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Our top choices for North Main Street Historic District hotels

1. Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff4.1 km from North Main Street Historic District
9.4 out of 10, Exceptional, (1,018 reviews)
The price is S$128
includes taxes & fees
6 Dec - 7 Dec

2. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff5.3 km from North Main Street Historic District
9.4 out of 10, Exceptional, (977 reviews)
The price is S$140
includes taxes & fees
15 Nov - 16 Nov

3. Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff3.5 km from North Main Street Historic District
9.4 out of 10, Exceptional, (1,001 reviews)
The price is S$130
includes taxes & fees
15 Nov - 16 Nov

4. Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHG4.4 km from North Main Street Historic District
8.8 out of 10, Excellent, (806 reviews)
The price is S$114
includes taxes & fees
11 Dec - 12 Dec

5. Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO7.3 km from North Main Street Historic District
8.0 out of 10, Very good, (1,002 reviews)
The price is S$102
includes taxes & fees
23 Nov - 24 Nov

6. Comfort Inn Poplar Bluff North
Comfort Inn Poplar Bluff North3.7 km from North Main Street Historic District
7.8 out of 10, Good, (445 reviews)
The price is S$103
includes taxes & fees
6 Dec - 7 Dec

7. Super 8 by Wyndham Poplar Bluff Missouri
Super 8 by Wyndham Poplar Bluff Missouri4.4 km from North Main Street Historic District
6.6 out of 10, (680 reviews)
The price is S$92
includes taxes & fees
15 Nov - 16 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to North Main Street Historic District
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Hampton Inn Poplar Bluff | 9.4 Exceptional 1,018 reviews | View | ||||||
![]() Fairfield Inn & Suites by Marriott Poplar Bluff | 9.4 Exceptional 977 reviews | View | ||||||
![]() Drury Inn & Suites Poplar Bluff | 9.4 Exceptional 1,001 reviews | View | ||||||
![]() Holiday Inn Poplar Bluff by IHG | 8.8 Excellent 806 reviews | View | ||||||
![]() Motel 6 Poplar Bluff, MO | 8.0 Very good 1,002 reviews | View |
Hotels recommended for families near North Main Street Historic District

9.4 out of 10, Exceptional, (1,001)
The price is S$130
includes taxes & fees
15 Nov - 16 Nov


































