Hotels in Medicine Lake

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Our top choices for Medicine Lake hotels

Holiday Inn Express & Suites Mall of America - MSP Airport by IHG

Holiday Inn Express & Suites Mall of America - MSP Airport by IHG
2.5 star property
19.9 km from Medicine Lake
9.0 out of 10, Wonderful, (2898)
"Great place to stay!!! "
United States
Tamera
The price is S$125
includes taxes & fees
1 Jan - 2 Jan, 2026
Holiday Inn Express & Suites Mall of America - MSP Airport by IHG

Hilton Garden Inn Minneapolis Airport Mall of America

Hilton Garden Inn Minneapolis Airport Mall of America
3.5 star property
20.3 km from Medicine Lake
8.4 out of 10, Very good, (2191)
"Great staff great rooms "
United States
Mathew
The price is S$108
includes taxes & fees
25 Jan - 26 Jan, 2026
Hilton Garden Inn Minneapolis Airport Mall of America

Hilton Minneapolis

Hilton Minneapolis
4.0 star property
11.8 km from Medicine Lake
8.8 out of 10, Excellent, (1009)
"It was a nice stay "
Canada
Shannon
The price is S$149
includes taxes & fees
26 Jan - 27 Jan, 2026
Hilton Minneapolis

The Lofton Hotel, Tapestry Collection by Hilton

The Lofton Hotel, Tapestry Collection by Hilton
4.5 star property
11.6 km from Medicine Lake
9.4 out of 10, Exceptional, (1004)
"Friendly staff, comfortable beds, beautiful views, great location "
United States
Julia
The price is S$172
includes taxes & fees
9 Jan - 10 Jan, 2026
The Lofton Hotel, Tapestry Collection by Hilton

Hyatt Regency Bloomington - Minneapolis

Hyatt Regency Bloomington - Minneapolis
4.0 star property
21.9 km from Medicine Lake
9.0 out of 10, Wonderful, (2072)
"Clean room, great breakfast, convenient "
United States
Joanne
The price is S$133
includes taxes & fees
31 Dec - 1 Jan, 2026
Hyatt Regency Bloomington - Minneapolis

The Marquette Hotel, Curio Collection by Hilton

The Marquette Hotel, Curio Collection by Hilton
4.0 star property
11.9 km from Medicine Lake
9.4 out of 10, Exceptional, (1004)
"Clean, helpful staff and location. "
United States
Sheena Martina
The price is S$161
includes taxes & fees
6 Jan - 7 Jan, 2026
The Marquette Hotel, Curio Collection by Hilton

Hampton Inn & Suites Minneapolis / Downtown

Hampton Inn & Suites Minneapolis / Downtown
3.0 star property
11.5 km from Medicine Lake
9.4 out of 10, Exceptional, (1937)
"Courteous staff and great location. "
United States
Darren
The price is S$115
includes taxes & fees
5 Jan - 6 Jan, 2026
Hampton Inn & Suites Minneapolis / Downtown

Hampton Inn & Suites Minneapolis University Area

Hampton Inn & Suites Minneapolis University Area
2.5 star property
16.3 km from Medicine Lake
9.4 out of 10, Exceptional, (1004)
"Everything was very efficient at check in, nice place"
United States
Michael
The price is S$117
includes taxes & fees
6 Jan - 7 Jan, 2026
Hampton Inn & Suites Minneapolis University Area

Fairfield Inn & Suites by Marriott Minneapolis Shakopee

Fairfield Inn & Suites by Marriott Minneapolis Shakopee
2.5 star property
24.1 km from Medicine Lake
9.0 out of 10, Wonderful, (766)
"The desk clerk was very friendly, polite and responsive. Love staying here."
United States
Craig
The price is S$121
includes taxes & fees
1 Jan - 2 Jan, 2026
Fairfield Inn & Suites by Marriott Minneapolis Shakopee

Embassy Suites by Hilton Minneapolis Airport

Embassy Suites by Hilton Minneapolis Airport
4.0 star property
21.9 km from Medicine Lake
9.0 out of 10, Wonderful, (1869)
"Great place to stay!"
United States
Rhonda
The price is S$155
includes taxes & fees
4 Jan - 5 Jan, 2026
Embassy Suites by Hilton Minneapolis Airport

Hyatt Place Minneapolis Downtown

Hyatt Place Minneapolis Downtown
3.0 star property
12.4 km from Medicine Lake
8.4 out of 10, Very good, (2074)
"excellent fast check in, room is great. Very nice hotel"
Canada
Rob
The price is S$149
includes taxes & fees
8 Jan - 9 Jan, 2026
Hyatt Place Minneapolis Downtown

The Royal Sonesta Minneapolis Downtown

The Royal Sonesta Minneapolis Downtown
4.5 star property
11.7 km from Medicine Lake
9.0 out of 10, Wonderful, (1782)
"Beautiful hotel, great staff! "
United States
Katie
The price is S$166
includes taxes & fees
16 Jan - 17 Jan, 2026
The Royal Sonesta Minneapolis Downtown

