Hotels near Odessa Regional Medical Center South Campus

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29 Dec - 30 Dec
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Odessa Regional Medical Center South Campus hotels

Free breakfast
Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG
2.5 star property
3 km from Odessa Regional Medical Center South Campus
8.8 out of 10, Excellent, (470)
"Room was nicely cleaned & staff was very polite. "
United States
Mariano
The price is S$148
includes taxes & fees
18 Jan - 19 Jan, 2026
Holiday Inn Express & Suites Odessa I-20 by IHG
Lobby
Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street
2.0 star property
1.3 km from Odessa Regional Medical Center South Campus
7.8 out of 10, Good, (501)
"Clean, quiet and a good price. The management here is quat"
United States
Ronald
The price is S$89
includes taxes & fees
31 Dec - 1 Jan, 2026
Motel 6 Odessa, TX - 2nd Street
Desk, laptop workspace, blackout curtains, iron/ironing board
MainStay Suites Odessa I-20

MainStay Suites Odessa I-20

MainStay Suites Odessa I-20
2.5 star property
2.9 km from Odessa Regional Medical Center South Campus
8.2 out of 10, Very good, (300)
"Very clean very spacious rooms friendly staff loved it"
United States
Jamayea
The price is S$125
includes taxes & fees
2 Jan - 3 Jan, 2026
MainStay Suites Odessa I-20
View from room
SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa
3.0 star property
2.6 km from Odessa Regional Medical Center South Campus
7.4 out of 10, Good, (78)
"Very nice place to stay "
United States
Jerry
The price is S$124
includes taxes & fees
31 Dec - 1 Jan, 2026
SureStay Plus Hotel by Best Western Odessa
Rollaway beds, free WiFi
Villa West Inn

Villa West Inn

Villa West Inn
2.0 star property
2.6 km from Odessa Regional Medical Center South Campus
7.4 out of 10, Good, (178)
"Clean room, clean toilet and good staffs."
United States
Francis
The price is S$89
includes taxes & fees
31 Dec - 1 Jan, 2026
Villa West Inn
Living area
DELUX INN

DELUX INN

DELUX INN
2.5 star property
2.5 km from Odessa Regional Medical Center South Campus
6.8 out of 10, (24)
"Best hotel "
United States
Poncho
The price is S$96
includes taxes & fees
7 Jan - 8 Jan, 2026
DELUX INN
Blackout curtains, free WiFi, bed sheets
Motel 6 Odessa, TX

Motel 6 Odessa, TX

Motel 6 Odessa, TX
2.0 star property
2.7 km from Odessa Regional Medical Center South Campus
6.8 out of 10, (553)
"The room was very clean. And management was very helpful."
United States
Bonnie
The price is S$95
includes taxes & fees
1 Jan - 2 Jan, 2026
Motel 6 Odessa, TX
Children’s area
Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG
3.0 star property
4 km from Odessa Regional Medical Center South Campus
8.8 out of 10, Excellent, (144)
"Excellent "
United States
Jeannette
The price is S$117
includes taxes & fees
31 Dec - 1 Jan, 2026
Staybridge Suites Odessa - Interstate HWY 20 by IHG
Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool loungers
Hawthorn Extended Stay by Wyndham Odessa

Hawthorn Extended Stay by Wyndham Odessa

Hawthorn Extended Stay by Wyndham Odessa
3.5 star property
4.1 km from Odessa Regional Medical Center South Campus
8.6 out of 10, Excellent, (269)
"Clean room, reasonable price and restaurant on site which was perfect after a long day of driving"
United States
Kimberly
The price is S$132
includes taxes & fees
9 Jan - 10 Jan, 2026
Hawthorn Extended Stay by Wyndham Odessa
Property amenity
Candlewood Suites Odessa by IHG

Candlewood Suites Odessa by IHG

Candlewood Suites Odessa by IHG
2.5 star property
3.9 km from Odessa Regional Medical Center South Campus
8.6 out of 10, Excellent, (190)
"It was a smaller place than i have stayed before, it does not have a pool, but still great place to stay."
United States
Alice
The price is S$124
includes taxes & fees
1 Jan - 2 Jan, 2026
Candlewood Suites Odessa by IHG
Lobby
TownePlace Suites by Marriott Odessa

TownePlace Suites by Marriott Odessa

TownePlace Suites by Marriott Odessa
3.0 star property
5.1 km from Odessa Regional Medical Center South Campus
9.0 out of 10, Wonderful, (513)
"Great service and breakfast was very good."
United States
Iris
The price is S$145
includes taxes & fees
3 Jan - 4 Jan, 2026
TownePlace Suites by Marriott Odessa
Desk, laptop workspace, blackout curtains, iron/ironing board
Sleep Inn & Suites Odessa near University

