
Hotels near North Main Street Historic District
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Our top choices for North Main Street Historic District hotels

Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff4.1 km from North Main Street Historic District
9.4 out of 10, Exceptional, (809 reviews)
The price is S$134
includes taxes & fees
12 Apr - 13 Apr

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff5.3 km from North Main Street Historic District
9.4 out of 10, Exceptional, (879 reviews)
The price is S$159
includes taxes & fees
8 Apr - 9 Apr

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff3.5 km from North Main Street Historic District
9.2 out of 10, Wonderful, (1,004 reviews)
The price is S$136
includes taxes & fees
12 Apr - 13 Apr

Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHG4.4 km from North Main Street Historic District
8.8 out of 10, Excellent, (724 reviews)
The price is S$165
includes taxes & fees
2 Apr - 3 Apr

Comfort Inn Poplar Bluff North
Comfort Inn Poplar Bluff North3.7 km from North Main Street Historic District
7.8 out of 10, Good, (405 reviews)
The price is S$133
includes taxes & fees
15 Apr - 16 Apr

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO7.3 km from North Main Street Historic District
8.0 out of 10, Very good, (1,002 reviews)
The price is S$98
includes taxes & fees
29 Mar - 30 Mar

Super 8 by Wyndham Poplar Bluff Missouri
Super 8 by Wyndham Poplar Bluff Missouri4.4 km from North Main Street Historic District
6.6 out of 10, (637 reviews)
The price is S$80
includes taxes & fees
17 Apr - 18 Apr

Lake Wappapello
Lake Wappapello9.3 km from North Main Street Historic District
10.0 out of 10, Exceptional, (1 review)
The price is S$115
includes taxes & fees
1 Apr - 2 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to North Main Street Historic District
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Hampton Inn Poplar Bluff | 9.4 Exceptional 809 reviews | View | ||||||
![]() Fairfield Inn & Suites by Marriott Poplar Bluff | 9.4 Exceptional 879 reviews | View | ||||||
![]() Drury Inn & Suites Poplar Bluff | 9.2 Wonderful 1,004 reviews | View | ||||||
![]() Holiday Inn Poplar Bluff by IHG | 8.8 Excellent 724 reviews | View | ||||||
![]() Comfort Inn Poplar Bluff North | 7.8 Good 405 reviews | View |
Top North Main Street Historic District Hotel Reviews

Hampton Inn By Hilton Dexter
10/10 Excellent




































