Hotels near National Medical Center

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Check prices for these dates

Tonight
11 Nov - 12 Nov
Tomorrow
12 Nov - 13 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for National Medical Center (Siglo XXI) hotels

A building with ornate tiled facades, arched windows, and a balcony with a wrought iron railing.

1. Casa Talavera by Tasman

Casa Talavera by Tasman
2.5 star property
Roma Norte, 1.5 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (10 reviews)
"This was a great boutique hotel, staff was helpful, stayed in the cobalto suite which was clean and luxurious, they had pottery which they sell as souvenirs, we didn’t try the restaurant but it looked very nice, would stay here again."
United States
Saahir
The price is S$420
includes taxes & fees
30 Nov - 1 Dec
Casa Talavera by Tasman
A courtyard with a staircase leading to a second floor, surrounded by potted plants and a large hedge.

2. Casa Seis Siete

Casa Seis Siete
3.0 star property
Roma Norte, 1.3 km from National Medical Center (Siglo XXI)
10.0 out of 10, Exceptional, (67 reviews)
"Perfect location to stay for your time in CDMX. Easily walkable to public transportation as well as things to do and see in Roma Norte and Condessa. The staff go over the top to welcome you and make you feel at home. Breakfast is amazing as well. One of the favorite places I’ve ever stayed"
United States
Jennifer
The price is S$455
includes taxes & fees
7 Dec - 8 Dec
Casa Seis Siete
A courtyard with outdoor seating, a stone wall, and a variety of plants.

3. Casa Bamboo

Casa Bamboo
2.0 star property
1.2 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (18 reviews)
"Close yo my Family, very reasonably priced!"
United States
John
The price is S$60
includes taxes & fees
17 Nov - 18 Nov
Casa Bamboo
A narrow alley with brick walls, potted plants, and a tree trunk.

4. Taá Guesthouse

Taá Guesthouse
4.0 star property
Roma Norte, 1.3 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (9 reviews)
"I enjoyed my stay and would highly recommend it, particularly if you are looking for something more interesting than chain hotels!"
United States
Jacob
The price is S$188
includes taxes & fees
7 Dec - 8 Dec
Taá Guesthouse
A rooftop pool with lounge chairs and potted plants, overlooking a cityscape.

5. Xoma Boutique Stays by Viadora

Xoma Boutique Stays by Viadora
4.0 star property
Roma Norte, 1 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (260 reviews)
"Lovely place. Really good value for the location and amenities. Would stay there again for sure."
Canada
Paul
The price is S$550
includes taxes & fees
7 Dec - 8 Dec
Xoma Boutique Stays by Viadora
A modern hotel room with a wooden ceiling, two beds, a desk, and a view of greenery through large windows.

6. Colima 71 Casa de Arte Hotel

Colima 71 Casa de Arte Hotel
3.0 star property
Roma Norte, 1.4 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (54 reviews)
"This was by far the coolest hotel in the best location with the best staff and ambiance"
United States
Bobbi
The price is S$833
includes taxes & fees
16 Nov - 17 Nov
Colima 71 Casa de Arte Hotel
A modern interior with a wooden floor, a bed, a sofa, and a dining table.

7. La Valise Mexico City, Member of Small Luxury Hotels

La Valise Mexico City, Member of Small Luxury Hotels
5.0 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.8 out of 10, Exceptional, (56 reviews)
"I can’t recommend the hotel enough. The rooms were very clean and the staff was very attentive. They helped us every step of the way. The location was also very central and the breakfast was amazing. The projectors were fun to use."
United States
Brandon
The price is S$1,082
includes taxes & fees
15 Nov - 16 Nov
La Valise Mexico City, Member of Small Luxury Hotels
A rooftop terrace with outdoor seating, a pergola, and a city view.

8. ULIV Pulse Roma - Condesa

ULIV Pulse Roma - Condesa
4.5 star property
Roma Sur, 1.7 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (1,062 reviews)
"Great location, shopping, restaurants, parks."
United States
Ricardo
The price is S$157
includes taxes & fees
1 Dec - 2 Dec
ULIV Pulse Roma - Condesa
A multi-story building with balconies, a storefront, and parked cars.