Sleep Inn & Suites Odessa near University

Sleep Inn & Suites Odessa near University
2.5 star property
4.6 km from Odessa Regional Medical Center South Campus
8.6 out of 10, Excellent, (466)
"Very good"
United States
Sharmin
The price is S$94
includes taxes & fees
23 Jan - 24 Jan, 2026
Sleep Inn & Suites Odessa near University
View from room
MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa
3.5 star property
5.5 km from Odessa Regional Medical Center South Campus
9.0 out of 10, Wonderful, (1003)
"incredible stay at a 5 star hotel in Odessa Texas. Room was clean; Staff was excellent; Food was delicious. was pleasantly surprised. will stay out there again while visiting family & friends!"
United States
Patricia
The price is S$148
includes taxes & fees
2 Jan - 3 Jan, 2026
MCM Elegante Hotel and Conference Center Odessa
Exterior
Fairfield Inn & Suites Odessa

Fairfield Inn & Suites Odessa

Fairfield Inn & Suites Odessa
2.5 star property
4.9 km from Odessa Regional Medical Center South Campus
8.8 out of 10, Excellent, (412)
"The rooms were clean and spacious. And the free breakfast was the best! I would totally stay here again. "
United States
Tina
The price is S$140
includes taxes & fees
4 Jan - 5 Jan, 2026
Fairfield Inn & Suites Odessa
Full-sized fridge, microwave
Parkway Inn

Parkway Inn

Parkway Inn
2.0 star property
4.4 km from Odessa Regional Medical Center South Campus
8.4 out of 10, Very good, (35)
"The cleanliness, tv and bed was awesome "
United States
Ellie
Parkway Inn
Full-sized fridge, microwave, stovetop, coffee/tea maker
Studio 6 Odessa, TX

Studio 6 Odessa, TX

Studio 6 Odessa, TX
2.5 star property
4 km from Odessa Regional Medical Center South Campus
8.0 out of 10, Very good, (242)
"This property puts several others. I’ve stayed in Odessa to shame. This is a nice property. The rooms are clean and spacious that I’ve been in. There was a door that didn’t open particularly easy in room 102 but that didn’t really interfere with my trip at all. I would stay at this facility again."
United States
JIMMY
The price is S$118
includes taxes & fees
9 Jan - 10 Jan, 2026
Studio 6 Odessa, TX
Lobby
Sonesta Essential Hotels Odessa

Sonesta Essential Hotels Odessa

Sonesta Essential Hotels Odessa
2.0 star property
3.7 km from Odessa Regional Medical Center South Campus
7.8 out of 10, Good, (752)
"Nice place"
United States
Jose
The price is S$99
includes taxes & fees
13 Jan - 14 Jan, 2026
Sonesta Essential Hotels Odessa
Outdoor pool
Hampton Inn by Hilton Odessa

Hampton Inn by Hilton Odessa

Hampton Inn by Hilton Odessa
2.5 star property
4.9 km from Odessa Regional Medical Center South Campus
8.6 out of 10, Excellent, (368)
"Always a great place to stay!!!"
United States
Xavier
The price is S$133
includes taxes & fees
4 Jan - 5 Jan, 2026
Hampton Inn by Hilton Odessa
Lobby
Comfort Inn & Suites, Odessa I-20

Comfort Inn & Suites, Odessa I-20

Comfort Inn & Suites, Odessa I-20
2.5 star property
4 km from Odessa Regional Medical Center South Campus
7.8 out of 10, Good, (571)
"Room was clean and comfortable "
United States
Dolores
The price is S$111
includes taxes & fees
18 Jan - 19 Jan, 2026
Comfort Inn & Suites, Odessa I-20
Restaurant
MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa
3.0 star property
5.9 km from Odessa Regional Medical Center South Campus
8.6 out of 10, Excellent, (1244)
"Thanks to God we had an amazing time "
United States
Ar'Letha
The price is S$104
includes taxes & fees
22 Jan - 23 Jan, 2026
MCM Grande Hotel FunDome Odessa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Odessa Regional Medical Center South Campus Hotel Reviews

MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa

10/10 Excellent
"Clean clean room loved it!!"
Chantel 1-night trip
Posted 4 days ago
MCM Elegante Hotel and Conference Center Odessa

Hotels near other Odessa Regional Medical Center South Campus attractions

White-Pool House

4.3/5 (20 reviews)
You can find out about the history of Odessa when you stop by White-Pool House. Experience the area's entertainment venues or attend a sporting event.
See properties

Parker House Museum

3.9/5 (53 reviews)
You can spend time studying the exhibits at Parker House Museum in Odessa. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Odessa Regional Medical Center South Campus?
Odessa Regional Medical Center South Campus is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Odessa Regional Medical Center South Campus?
Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.5 mi (0.7 km) from Odessa Regional Medical Center South Campus. Another good option is Motel 6 Odessa, TX - 2nd Street, located just 0.8 mi (1.3 km) away.
How many hotels will I be able to find close to Odessa Regional Medical Center South Campus?
Expedia has 9 hotels and other accommodation options within a mile from Odessa Regional Medical Center South Campus.
If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center South Campus, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Odessa Regional Medical Center South Campus.
What can I see and do near Odessa Regional Medical Center South Campus?
White-Pool House, Ellen Noel Art Museum and Parker House Museum feature a variety of fascinating exhibits to see while you're in town. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Globe of the Great Southwest and Presidential Museum and Leadership Library highlight the local culture.