What's it like in Puerto Santa Ana?

Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.

Where is the best hotel for a stay in Puerto Santa Ana?

Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE .

How many hotels should I expect to find in Puerto Santa Ana?

If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 63 Puerto Santa Ana hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?

Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.

What is there to do around this Guayaquil neighbourhood?

Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.

Top 10 Puerto Santa Ana Hotels of 2025

Top 10 Hotels in Puerto Santa Ana

"Great hotel."

20 Jun - 21 Jun

43-inch flat-screen TV with digital channels, TV, Netflix

"Beautiful view"

25 Jun - 26 Jun

"Todo exelente "

16 Jun - 17 Jun

"The owner came to meet us and showed us the apartment. He is fluent in English and he was available to answer our calls promptly. The apartment was beautifully furnished and clean. We were missing a large pot for cooking soup. He arranged for his wife to bring it to the apartment. We would definitely return there for our next visit."

"I love that the property is clean, and you can walk to the Mall of the Sol, which is safe and offers a nice spa, pool, and Jacuzzi. "

5 Jul - 6 Jul

"Excellent location, friendly staff"

20 Jun - 21 Jun

"Near the airport and staff was great"

22 Jun - 23 Jun

"I love this hotel"

14 Jul - 15 Jul

"The staff are fabulous! "

22 Jun - 23 Jun

"Close to the airport, clean room, great staff."

22 Jun - 23 Jun

Outdoor pool, open 8:00 AM to 9:00 PM, pool loungers

"The hotel was nice and clean very organized, the food was delicious about the employees all of them are kind and friendly specially Giannella and Stairon I would like to say thank you very much for your hospitality. I highly recommend the hotel we had a great experience thank you 🤗"

28 Jun - 29 Jun

"Comfy fair price we like the mall attached to it ,very convenient…great breakfast "

20 Jun - 21 Jun

"A great location in Guayaquil! The staff were so helpful, easy access from airport. Great facilities overall. "

28 Jun - 29 Jun

"This hotel is a good value for your money..."

27 Jun - 28 Jun

"I loved everything from the hotel. Mainly very comfortable and clean beds. The prompt attention of the employees to any guests requests. Walkable distance to main attractions. You’re looking for a nice and clean hotel book it with Patrimonial by Greenfield. : ) "

"Nice staff, clean room, good food "

28 Jun - 29 Jun

"Great place, great people. Excellent service and hotel. "

"The best thing about the hotel are the staff members and location."

1 bedroom, desk, laptop workspace, blackout curtains

"Love all the beautiful stone they used to build the hotel!"

16 Jun - 17 Jun

"Great alternative to expensive US chain hotels near GYE. Very clean and the breakfast at the adjoining restaurant is delicious. I will be back for sure! "

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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

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Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

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Kennedy

1 out of top 10 points of interest in this area

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

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Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

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