9. Apartments Art Tanat

Apartments Art Tanat
2.0 star property
Roma Sur, 1.4 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (199 reviews)
"Perfect area , this was 2nd time staying there. Great place"
United States
Matthew
The price is S$105
includes taxes & fees
1 Dec - 2 Dec
Apartments Art Tanat
A hotel room with a balcony, a bed with white linens, and a view of the cityscape.

10. Casa Oliva

Casa Oliva
3.0 star property
Roma Norte, 1.7 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (190 reviews)
"I will definitely go back The staff the apartment so cozy and clean Safe all secured just can’t stop raving about it"
United States
Lisa
The price is S$176
includes taxes & fees
17 Nov - 18 Nov
Casa Oliva
A hotel room with a bed, a desk with a computer, a television, and a view of the outside.

11. Roma Nueve Dos Hotel Boutique

Roma Nueve Dos Hotel Boutique
4.0 star property
Roma Norte, 1.5 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (44 reviews)
"Great location, cute little boutique hotel, everything brand new. Nice rooftop bar as well as a separate martini bar on the second floor. Staff very friendly and helpful. Good choice of place to stay in central Roma district."
United States
Eric
The price is S$299
includes taxes & fees
16 Nov - 17 Nov
Roma Nueve Dos Hotel Boutique
A room with a view of a balcony, white chairs, and a table with a vase of flowers.

12. Roso Guest House

Roso Guest House
5.0 star property
Roma Norte, 1.3 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (116 reviews)
"Perfect location. Hotel was beautiful. Staff was so nice and helpful."
United States
Lyndsey
The price is S$331
includes taxes & fees
25 Nov - 26 Nov
Roso Guest House
A modern kitchen with a dining area, a large window, and a view of the outdoors.

13. Casa Mannach

Casa Mannach
3.5 star property
Hipódromo, 1.7 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (158 reviews)
"Truly couldn't have asked for a better spot to stay. Every person I spoke with was incredibly helpful and kind; from the cleaning staff to Luis and Pablo who always said hello whenever I would walk in and out. Would absolutely come back to stay again."
United States
Rebekah
The price is S$182
includes taxes & fees
16 Nov - 17 Nov
Casa Mannach
A modern living room with a sofa, dining table, and chairs, a kitchen area with a refrigerator, and large windows offering a view of greenery.

14. Boga Mexico City by Lumina

Boga Mexico City by Lumina
4.5 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (99 reviews)
"Clean room & air conditioning was such a plus!! The bed was so comfy!!!! I would definitely stay here again"
United States
Dianaris
The price is S$265
includes taxes & fees
8 Dec - 9 Dec
Boga Mexico City by Lumina
A modern kitchen with a refrigerator, wooden cabinets, and a dining area with a table and chairs.

15. Roma Norte Trendy Apartments by VIATO

Roma Norte Trendy Apartments by VIATO
3.0 star property
Roma Norte, 1.1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (12 reviews)
"The staff were very helpful and super kind . Love the area close by to all the restaurants that I love . And the apartment was super clean . Thank you!!"
United States
Sarah
The price is S$96
includes taxes & fees
7 Dec - 8 Dec
Roma Norte Trendy Apartments by VIATO
A modern bedroom with a large bed, a TV mounted on the wall, and a balcony with outdoor furniture.

16. OM686 Urban Lofts Short-Long Stays

OM686 Urban Lofts Short-Long Stays
3.0 star property
1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (278 reviews)
"Excellent location during my time there. Staff were very helpful and accommodating."
United States
Aloefuna
The price is S$79
includes taxes & fees
30 Nov - 1 Dec
OM686 Urban Lofts Short-Long Stays
A modern interior with a large window, wooden furniture, and potted plants.

17. Casa Tenue

Casa Tenue
3.5 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (22 reviews)
"The design of Casa Tenue is exceptionally thoughtful and beautiful. Each detail has been carefully conceived to create a visual and functional environment. Both Jorge and Joseph were very attentive hosts. All together a totally unique and wonderful experience."
United States
Donald
The price is S$805
includes taxes & fees
23 Nov - 24 Nov
Casa Tenue
A modern, well-lit room with a bed, a dining table, and a kitchen area.