Sheraton Minneapolis Downtown Convention Center

Sheraton Minneapolis Downtown Convention Center
3.5 star property
11.6 km from Medicine Lake
8.8 out of 10, Excellent, (123)
"Very nice rooms and convenient location "
United States
Tiffany
The price is S$164
includes taxes & fees
31 Dec - 1 Jan, 2026
Sheraton Minneapolis Downtown Convention Center

Baymont by Wyndham Bloomington MSP Airport

Baymont by Wyndham Bloomington MSP Airport
2.5 star property
19.8 km from Medicine Lake
8.0 out of 10, Very good, (2098)
"Great stay and great hotel!"
United States
Dillon
The price is S$92
includes taxes & fees
26 Jan - 27 Jan, 2026
Baymont by Wyndham Bloomington MSP Airport

The Westin Minneapolis

The Westin Minneapolis
4.0 star property
11.9 km from Medicine Lake
8.2 out of 10, Very good, (1004)
"Always a great stay at the Westin! "
United States
gabby
The price is S$164
includes taxes & fees
30 Dec - 31 Dec
The Westin Minneapolis

Hyatt Regency Minneapolis

Hyatt Regency Minneapolis
4.0 star property
11.6 km from Medicine Lake
8.8 out of 10, Excellent, (1005)
"Everything excellent there. "
United States
Franklin
The price is S$153
includes taxes & fees
4 Jan - 5 Jan, 2026
Hyatt Regency Minneapolis

Hampton Inn by Hilton Minneapolis/Eagan

Hampton Inn by Hilton Minneapolis/Eagan
2.5 star property
26.7 km from Medicine Lake
8.8 out of 10, Excellent, (1008)
"Great staff…great place!"
United States
Mark
The price is S$139
includes taxes & fees
4 Jan - 5 Jan, 2026
Hampton Inn by Hilton Minneapolis/Eagan

Hampton Inn & Suites Downtown St. Paul

Hampton Inn & Suites Downtown St. Paul
2.5 star property
25.6 km from Medicine Lake
9.4 out of 10, Exceptional, (1037)
"Good Location to stay as always!"
United States
Josh
The price is S$161
includes taxes & fees
7 Jan - 8 Jan, 2026
Hampton Inn & Suites Downtown St. Paul

Fairfield Inn & Suites By Marriott Minneapolis Downtown

Fairfield Inn & Suites By Marriott Minneapolis Downtown
2.5 star property
11.3 km from Medicine Lake
9.0 out of 10, Wonderful, (1475)
"Friendly staff, nice room, comfy bed."
United States
david
The price is S$129
includes taxes & fees
5 Jan - 6 Jan, 2026
Fairfield Inn & Suites By Marriott Minneapolis Downtown

Hyatt House Mall Of America Msp Airport

Hyatt House Mall Of America Msp Airport
2.5 star property
22 km from Medicine Lake
8.6 out of 10, Excellent, (1721)
"Amazing rooms and top notch breakfast!! Will definitely stay again when in the area!!"
United States
Mariel
The price is S$145
includes taxes & fees
10 Jan - 11 Jan, 2026
Hyatt House Mall Of America Msp Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medicine Lake

Find the best Medicine Lake areas for the activities you enjoy most.

Downtown Minneapolis

Known for its fantastic nightlife and popular shops, there's plenty to explore in Downtown Minneapolis. Check out top attractions like Nicollet Mall and Foshay Tower, and jump on the metro at Nicollet Mall Station or Warehouse - Hennepin Station to see more of the city.

Downtown St. Paul

Travellers choose Downtown St. Paul for its great live music. Hop aboard the metro at 10th Street Station or Central Station and check out top sights like Fitzgerald Theater.

South Minneapolis

While you're in South Minneapolis, take in top sights like Parkway Theater or Lake Nokomis, and hop on the metro to see more of the city at 38th Street Station or 46th Street Station.

Downtown West

Enjoy the popular shops in Downtown West. Nicollet Mall is a worthwhile stop, and you can jump on the metro at Nicollet Mall Station or Government Plaza Station to see more of Minneapolis.

South Loop

While you're in South Loop, take in top sights like Mall of America or Sea Life Minnesota Aquarium, and hop on the metro to see more of the city at 28th Avenue Station or Mall of America Station.

Top Medicine Lake Hotel Reviews

Frequently asked questions

What is Medicine Lake like?
Travellers are sure to enjoy a stay in Plymouth's Medicine Lake neighbourhood.
If I need to cancel my hotel reservation in Medicine Lake, will I receive a refund?
Yes, most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals in Medicine Lake.
What can I see and do in this Plymouth neighbourhood?
A few places to visit in the area around Medicine Lake include French Park Beach, Sky Zone Indoor Trampoline Park and Plymouth Playhouse. When you're sightseeing in Plymouth, Brookview Golf Course and Ridgedale Center are also worth a stop.

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