⭐ Top 10 Hotels Near Louisville Science Center for 2026

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.

A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

1. Louisville Bourbon Inn

Old Louisville, 2.9 km from Louisville Science Center

Roy

S$413

includes taxes & fees

28 Sept - 29 Sept

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A living room with a sofa, a fireplace, a staircase, and a chandelier.

A room with a red velvet sofa, a blue armchair, and a small round table with books.

An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

2. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Louisville Science Center

Casey

S$270

includes taxes & fees

28 Sept - 29 Sept

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

3. The Brown Hotel

Downtown Louisville, 1.2 km from Louisville Science Center

Melanie

S$213

includes taxes & fees

28 Sept - 29 Sept

A modern bar area with a circular bar, multiple seating options, and a large screen.

A modern lobby with a fireplace, seating area, and a reception desk.

A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.

A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

4. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Louisville Science Center

Cinda

S$179

includes taxes & fees

18 Oct - 19 Oct

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

A bar with shelves of liquor bottles and a bartender preparing drinks.

A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

5. Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Louisville Science Center

Adam

S$368

includes taxes & fees

4 Oct - 5 Oct

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A swimming pool with lounge chairs and a view of the city.

A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.

6. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Louisville Science Center

Diane

S$216

includes taxes & fees

12 Oct - 13 Oct

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.

A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

7. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Louisville Science Center

S$183

includes taxes & fees

4 Oct - 5 Oct

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

A building with a sign reading "THE GRADY" at the entrance.

8. The Grady

Downtown Louisville, 0.2 km from Louisville Science Center

Bruce

S$262

includes taxes & fees

11 Oct - 12 Oct

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

9. Stellar Suites

East Market District, 2.2 km from Louisville Science Center

Benton

S$212

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

A modern interior with a fireplace, bookshelves, and seating areas.

10. Omni Louisville Hotel

Downtown Louisville, 0.8 km from Louisville Science Center

S$419

includes taxes & fees

9 Oct - 10 Oct

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

11. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from Louisville Science Center

Matt

S$298

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

A modern hotel room with a large bed, a city view, and a unique headboard design.

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Louisville Science Center

Breeana

S$319

includes taxes & fees

29 Sept - 30 Sept

An outdoor seating area with wicker furniture and a fire pit.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

A modern lounge area with seating, tables, and a view of the city through large windows.

A modern living room with a sofa, armchairs, a coffee table, and a TV.

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Louisville Science Center

Scott

S$177

includes taxes & fees

18 Oct - 19 Oct

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.

14. AC Hotel Louisville Downtown

East Market District, 2.1 km from Louisville Science Center

Jen

S$215

includes taxes & fees

4 Oct - 5 Oct

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern living room with a sofa, ottomans, a coffee table, and a rug.

A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

15. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Bryan

S$192

includes taxes & fees

4 Oct - 5 Oct

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern bar area with sofas, tables, and a bar stocked with bottles.

A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

16. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Angela

S$197

includes taxes & fees

4 Oct - 5 Oct

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

A yellow coffee shop counter with a menu board above, displaying various coffee and food items.

A brightly lit grocery store with yellow shelving and a central checkout counter.

17. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Louisville Science Center

Rebekah

S$228

includes taxes & fees

4 Oct - 5 Oct

A covered patio with a stone wall, a glass table, and a bench.

A grand room with a fireplace, a staircase, and a chandelier.

A garden pathway with a lantern, potted plants, and a white fence.

18. Central Park Bed & Breakfast

Old Louisville, 3 km from Louisville Science Center

Angie

S$238

includes taxes & fees

29 Sept - 30 Sept

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

A balcony with a view of a river, a bridge, and a cityscape.

A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

19. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Louisville Science Center

Saud

S$244

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.

An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.

A hotel dining area with long tables, booths, and a bar.

20. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Maurica

S$245

includes taxes & fees

11 Oct - 12 Oct

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Compare popular hotels close to Louisville Science Center

Property	Property class	Guest rating
Louisville Bourbon Inn	10.0 Exceptional 25 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 147 reviews	View
The Brown Hotel	9.4 Exceptional 1,314 reviews	View
Cambria Hotel Louisville Downtown-Whiskey Row	9.4 Exceptional 1,009 reviews	View
Hotel Distil, Autograph Collection	9.6 Exceptional 505 reviews	View

Top Louisville Science Center Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent

"The directions for the parking could be a little more clear but we made it. Great location."

Holiday Inn Louisville Downtown by IHG

10/10 Excellent

"Great place highly recommend"

Radisson Hotel Louisville North

10/10 Excellent

"Great stay! Location was very convenient."

Omni Louisville Hotel

10/10 Excellent

"The check in/out was seamless, the valet was attentive and quick, the coffee shop in house was amazing, all staff we dealt with were extremely pleasant, and the pool/hot tub were phenomenal! 10/10 stay, would come again!"

The Brown Hotel

10/10 Excellent

"Classic clean and very historical"

Moxy Louisville Downtown

8/10 Good

"No way to get hot water for tea for guests."

Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent

"Great location. Nice property. Will use again."

Aloft by Marriott Louisville Downtown

10/10 Excellent

"Super easy to walk to a bunch of distilleries and also get to great restaurants and speakeasies."

Hyatt Regency Louisville

8/10 Good

"Was close to all activities walking distance"

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)

Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

Hotels near Louisville Science Center

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Our top choices for Louisville Science Center hotels

1. Louisville Bourbon Inn

2. DuPont Mansion Bed & Breakfast

3. The Brown Hotel

4. Cambria Hotel Louisville Downtown-Whiskey Row

5. Hotel Distil, Autograph Collection

6. Homewood Suites by Hilton Louisville Downtown, KY

7. Tempo By Hilton Louisville Downtown Nulu

8. The Grady

9. Stellar Suites

10. Omni Louisville Hotel

11. 21c Museum Hotel Louisville

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

13. Towneplace Suites By Marriott Louisville Downtown

14. AC Hotel Louisville Downtown

15. Moxy Louisville Downtown

16. Aloft by Marriott Louisville Downtown

17. Hotel Genevieve part of JdV by Hyatt

18. Central Park Bed & Breakfast

19. Galt House Hotel Trademark Collection by Wyndham

20. Embassy Suites Louisville Downtown

Compare popular hotels close to Louisville Science Center

Top Louisville Science Center Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Holiday Inn Louisville Downtown by IHG

Radisson Hotel Louisville North

Omni Louisville Hotel

The Brown Hotel

Moxy Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown

Hyatt Regency Louisville

Other attractions near Louisville Science Center

Louisville Slugger Museum

Muhammad Ali Center

Frazier International History Museum

Kentucky Center for the Performing Arts

Kentucky Museum of Art and Craft

Golden Statue of David

SAR Genealogical Research Library: NSSAR Library

Louisville Glassworks

Frequently asked questions