18. ONTO Alvaro Obregon Mexico City

ONTO Alvaro Obregon Mexico City
4.0 star property
Roma Norte, 1.2 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (181 reviews)
"Great overall stay!"
United States
Federico
The price is S$275
includes taxes & fees
8 Dec - 9 Dec
ONTO Alvaro Obregon Mexico City
A modern building with a covered outdoor seating area surrounded by potted plants and trees.

19. Cuadra 134 Residencial Condesa

Cuadra 134 Residencial Condesa
4.5 star property
Roma Norte, 1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (438 reviews)
"It was very safe close to everything and they were very helpful the entire time."
United States
Mariela
The price is S$179
includes taxes & fees
12 Dec - 13 Dec
Cuadra 134 Residencial Condesa
A modern living room with a grey sofa, two black side tables, and a painting of a bridge.

20. Narvarte Living

Narvarte Living
3.0 star property
1.1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (20 reviews)
"Great space at a great rate. We would definitely stay here again."
United States
Daniel
The price is S$114
includes taxes & fees
9 Dec - 10 Dec
Narvarte Living
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to National Medical Center (Siglo XXI)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A building with ornate tiled facades, arched windows, and a balcony with a wrought iron railing.
Casa Talavera by Tasman
2.5 star property
10.0
Exceptional
10 reviews
View
A courtyard with a staircase leading to a second floor, surrounded by potted plants and a large hedge.
Casa Seis Siete
3.0 star property
10.0
Exceptional
67 reviews
View
A courtyard with outdoor seating, a stone wall, and a variety of plants.
Casa Bamboo
2.0 star property
9.8
Exceptional
18 reviews
View
A narrow alley with brick walls, potted plants, and a tree trunk.
Taá Guesthouse
4.0 star property
9.8
Exceptional
9 reviews
View
A rooftop pool with lounge chairs and potted plants, overlooking a cityscape.
Xoma Boutique Stays by Viadora
4.0 star property
9.8
Exceptional
260 reviews
View

Top National Medical Center (Siglo XXI) Hotel Reviews

A historic building with multiple balconies, a ground-floor shop, and a well-lit entrance.
Histórico Central Hotel

Histórico Central Hotel

Histórico Central Hotel
Historic Center

10/10 Excellent

Excellent location right smack in the city. Check in was smooth with an English-speaking staff at the front desk. In fact, all the staff was friendly and helpful. When we arrived, doorman saw our uber stop across the street and came over to get our luggage for us Room was a good size for 2 pax Breakfast was good The best part is the free flow of food which includes sandwiches, soups, snacks, etc and non-alcoholic drinks and hot drinks available from the hotel cafe.
Singapore
SIEN THENG
Reviewed June 24, 2026
Histórico Central Hotel

Frequently Asked Questions

What's the area like around National Medical Center (Siglo XXI)?

National Medical Center (Siglo XXI) is located in a historic area of Mexico City known for its top museums and popular art scene. If you're looking for a convenient place to stay, take a look at the 712 hotels and other accommodation options you'll find within a mile.

What's the best place to stay close to National Medical Center (Siglo XXI)?

Hotel Benidorm Mexico City is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free valet parking. It's located just a short 0.4 mi (0.7 km) from National Medical Center (Siglo XXI). Other good choices close by include ULIV Roma Norte and Hotel El Estadio.

How many hotels will I be able to find close to National Medical Center (Siglo XXI)?

Expedia has 712 hotels and other accommodation options within a mile from National Medical Center (Siglo XXI).

If I need to cancel the hotel reservation for my stay near National Medical Center (Siglo XXI), will I receive a refund?

Yes, most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best deals near National Medical Center (Siglo XXI).

What can I see and do near National Medical Center (Siglo XXI)?

Chapultepec Castle, Templo Mayor Museum and San Ildefonso College feature a variety of fascinating exhibits to see while you're in town. Palacio de Bellas Artes, Paseo de la Reforma and Cibeles Fountain are some of the local landmarks to explore. You can watch performances at Blackberry Auditorium, Poliforum Siqueiros and Teatro Metropólitan if you're interested in local theatre.

How can I get to National Medical Center (Siglo XXI)?

With so many choices for transport, seeing the area around National Medical Center (Siglo XXI) is a breeze. You can access metro transport at Revolution Station, Metrobús Revolución Station and Buenavista Metro Station. To see more of the larger area, ride aboard one of the trains from Mexico City Buenavista Station.