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Hotels in Cherokee Seneca

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Check prices for these dates

Tonight
23 Dec - 24 Dec
Tomorrow
24 Dec - 25 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Cherokee Seneca hotels

Lobby
Drury Inn & Suites Louisville East

Drury Inn & Suites Louisville East

Drury Inn & Suites Louisville East
3.0 star property
9.3 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1005)
"Room was great,staff was awsome,food delicious. "
United States
Daniel
The price is S$136
includes taxes & fees
28 Dec - 29 Dec
Drury Inn & Suites Louisville East
Exterior
Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville
2.5 star property
19.2 km from Cherokee Seneca
9.4 out of 10, Exceptional, (409)
"Breakfast was good"
United States
Chantal
The price is S$133
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Louisville Shepherdsville
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 6.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (3880)
"Great place to stay! "
United States
Rochelle
The price is S$202
includes taxes & fees
29 Dec - 30 Dec
Galt House Hotel Trademark Collection by Wyndham
Free daily on-the-go breakfast
Hampton Inn Simpsonville

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
29.6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (904)
"Would stay again"
United States
Chris
The price is S$128
includes taxes & fees
29 Dec - 30 Dec
Hampton Inn Simpsonville
Exterior
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd
3.0 star property
17.2 km from Cherokee Seneca
8.4 out of 10, Very good, (926)
"Good cleanliness and helpful staff,good bed and amenities."
United States
Edward
The price is S$113
includes taxes & fees
3 Jan - 4 Jan, 2026
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1662)
"very clean throughout, helpful staff,very nice breakfast"
United States
Wayne
The price is S$124
includes taxes & fees
11 Jan - 12 Jan, 2026
Holiday Inn Express & Suites Louisville Downtown by IHG
Lobby
Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
8.8 out of 10, Excellent, (1041)
"Big nice room, friendly staff "
United States
Kim
The price is S$152
includes taxes & fees
25 Dec - 26 Dec
Hawthorn Suites by Wyndham Louisville East
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1713)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property
Interior entrance
Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo
2.5 star property
3.7 km from Cherokee Seneca
8.4 out of 10, Very good, (1196)
"Place was nice and staff very friendly"
United States
Thelma
The price is S$98
includes taxes & fees
12 Jan - 13 Jan, 2026
Wingate by Wyndham Louisville Fair and Expo
Terrace/patio
Hampton Inn Louisville - Northeast

Hampton Inn Louisville - Northeast

Hampton Inn Louisville - Northeast
2.5 star property
13.8 km from Cherokee Seneca
9.0 out of 10, Wonderful, (687)
"Good hotel"
United States
Sotirios
The price is S$117
includes taxes & fees
1 Jan - 2 Jan, 2026
Hampton Inn Louisville - Northeast
Snack bar
Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South
2.5 star property
19.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (840)
"Excellent service from check in to check out highly recommend very clean "
United States
Rebecca
The price is S$116
includes taxes & fees
11 Jan - 12 Jan, 2026
Tru by Hilton Shepherdsville Louisville South
Beach
Hilton Garden Inn Louisville/Northeast

Hilton Garden Inn Louisville/Northeast

Hilton Garden Inn Louisville/Northeast
3.0 star property
12.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (238)
"staff friendly and very helpful; room needs updating; parking was restricted because of nearby construction"
United States
Janice
The price is S$131
includes taxes & fees
26 Dec - 27 Dec
Hilton Garden Inn Louisville/Northeast
Exterior
Marriott Louisville East

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown, 9.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1000)
"Very nice hotel, rooms were clean and comfortable, breakfast is great!"
United States
Miguel
The price is S$166
includes taxes & fees
28 Dec - 29 Dec
Marriott Louisville East
Lobby
Fairfield Inn & Suites by Marriott Louisville Northeast

Fairfield Inn & Suites by Marriott Louisville Northeast

Fairfield Inn & Suites by Marriott Louisville Northeast
2.5 star property
12.6 km from Cherokee Seneca
9.2 out of 10, Wonderful, (614)
"Great place to stay! Very clean, comfortable bed, great breakfast with healthy options, and a nice fitness area. The staff were all polite and greeted us when we arrived and checked out. We will definitely stay here again"
United States
Brenda
The price is S$121
includes taxes & fees
1 Jan - 2 Jan, 2026
Fairfield Inn & Suites by Marriott Louisville Northeast
Indoor pool
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination
3.5 star property
20.2 km from Cherokee Seneca
8.2 out of 10, Very good, (1001)
"The room was very clean, the staff was very friendly and helpful."
United States
Judy
The price is S$150
includes taxes & fees
6 Jan - 7 Jan, 2026
Caesars Southern Indiana - A Caesars Rewards Destination
Exterior
Holiday Inn Express Hotel & Suites Louisville East by IHG

Holiday Inn Express Hotel & Suites Louisville East by IHG

Holiday Inn Express Hotel & Suites Louisville East by IHG
2.5 star property
Jeffersontown, 13.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (757)
"Very good breakfast and friendly staff. The room very spacious and very clean"
United States
Khanh
The price is S$126
includes taxes & fees
2 Jan - 3 Jan, 2026
Holiday Inn Express Hotel & Suites Louisville East by IHG
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1005)
"Great facility. Darrel at the front desk was great!"
United States
John
The price is S$144
includes taxes & fees
12 Jan - 13 Jan, 2026
Cambria Hotel Louisville Downtown-Whiskey Row
Terrace/patio
Hyatt House Louisville East

Hyatt House Louisville East

Hyatt House Louisville East
2.0 star property
9.2 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1004)
"Friendly people, pleasant all around stay. Excellent breakfast and night staff. Would definitely stay here again."
United States
Krista
The price is S$141
includes taxes & fees
29 Dec - 30 Dec
Hyatt House Louisville East
Exterior
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 6.9 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1000)
"The room was wonderful and the staff exceptional."
United States
Daniel
The price is S$155
includes taxes & fees
9 Jan - 10 Jan, 2026
Homewood Suites by Hilton Louisville Downtown, KY
Lobby
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North
2.5 star property
18.6 km from Cherokee Seneca
8.4 out of 10, Very good, (1008)
"Very clean and conveniently off interstate."
United States
Brady
The price is S$105
includes taxes & fees
28 Dec - 29 Dec
Ramada by Wyndham Sellersburg/Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.
Louisville showing street scenes and signage as well as a small group of people

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Conrad Caldwell House which includes heritage elements and signage

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Conrad-Caldwell House Museum while in the area.

Top Cherokee Seneca Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"Awesome place!"
Roy 5-night trip
Posted 2 days ago
Galt House Hotel Trademark Collection by Wyndham

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.

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