⭐ Top 10 Hotels Near Mark Twain Boyhood Home and Museum for 2026

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Our top choices for Mark Twain Boyhood Home and Museum hotels

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A compact kitchen with a refrigerator, microwave, and sink.

A historic building with a stone facade and multiple windows, featuring a sign about Tom Sawyer's fence.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

1. Riverside Inn Hannibal

0.2 km from Mark Twain Boyhood Home and Museum

Janee

S$266

includes taxes & fees

6 Oct - 7 Oct

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

2. Best Western On The River

< 0.1 km from Mark Twain Boyhood Home and Museum

Raymond

S$162

includes taxes & fees

6 Oct - 7 Oct

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

A swimming pool with lounge chairs and a covered seating area.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

3. Lighthouse Inn & Suites

0.6 km from Mark Twain Boyhood Home and Museum

Kari

S$279

includes taxes & fees

6 Oct - 7 Oct

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

4. Garden House Bed and Breakfast

0.3 km from Mark Twain Boyhood Home and Museum

Edward

S$117

includes taxes & fees

5 Nov - 6 Nov

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

5. Motel 6 Hannibal, MO

2.9 km from Mark Twain Boyhood Home and Museum

Donna B

S$86

includes taxes & fees

7 Oct - 8 Oct

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

6. Super 8 by Wyndham Hannibal

3 km from Mark Twain Boyhood Home and Museum

Betty

S$91

includes taxes & fees

6 Oct - 7 Oct

A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

A bedroom with a brick wall, wooden beams, a bed, two sofas, and a small table with a lamp.

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a trash bin.

A rustic living room with exposed brick walls, wooden beams, and a cozy fireplace. There are two leather sofas with throw pillows and a fluffy rug.

7. Deck + River View: Loft in Downtown Hannibal

0.1 km from Mark Twain Boyhood Home and Museum

S$339

includes taxes & fees

7 Oct - 8 Oct

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

8. Sleep Inn & Suites Hannibal West

6.6 km from Mark Twain Boyhood Home and Museum

Patricia

S$159

includes taxes & fees

2 Nov - 3 Nov

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel entrance with a central fountain, large columns, and a clear sky.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

9. Quality Inn & Suites Hannibal West

6.4 km from Mark Twain Boyhood Home and Museum

Gayle

S$113

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a sofa, a desk, and a lamp.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

10. Comfort Inn & Suites - Hannibal

4.7 km from Mark Twain Boyhood Home and Museum

Jerry

S$112

includes taxes & fees

11 Oct - 12 Oct

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

A hotel room with two beds, a desk, a lamp, a painting, and a carpet.

A hotel with a covered entrance, a parking lot, and a clear sky.

11. Days Inn by Wyndham Hannibal

4.9 km from Mark Twain Boyhood Home and Museum

Christian

S$88

includes taxes & fees

1 Nov - 2 Nov

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A hotel room with two beds, a desk, a chair, and a telephone.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

12. Howard Johnson BY Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

Debbie

S$87

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

A gym with cardio equipment, mirrored walls, and a view of a Pepsi store outside.

13. Baymont by Wyndham Hannibal

5 km from Mark Twain Boyhood Home and Museum

brian

S$82

includes taxes & fees

8 Oct - 9 Oct

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Compare popular hotels close to Mark Twain Boyhood Home and Museum

Property	Property class	Guest rating
Riverside Inn Hannibal	9.6 Exceptional 201 reviews	View
Best Western On The River	8.8 Excellent 1,008 reviews	View
Lighthouse Inn & Suites	8.8 Excellent 47 reviews	View
Garden House Bed and Breakfast	8.4 Very good 53 reviews	View
Motel 6 Hannibal, MO	7.4 Good 1,001 reviews	View

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Holiday Inn Quincy East by IHG

10/10 Excellent

"This is my second time staying here and I absolutely love it. It’s clean and quiet. The room is beautiful. The staff are so nice. What more can you ask for."

Baymont by Wyndham Hannibal

8/10 Good

"Literally my only complaint would be the breakfast was a scoop of eggs and gravy. Everything was out and the drink cups were micro sized. The rooms were nice and clean"

Heritage Hotel Quincy

10/10 Excellent

"The rooms are newly renovated."

