Madre de Dios Region Holidays

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    Save up to S$134 when you book a flight and hotel together*

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Top hotels in Madre de Dios Region

Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429 Tambopata Madre de Dios
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (19 reviews)
Great stay, friendly owners and staff.

Reviewed on 22 Jun, 2025

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Libelula Hotel
Inkaterra Reserva Amazonica

Inkaterra Reserva Amazonica

4 out of 5
Madre De Dios River Km. 15 Las Piedras Madre de Dios
9.2/10 Wonderful! (43 reviews)
World class!

Reviewed on 19 Oct, 2025

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Inkaterra Reserva Amazonica
Plaza Jungle Hostel

Plaza Jungle Hostel

1 out of 5
229 Arequipa Puerto Maldonado Madre de Dios
Fully refundableReserve now, pay when you stay
The price is S$38 per night from 19 Nov to 20 Nov
S$38
19 Nov - 20 Nov
Plaza Jungle Hostel
See all 56 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Madre de Dios Region holiday package cost?
Choose from any combination of hotels, flights and car rentals, and you can be holidaying in Madre de Dios Region from just . And the more you bundle, the more money you save. The getaway of your dreams has never been more affordable.
How do I get a cheap travel package to Madre de Dios Region?
Browse and book everything all in one place with our Madre de Dios Region holiday packages. We have incredible bargains on hotels, flights and more that'll keep your pocket happy and your sense of adventure alive. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, you'll have endless opportunities to mix and match as you please.
What are the top hotels in Madre de Dios Region?
For properties in Tambopata with friendly service and cosy beds, you can't beat Kapievi Ecovillage and Inkaterra Reserva Amazonica. If you plan to explore Las Piedras as well, you'll get a solid night's sleep at Copasu Hotel or Tarantula Hostel.
How far in advance should I book my Madre de Dios Region holiday?
Reward yourself with the biggest variety and the lowest prices by booking your holiday to Madre de Dios Region nice and early. Airlines generally advertise flight tickets around 12 months prior to departure, so reserve your spot ASAP. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream holiday!
What does an Expedia Madre de Dios Region travel package include?
Hotels, flights and car rentals — we connect you to the very best bargains. All you have to do is decide on your favourite combination. After you've made your booking, you can add on the fun stuff like sightseeing activities. Our travel packages make it easy to create an awesome Madre de Dios Region getaway.
What should I know before booking a Madre de Dios Region travel package?
When you book your flights, hotels and car rentals together, you'll enjoy amazing discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a cosy apartment in the city, Expedia will help make it happen.
Can I choose my airline with a Madre de Dios Region Expedia holiday package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Madre de Dios Region holiday package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can cancel or change your Madre de Dios Region holiday package. If you booked in the last 24 hours, you may be entitled to a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to find out more.

What to do in Madre de Dios Region

From Puerto Maldonado: Tambopata National Reserve 3-Day Tour

From Puerto Maldonado: Tambopata National Reserve 3-Day Tour

S$362
per adult
From Puerto Maldonado: Tambopata National Reserve 3-Day Tour
Monkey island

3 days 2 nights - Tambopata Jungle

S$585
per adult
3 days 2 nights - Tambopata Jungle
Puerto Maldonado: 4-Day Tambopata Rainforest Tour

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

S$578
per adult
Puerto Maldonado: 4-Day Tambopata Rainforest Tour
See all activities in Madre de Dios Region

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.