Default HTG hotel image

Hotels near Poplar Bluff Regional Medical Center

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Poplar Bluff Regional Medical Center hotels

A Hampton Inn hotel with a brick facade, multiple windows, and a well-lit entrance.

1. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
1.3 km from Poplar Bluff Regional Medical Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Everything was great about the stay!"
United States
Denise
The price is S$129
includes taxes & fees
6 Dec - 7 Dec
Hampton Inn Poplar Bluff
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

2. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
0.2 km from Poplar Bluff Regional Medical Center
9.4 out of 10, Exceptional, (978 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
United States
ELAINE
The price is S$135
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites by Marriott Poplar Bluff
An indoor swimming pool with a clear view of the outside through large windows.

3. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
1.8 km from Poplar Bluff Regional Medical Center
9.4 out of 10, Exceptional, (1,002 reviews)
"I like how clean they were, and the food was excellent and the hot tub was great"
United States
Alan
The price is S$137
includes taxes & fees
22 Nov - 23 Nov
Drury Inn & Suites Poplar Bluff
A Holiday Inn hotel with a covered entrance, multiple floors, and a parking lot.

4. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
1 km from Poplar Bluff Regional Medical Center
8.8 out of 10, Excellent, (807 reviews)
"Always an enjoyable stay"
United States
Nathan
The price is S$109
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Poplar Bluff by IHG
A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.

5. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
2.1 km from Poplar Bluff Regional Medical Center
8.0 out of 10, Very good, (1,001 reviews)
"Rooms were large and clean. Bathroom was large with a nice shower. Parking was convenient Would definitely stay again."
United States
Jim
The price is S$93
includes taxes & fees
27 Nov - 28 Nov
Motel 6 Poplar Bluff, MO
A hotel with a covered entrance, multiple windows, and a yellow facade.

6. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
1.6 km from Poplar Bluff Regional Medical Center
7.8 out of 10, Good, (445 reviews)
"Rooms are quiet and check in was very easy. Breakfast was not the best and very dated decor."
United States
Lin
The price is S$104
includes taxes & fees
6 Dec - 7 Dec
Comfort Inn Poplar Bluff North
A hotel room with a desk, chair, television, and a bed.

7. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
1.1 km from Poplar Bluff Regional Medical Center
6.6 out of 10, (681 reviews)
"I stay here quite often when I come into town, most the time room is clean and fresh, this time the room had a urine smell, the bed needed repair or replaced, there was an issue with expedia and I got charged twice but expedia did refund the money. Overall disappointed with this stay and will start staying at the drury from now on."
United States
Michael
The price is S$87
includes taxes & fees
20 Nov - 21 Nov
Super 8 by Wyndham Poplar Bluff Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Poplar Bluff Regional Medical Center

A Hampton Inn hotel with a brick facade, multiple windows, and a well-lit entrance.

Hampton Inn Poplar Bluff

2.5 star property
1.3 km from Poplar Bluff Regional Medical Center
View
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

Fairfield Inn & Suites by Marriott Poplar Bluff

3.0 star property
0.2 km from Poplar Bluff Regional Medical Center
View
An indoor swimming pool with a clear view of the outside through large windows.

Drury Inn & Suites Poplar Bluff

3.0 star property
1.8 km from Poplar Bluff Regional Medical Center
View
A Holiday Inn hotel with a covered entrance, multiple floors, and a parking lot.

Holiday Inn Poplar Bluff by IHG

3.0 star property
1 km from Poplar Bluff Regional Medical Center
View
A modern hotel lobby with a reception desk, seating area, and a view of the outdoors.

Motel 6 Poplar Bluff, MO

2.0 star property
2.1 km from Poplar Bluff Regional Medical Center
View
9.4
Exceptional
1,000 reviews
9.4
Exceptional
978 reviews
9.4
Exceptional
1,002 reviews
8.8
Excellent
807 reviews
8.0
Very good
1,001 reviews
The price is S$129
includes taxes & fees
6 Dec - 7 Dec
The price is S$135
includes taxes & fees
22 Nov - 23 Nov
The price is S$137
includes taxes & fees
22 Nov - 23 Nov
The price is S$109
includes taxes & fees
13 Dec - 14 Dec
The price is S$93
includes taxes & fees
27 Nov - 28 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Top Poplar Bluff Regional Medical Center Hotel Reviews

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"Breakfast very good!"
doug 1-night trip
Posted 1 day ago
Hampton Inn Poplar Bluff
Lake Wappapello

Lake Wappapello

10/10 Excellent
"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."
Dottie 1-night trip
Posted 2 months ago
Lake Wappapello

Frequently asked questions

What's the area like around Poplar Bluff Regional Medical Center?
Poplar Bluff Regional Medical Center is located in Poplar Bluff. Travellers like this family-friendly area for its restaurants. You'll find 19 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay near Poplar Bluff Regional Medical Center?
Adjacent to Poplar Bluff Regional Medical Center, Fairfield Inn & Suites by Marriott Poplar Bluff is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices within a short distance include Holiday Inn Poplar Bluff by IHG and Hampton Inn Poplar Bluff.
How many hotels will I be able to find close to Poplar Bluff Regional Medical Center?
Expedia has 19 hotels and other accommodation options a few miles from Poplar Bluff Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Poplar Bluff Regional Medical Center, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best deals available near Poplar Bluff Regional Medical Center.
What can I see and do near Poplar Bluff Regional Medical Center?
You'll want to browse the exhibits at Mo-Ark Regional Railroad Museum and Margaret Harwell Art Museum. You might plan a visit to Black River Coliseum or Ozark Ridge Golf Course while you're in the area. Poplar Bluff History Museum and North Main Street Historic District are both worth a visit while you're out exploring.