco del mar
2.0 star property
San Francisco
The price is S$226
includes taxes & fees
10 Oct - 11 Oct
Relaxing 2br Apt at Coco del mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top La Mesa Hotel Reviews

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport

10/10 Excellent
"Loved this unique hotel..everything from the ambience to the staff, would recommend this quaint hotel to everyone!"
Teri 1-night trip
Posted 18 hours ago
ORHO Hotel Boutique 15 Minutes from PTY Airport

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals close to the most popular sights in La Mesa, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in La Mesa?

While exploring the area, visit family-friendly sights like Chepo Youth Recreation Center, or get outside and enjoy nature at Chagres National Park. In the wider area, you’ll find Metromall Panama and Los Pueblos Commercial Center.

What’s a holiday rental in La Mesa like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in La Mesa. Holiday rentals provide amenities like laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you to travel. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a great option for families.