Sleep Inn & Suites Hannibal West

10/10 Excellent

"Staff were nice and the room was clean. This was an overnight stay for us as we made our way from Minnesota to Tennessee."

Riverside Inn Hannibal

10/10 Excellent

"Beautiful view of the river! Easy access to downtown and shops/restaurants. The jacuzzi was wonderful and a nice bonus! We’ll definitely stay there again if we’re back in the area."

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

10/10 Excellent

"Clean room"

Quality Inn & Suites Hannibal West

10/10 Excellent

"Breakfast buffet was arranged very well."

Stoney Creek Inn Quincy

10/10 Excellent

"It has a rustic feel to it but is very clean and nice."

Comfort Inn & Suites - Hannibal

10/10 Excellent

"Rooms were clean. Staff was friendly."

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savour the top-notch restaurants.

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Planters Barn Theater

8.8/10 (22 reviews)

Get tickets for a show at Planters Barn Theater, a popular theatre in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your holiday in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Bluff City Theater

7.6/10 (5 reviews)

Get tickets for a show at Bluff City Theater, a theatre with a story to tell in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Molly Brown Museum and Home

8.4/10 (64 reviews)

You can browse the exhibits at Molly Brown Museum and Home, a museum with a story of its own, during your holiday in Hannibal. While in this walkable area, you can savour the top-notch restaurants.

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Lovers Leap

8.8/10 (171 reviews)

Find out about the history of Hannibal when you spend time at Lovers Leap. While in this walkable area, you can savour the top-notch restaurants.

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Riverview Park

You can find out about the history of Hannibal when you stop by Riverview Park. While in this family-friendly area, you can savour the top-notch restaurants.

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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.

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Frequently asked questions

What's the area like around Mark Twain Boyhood Home and Museum?

Mark Twain Boyhood Home and Museum is located in a welcoming area of Hannibal known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 40 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to Mark Twain Boyhood Home and Museum?

Adjacent to Mark Twain Boyhood Home and Museum, Best Western On The River is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices close by include Lighthouse Inn & Suites and Garden House Bed and Breakfast.

How many hotels will I find near Mark Twain Boyhood Home and Museum?

Expedia has 40 hotels and other accommodation options within a mile from Mark Twain Boyhood Home and Museum.

If I need to cancel the hotel reservation for my stay near Mark Twain Boyhood Home and Museum, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Mark Twain Boyhood Home and Museum.

What can I see and do near Mark Twain Boyhood Home and Museum?

You'll want to browse the exhibits at Jim's Journey: The Huck Finn Freedom Center and Molly Brown Museum and Home. Mark Twain Memorial Lighthouse, Rockcliffe Mansion and Mark Twain Cave are notable landmarks to explore if you're in the area. You can enjoy live performances at Bluff City Theater and Planters Barn Theater.

Hotels near Mark Twain Boyhood Home and Museum

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mark Twain Boyhood Home and Museum hotels

1. Riverside Inn Hannibal

2. Best Western On The River

3. Lighthouse Inn & Suites

4. Garden House Bed and Breakfast

5. Motel 6 Hannibal, MO

6. Super 8 by Wyndham Hannibal

7. Deck + River View: Loft in Downtown Hannibal

8. Sleep Inn & Suites Hannibal West

9. Quality Inn & Suites Hannibal West

10. Comfort Inn & Suites - Hannibal

11. Days Inn by Wyndham Hannibal

12. Howard Johnson BY Wyndham Hannibal

13. Baymont by Wyndham Hannibal

Compare popular hotels close to Mark Twain Boyhood Home and Museum

Top Mark Twain Boyhood Home and Museum Hotel Reviews

Holiday Inn Quincy East by IHG

Baymont by Wyndham Hannibal

Heritage Hotel Quincy

Sleep Inn & Suites Hannibal West

Riverside Inn Hannibal

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area

Quality Inn & Suites Hannibal West

Stoney Creek Inn Quincy

Comfort Inn & Suites - Hannibal

Other attractions near Mark Twain Boyhood Home and Museum

Mark Twain Memorial Lighthouse

Planters Barn Theater

Jim's Journey: The Huck Finn Freedom Center

Bluff City Theater

Molly Brown Museum and Home

Lovers Leap

Riverview Park

Sodalis Nature Preserve

Frequently asked questions

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