O Brien Hotels from from S$55
- Plan, book, travel with confidence
- Better togetherSave up to S$134 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Go beyond your typical stay in O Brien
Family friendly
Cottage
Check prices for these dates
Our top choices for O Brien hotels
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Holiday Inn Express & Suites Alachua - Gainesville Area by IHGAlachua
9.4 out of 10, Exceptional, (1,007 reviews)
"Staff and hotel were wonderful!"
Sandra
The price is S$164
includes taxes & fees
9 Mar - 10 Mar
Tru by Hilton Lake City
Tru by Hilton Lake CityLake City
9.2 out of 10, Wonderful, (1,009 reviews)
"Clean and staff was very kind "
Rosemary
The price is S$160
includes taxes & fees
1 Mar - 2 Mar
Days Inn by Wyndham Lake City I-10
Days Inn by Wyndham Lake City I-10Lake City
7.0 out of 10, Good, (1,002 reviews)
"Was quite and clean, a little dated but it was a good place to sleep they are pet friendly "
William
The price is S$86
includes taxes & fees
23 Feb - 24 Feb
La Quinta Inn & Suite by Wyndham Lake City
La Quinta Inn & Suite by Wyndham Lake CityLake City
8.8 out of 10, Excellent, (1,083 reviews)
"Excellent place to stay."
Donovan
The price is S$149
includes taxes & fees
1 Mar - 2 Mar
Palms Garden Inn
Palms Garden InnLake City
7.4 out of 10, Good, (584 reviews)
"Clean and nice staff "
apollo
The price is S$91
includes taxes & fees
25 Feb - 26 Feb
Super 8 by Wyndham Lake City
Super 8 by Wyndham Lake CityLake City
7.2 out of 10, Good, (693 reviews)
"Clean room, friendly staff, fantastic food!"
John
The price is S$90
includes taxes & fees
23 Feb - 24 Feb
Hampton Inn & Suites Lake City
Hampton Inn & Suites Lake CityLake City
9.4 out of 10, Exceptional, (1,000 reviews)
"The room was very clean and comfortable. Excellent breakfast and staff was very friendly and helpful."
Kenneth
The price is S$197
includes taxes & fees
23 Feb - 24 Feb
Best Western Plus Lake City
Best Western Plus Lake CityLake City
9.0 out of 10, Wonderful, (1,042 reviews)
"Great place to stay"
Jack
The price is S$117
includes taxes & fees
8 Mar - 9 Mar
Comfort Suites Lake City
Comfort Suites Lake CityLake City
9.6 out of 10, Exceptional, (1,002 reviews)
"The staff is great"
Tana
The price is S$162
includes taxes & fees
1 Mar - 2 Mar
Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75Alachua
9.4 out of 10, Exceptional, (486 reviews)
"We visited family in the area and stayed here, hotel was clean, quiet, staff was great and room was so comfortable and spacious for our family of 5. Will definitely stay again!"
Libbi
The price is S$163
includes taxes & fees
8 Mar - 9 Mar
Motel 6 – Lake City, Fl – Medical Center
Motel 6 – Lake City, Fl – Medical CenterLake City
8.2 out of 10, Very good, (109 reviews)
"Dog friendly and price."
John
The price is S$86
includes taxes & fees
1 Mar - 2 Mar
Days Inn by Wyndham Lake City I-75
Days Inn by Wyndham Lake City I-75Lake City
7.6 out of 10, Good, (1,003 reviews)
"The room was clean and comfortable. The parking and surrounding area were good. Staff was friendly. "
Lars
The price is S$90
includes taxes & fees
23 Feb - 24 Feb
Quality Inn White Springs Suwanee
Quality Inn White Springs SuwaneeLive Oak
7.2 out of 10, Good, (640 reviews)
"Hotel is an older facility but room was clean and staff were exceptionally friendly and professional."
Wayne
The price is S$100
includes taxes & fees
8 Mar - 9 Mar
Americas Best Value Inn Lake City
Americas Best Value Inn Lake CityLake City
8.6 out of 10, Excellent, (1,006 reviews)
"Nice quiet and comfortable hotel a little gem."
Tim
The price is S$96
includes taxes & fees
23 Feb - 24 Feb
BlueGem Motel
BlueGem MotelHigh Springs
9.2 out of 10, Wonderful, (409 reviews)
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
Julians
The price is S$104
includes taxes & fees
23 Feb - 24 Feb
Home2 Suites by Hilton Lake City
Home2 Suites by Hilton Lake CityLake City
9.4 out of 10, Exceptional, (764 reviews)
"This is an excellent hotel while you roadtrip:)"
Desiree Moreno
The price is S$189
includes taxes & fees
1 Mar - 2 Mar
Quality Inn Lake City
Quality Inn Lake CityLake City
8.0 out of 10, Very good, (982 reviews)
"Staff were great and room was clean and comfortable "
Ethan
The price is S$121
includes taxes & fees
23 Mar - 24 Mar
Baymont by Wyndham Lake City I-75
Baymont by Wyndham Lake City I-75Lake City
5.0 out of 10, (1,004 reviews)
"Excelente"
Eduardo
The price is S$84
includes taxes & fees
23 Feb - 24 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about O Brien
Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.
Top O Brien Hotel Reviews
Recent Reviews in O Brien
Americas Best Value Inn Lake City
10/10 Excellent
More cheap stays in O Brien
Motel 6 – Lake City, Fl – Medical Center
3340 W US Highway 90 Lake City FL
The price is S$86 per night from 1 Mar to 2 Mar
S$86
1 Mar - 2 Mar
includes taxes & fees
8.2/10 Very Good! (109 reviews)
