Mesopotamia Holidays

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Things to do in Mesopotamia

In Mesopotamia, Argentina, visitors can indulge in birdwatching, hiking, and exploring the diverse wildlife. Essential activities include embarking on a Mesopotamia tour to uncover the region's ancient history, participating in various cultural rituals, and enjoying festive processions that showcase local traditions. These experiences offer a unique insight into the rich cultural tapestry of this captivating area.

Shopping

A short stroll from the city centre, you'll discover the vibrant shopping scene at Shopping Sur, offering a mix of local crafts and international brands. For a more authentic experience, head to the Mercado de Posadas, where you can find unique souvenirs and traditional Argentine products.

Recreation

Experience rejuvenation at serene spas offering thermal baths and holistic treatments. Engage in yoga sessions surrounded by nature, explore lush landscapes, and partake in mindfulness workshops. Indulge in local cuisine while enjoying tranquil river views, creating a harmonious blend of relaxation and cultural immersion in Mesopotamia.

Adventure

Explore the captivating Iguazu Falls, where you can take exhilarating boat rides and hike through lush rainforest trails. Experience the rich biodiversity at the Iberá Wetlands, perfect for kayaking, birdwatching, and spotting wildlife in their natural habitat.

Nightlife

The nightlife in Mesopotamia is vibrant, with lively bars and clubs. Enjoy a cocktail at La Cabaña, renowned for its atmosphere, or dance the night away at Club del Río, where local music creates an unforgettable experience.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Mesopotamia

Mesopotamia, Argentina, offers a wealth of attractions, particularly for those seeking scenic outdoor adventures. Explore the stunning national parks while discovering the rich history of numerous Mesopotamian gods and the vibrant festivals of ancient Mesopotamia. Experience the legacy of the ancient Mesopotamians as you immerse yourself in the local culture and natural beauty that surrounds this unique destination.

  • Portal Carambola: Enjoy breathtaking scenery and immerse yourself in outdoor adventures at this national park, located 22.5km from Mesopotamia. Explore its diverse landscapes and engage in thrilling activities amidst nature’s beauty.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.700000000000003°C)Light RainSunnyModerately HighAverage
February77.7°F (25.4°C)Light RainMostly Sunny
March72.9°F (22.700000000000003°C)Light RainMostly SunnyModerately HighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageAverage
November72.3°F (22.4°C)Light RainSunnyModerately HighAverage
December77.0°F (25.0°C)Light RainSunnyAverageSlightly High

Tips to save on your trip to Mesopotamia

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling during the off-peak season (typically ) for more affordable package holidays to Mesopotamia.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Top hotels in Mesopotamia

O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

2.5 out of 5
115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
The price is S$55 per night from 1 Feb to 2 Feb
S$55
1 Feb - 2 Feb
7.6/10 Good! (69 reviews)
La limpieza de los cuartos necesita mejorar. También agregar servicios básicos como TV y teléfono en los cuartos

Reviewed on 12 Mar, 2025

O2 Hotel Gualeguaychú
Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
The price is S$169 per night from 5 Feb to 6 Feb
S$169
5 Feb - 6 Feb
9.8/10 Exceptional! (20 reviews)
Excelente

Reviewed on 21 Jan, 2026

Marriott Corrientes Hotel
Hathor Concordia

Hathor Concordia

3 out of 5
Ruta Nacional 14-km 264.5 Concordia Entre Rios
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (364 reviews)
The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional".

Reviewed on 5 Dec, 2025

Get rates
Hathor Concordia
See all 497 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Parque Nacional El Palmar, Entre Rios, Argentina.

El Palmar National Park

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

El Palmar National Park

Victoria Beach

If a restful holiday is part of your travel plans, Victoria Beach might be the perfect place to visit during your trip to Victoria. Make some time to visit the monuments while you're in the area.

Victoria Beach

Agraciada Beach

Why not spend a care-free afternoon at Agraciada Beach during your travels in Nueva Palmira?

Agraciada Beach

Frequently asked questions

Can I cancel my flight booking to Mesopotamia due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our Customer Service Portal. It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Mesopotamia that have flexible change policies?
Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia.
What are some of the general tips for travellers to Mesopotamia during the COVID-19 outbreak?
If it's your first time travelling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one:
  • Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening.
  • Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening.
  • Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Mesopotamia?
Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway.
How can I find cheap tickets to Mesopotamia?
One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal.
How much is a flight to Mesopotamia?
You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just .
What are the most popular airports to fly into in Mesopotamia?
Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month.
When is the cheapest time to fly to Mesopotamia?
Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Mesopotamia?
Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal.
Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples:
  • Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.
  • LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.