Penrose Holidays
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Where to stay in Penrose
Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.
Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.
Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.
St. Charles Historic District
St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.
Creve Coeur
Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Top hotels in Penrose
Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch
"Exceptional location and you can literally walk outside to the archway. Super clean, nice staff, clean rooms. I was there for work where I could have gone to others for cheaper but not likely the view and location. Only downside was the garage system was not working all weekend, so self parking was ..."
Reviewed on 5 Oct, 2026
Drury Plaza Hotel St. Louis at the Arch
"The staff was very helpful and friendly especially the breakfast staff, Lavern would greet each person with a smile. She is so sweet. It is a beautiful historic hotel."
Reviewed on 4 Oct, 2026
Stay near popular Penrose attractions
Julia Davis Branch Library
Things to do
StL's Signature "Sights and Bites" - Private Tour in St. Louis
Downtown St. Louis Smartphone Guided Audio Walking Tour App
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.