Hotels in Medical District

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical District hotels

Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown
2.0 star property
Medical District
5.6 out of 10, (1008)
"Room was clean and smelled fresh/sanitized. Hotel is well gated and secured"
United States
Antonio
The price is S$77
includes taxes & fees
17 Dec - 18 Dec
Motel 6 Memphis, TN - Downtown

Capital O Kings Inn

Capital O Kings Inn
2.5 star property
Medical District
5.6 out of 10, (28)
"No room service for an entire week, Will never stay there again. "
United States
Ian
The price is S$78
includes taxes & fees
21 Dec - 22 Dec
Capital O Kings Inn

Comfort Inn Horn Lake - Southhaven

Comfort Inn Horn Lake - Southhaven
2.5 star property
19.4 km from Medical District
8.2 out of 10, Very good, (604)
"Ideal place for a short stay. I was very pleased!"
United States
Kenya
The price is S$123
includes taxes & fees
26 Dec - 27 Dec
Comfort Inn Horn Lake - Southhaven

Sleep Inn Horn Lake - Southaven

Sleep Inn Horn Lake - Southaven
2.5 star property
19.8 km from Medical District
7.6 out of 10, Good, (687)
"The stay was very good. Room was clean. Nice location with a lot of amenties in the area. Clean and quiet location. "
Canada
Michael
The price is S$106
includes taxes & fees
11 Jan - 12 Jan, 2026
Sleep Inn Horn Lake - Southaven

Wingate by Wyndham Horn Lake Southaven

Wingate by Wyndham Horn Lake Southaven
2.0 star property
20 km from Medical District
7.4 out of 10, Good, (575)
"yes , yes , yes would gladly stay again "
United States
Starla
The price is S$109
includes taxes & fees
28 Dec - 29 Dec
Wingate by Wyndham Horn Lake Southaven

Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven
3.0 star property
20 km from Medical District
9.2 out of 10, Wonderful, (1007)
"Friendly staff, clean room, happy hour food & drink"
United States
Kathleen
The price is S$143
includes taxes & fees
20 Dec - 21 Dec
Drury Inn & Suites Memphis Southaven

Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland

Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland
2.0 star property
19.7 km from Medical District
8.4 out of 10, Very good, (596)
"Quiet and nice are. The hotel is close to many food and shopping places. The breakfast wasn’t what we expected. No eggs, meat, nor grits. "
United States
Ashley
The price is S$129
includes taxes & fees
21 Dec - 22 Dec
Days Inn & Suites by Wyndham Horn Lake/Memphis Graceland

Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria
3.0 star property
Wolfchase, 22.4 km from Medical District
9.0 out of 10, Wonderful, (1377)
"Great breakfast selection, cleanliness "
United States
JACQUE
The price is S$145
includes taxes & fees
23 Dec - 24 Dec
Hyatt Place Memphis/Wolfchase Galleria

Best Western Plus Galleria Inn & Suites

Best Western Plus Galleria Inn & Suites
2.5 star property
Wolfchase, 24.6 km from Medical District
8.0 out of 10, Very good, (1004)
"Very nice place to stay."
United States
Jack
The price is S$114
includes taxes & fees
21 Dec - 22 Dec
Best Western Plus Galleria Inn & Suites

Homestay Horn Lake / Southaven MS

Homestay Horn Lake / Southaven MS
2.5 star property
20 km from Medical District
7.2 out of 10, Good, (995)
"It had everything I needed and was super clean and spacious "
United States
Christopher Earl James
The price is S$96
includes taxes & fees
14 Jan - 15 Jan, 2026
Homestay Horn Lake / Southaven MS

Hilton Garden Inn Memphis/Wolfchase Galleria

Hilton Garden Inn Memphis/Wolfchase Galleria
3.0 star property
22.1 km from Medical District
8.2 out of 10, Very good, (1008)
"Love that hotel "
United States
Sherkenna
The price is S$131
includes taxes & fees
4 Jan - 5 Jan, 2026
Hilton Garden Inn Memphis/Wolfchase Galleria

Fairfield Inn & Suites By Marriott Memphis Germantown

Fairfield Inn & Suites By Marriott Memphis Germantown
2.5 star property
27.1 km from Medical District
8.2 out of 10, Very good, (1002)
"Nina and Jam were exceptional at the front desk. Everything was clean and well kept. Really enjoyed the stay"
United States
Roy
The price is S$144
includes taxes & fees
19 Dec - 20 Dec
Fairfield Inn & Suites By Marriott Memphis Germantown

Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

Holiday Inn Express Hotel & Suites Memphis Southwind by IHG
3.0 star property
Southwind, 24.3 km from Medical District
8.4 out of 10, Very good, (1019)
"i enjoyed my stay!"
United States
Christopher
The price is S$103
includes taxes & fees
1 Jan - 2 Jan, 2026
Holiday Inn Express Hotel & Suites Memphis Southwind by IHG

Hu. Hotel

Hu. Hotel
3.5 star property
Downtown Memphis, 1.9 km from Medical District
8.4 out of 10, Very good, (1620)
"Great hotel and location "
United States
Holiday
The price is S$140
includes taxes & fees
22 Dec - 23 Dec
Hu. Hotel

Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG

Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG
3.0 star property
Wolfchase, 24 km from Medical District
8.8 out of 10, Excellent, (1000)
"Room was clean and the staff was friendly."
United States
Brenda
The price is S$145
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Hotel & Suites Memphis - Wolfchase Galleria by IHG

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown
2.5 star property
Downtown Memphis, 1.9 km from Medical District
8.8 out of 10, Excellent, (1008)
"Great hotel "
United States
Andre
The price is S$134
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn Memphis Downtown

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland
3.0 star property
8.4 km from Medical District
7.4 out of 10, Good, (2208)
"Room was clean the stay was very pleasant"
United States
Tammy
The price is S$82
includes taxes & fees
21 Dec - 22 Dec
La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

Hyatt Place Memphis/Germantown

Hyatt Place Memphis/Germantown
3.0 star property
27.2 km from Medical District
9.0 out of 10, Wonderful, (1004)
"clean room and great staff"
United States
Martha
The price is S$141
includes taxes & fees
28 Dec - 29 Dec
Hyatt Place Memphis/Germantown

Hampton Inn & Suites Memphis Germantown

Hampton Inn & Suites Memphis Germantown
2.5 star property
21.2 km from Medical District
9.2 out of 10, Wonderful, (1004)
"Staff was incredibly friendly, and the breakfast was delicious."
United States
John
The price is S$214
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Memphis Germantown

Big Cypress Lodge

Big Cypress Lodge
5.0 star property
Pinch District, 2.4 km from Medical District
9.0 out of 10, Wonderful, (1718)
"The lodge was amazing, we will be back soon."
United States
Carl
The price is S$379
includes taxes & fees
12 Jan - 13 Jan, 2026
Big Cypress Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical District

Find the best Medical District areas for the activities you enjoy most.

Downtown Memphis

Downtown Memphis is a destination visitors seek out for its ample dining options, fascinating museums and great live music. You might also want to check out attractions like Statue of Elvis or Orpheum Theatre while you're exploring the neighbourhood.

East Memphis

Travellers to East Memphis praise its popular shops. If you've got some more time to explore, be sure to stop by Leftwich Tennis Center and Theatre Memphis.

Midtown

Theatres, live music and museums are some highlights of Midtown. Make a stop by Minglewood Hall or Memphis Brooks Museum of Art while you're exploring.

Whitehaven

The ample dining options and great live music are top of the list for many visitors to Whitehaven. A stop by Graceland or Tri-State Bank of Memphis might round out your trip.

North Memphis

Visitors to North Memphis like its bars and churches, and Burkle Estate is a sight worth a stop.

Top Medical District Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Medical District?
Travellers will be sure to enjoy their time in Memphis's Medical District neighbourhood. Are you looking for Medical District travel tips? Make sure that you visit Sun Studio and Hunt-Phelan Home while you're in the neighbourhood.
What's the best accommodation in Medical District?
Expedia customers rank Motel 6 Memphis, TN - Downtown the highest for a stay in Medical District.
How many hotels can I expect to find in Medical District?
When you want to put your feet up after a day of exploring the sights in Memphis, you can choose from 17 Expedia hotels and other accommodation options in Medical District.
If I need to cancel my hotel reservation in Medical District, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best deals available in Medical District.
What are the top things to see and do in Medical District?
Some landmarks in Medical District that you won't want to miss include Sun Studio, Hunt-Phelan Home and NAACP Memphis. Woodruff-Fontaine House and Mallory-Neely House are also worth a visit when you're out sightseeing in Memphis.