A densely packed urban area with numerous buildings and a prominent tower on a hill.

Hotels in Puerto Santa Ana

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Check prices for these dates

This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

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Our top choices for Puerto Santa Ana hotels

A modern bar area with a bar counter, seating, and a large window.

1. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana
9.2 out of 10, Wonderful, (1,018 reviews)
"This is my top place everytime I go to Guayaquil,"
United States
maria
The price is S$164
20 Sept - 21 Sept
Wyndham Guayaquil Puerto Santa Ana
A rooftop terrace with outdoor seating, a pool, and a city view at sunset.

2. River View suites Puerto Santa Ana gye

River View suites Puerto Santa Ana gye
3.0 star property
Puerto Santa Ana
9.0 out of 10, Wonderful, (62 reviews)
"Nice place to stay!"
United States
Aaliyah
The price is S$125
5 Sept - 6 Sept
River View suites Puerto Santa Ana gye
A rooftop pool with a view of the city skyline.

3. Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana
9.4 out of 10, Exceptional, (109 reviews)
"So clean and very nice people. I really recommend this facility, nice environment. My next trip lm booking in this apartment"
United States
Pedro
The price is S$110
30 Aug - 31 Aug
Luxury Suites Riverfront GYE
A grand room with ornate chandeliers, a large sofa, a round armchair, and a fireplace.

4. Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 0.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (143 reviews)
"Great place historical. Good service n breakfast. Great location"
United States
Mary Grant
The price is S$84
7 Sept - 8 Sept
Mansión del Río
An outdoor seating area with tables and chairs, potted plants, and a view of trees through large windows.

5. Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (333 reviews)
"Great location."
United States
George S
The price is S$86
4 Sept - 5 Sept
Ibis Styles El Malecon Guayaquil
A breakfast table with various foods and a view of a park through a window.

6. Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels
4.0 star property
Rocafuerte, 2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"Great Ecuadorian breakfast, super clean room."
United States
Jason
The price is S$98
25 Sept - 26 Sept
Unipark by Oro Verde Hotels
A cocktail on a marble table with a pool in the background.

7. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 1.4 km from Puerto Santa Ana
8.4 out of 10, Very good, (162 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is S$58
26 Aug - 27 Aug
Hotel Patrimonial by Greenfield
A hotel lobby with a modern design, featuring a reception desk, seating area, and decorative columns.

8. Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 1.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (950 reviews)
"There’s a restaurant downstairs. Try the Encocado de camarón. Best food ever!"
United States
Marlaynna
The price is S$93
25 Sept - 26 Sept
Hotel Palace Guayaquil
A modern lobby with large windows, a staircase, and comfortable seating areas.

9. Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 1.7 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (123 reviews)
"Good staff...great location"
United States
ALBERTO
The price is S$120
6 Sept - 7 Sept
Doubletree By Hilton Guayaquil
An aerial view of a hotel with a swimming pool surrounded by lush greenery and a decorative garden.

10. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 2.2 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,004 reviews)
"I enjoyed everything about this hotel."
United States
Maria Dorila
The price is S$103
25 Sept - 26 Sept
Grand Hotel Guayaquil, Centro Histórico.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

11. Hotel Ramada

Hotel Ramada
3.0 star property
Downtown Guayaquil, 1.3 km from Puerto Santa Ana
8.0 out of 10, Very good, (410 reviews)
"Love the area where the hotel is located. Excellent breakfast. The pool area is beautiful where you can seat and relax "
United States
Sixto
The price is S$81
26 Aug - 27 Aug
Hotel Ramada
An outdoor cafe with tables and chairs, surrounded by trees and buildings.

12. Fortune Hotel

Fortune Hotel
3.0 star property
River City, 1 km from Puerto Santa Ana
7.6 out of 10, Good, (9 reviews)
"Is a great place the only problem is the disco bars outside the hotel "
United States
MARIA
The price is S$49
23 Sept - 24 Sept
Fortune Hotel
A gym with various exercise equipment, including a stationary bike, an elliptical trainer, and a treadmill. There is a potted plant and a mirror on the wall.

13. Hotel Cityzen Guayaquil

Hotel Cityzen Guayaquil
3.0 star property
Roca, 1.6 km from Puerto Santa Ana
8.8 out of 10, Excellent, (42 reviews)
"Great central location in Centro (Downtown) Guayaquil. The staff were very helpful and always there when I needed them."
United States
Tahmidul
The price is S$64
29 Aug - 30 Aug
Hotel Cityzen Guayaquil
A modern hotel lobby with a reception desk, seating area, and a large decorative plant.

14. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.5 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (1,010 reviews)
"Good staff, excelent food. I will defenetly will come back"
United States
Gloria E
The price is S$114
4 Sept - 5 Sept
Courtyard by Marriott Guayaquil
An outdoor patio with wicker furniture, a stone wall, and a water feature.

15. Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 2.7 km from Puerto Santa Ana
8.4 out of 10, Very good, (254 reviews)
"👍"
United States
Marcos
The price is S$84
27 Aug - 28 Aug
Hotel Marcelius
A person in a swimsuit and red hat sitting on a green inflatable ring in a pool.

16. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 2.1 km from Puerto Santa Ana
9.6 out of 10, Exceptional, (1,011 reviews)
"Very nice stay"
United States
Freddy
The price is S$119
6 Sept - 7 Sept
Oro Verde Guayaquil
A modern interior with a seating area, a kitchen, and a dining space.

17. Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
3.7 km from Puerto Santa Ana
9.4 out of 10, Exceptional, (1,011 reviews)
"Fantastic service and accommodations"
United States
Charles
The price is S$139
25 Sept - 26 Sept
Holiday Inn Guayaquil Airport by IHG
A modern bar area with a bar counter, stools, and a seating area with a table and chairs.

18. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 2.8 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (1,011 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is S$106
20 Sept - 21 Sept
Wyndham Garden Guayaquil
A spacious indoor area with a central open space surrounded by seating arrangements and a pool.

19. Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 2.9 km from Puerto Santa Ana
9.2 out of 10, Wonderful, (727 reviews)
"The room was clean, the staff is great, and the food is good too. The food is very expensive, and there is a bad smell coming from the bathroom at night; it seems like something is wrong with the sewer"
United States
Maria
The price is S$115
29 Aug - 30 Aug
Radisson Hotel Guayaquil
A buffet setup with pastries and various food items in jars.

20. Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 2.9 km from Puerto Santa Ana
9.0 out of 10, Wonderful, (681 reviews)
"It has been a great experience staying at the Sheraton. The staff is friendly, professional, and welcoming. The rooms are clean, spacious, and comfortable. Overall, it is definitely a great place to stay, and I would highly recommend it to anyone visiting Guayaquil."
United States
James T
The price is S$138
18 Sept - 19 Sept
Sheraton Guayaquil Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travellers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A green and yellow iguana on a rocky surface.

Urdesa

Urdesa is well liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

A golden statue of two figures forming a heart shape on a paved area with a modern building in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Simón Bolívar

When in Simón Bolívar, you can plan a visit to Mall del Sol Shopping Center and San Marino Mall, some noteworthy sights in the nearby area.

Top Puerto Santa Ana Hotel Reviews

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

10/10 Excellent
"Great hotel to stay in! Staff was super friendly!"
Isabel 3-night trip
Posted 1 hour ago
Wyndham Guayaquil Puerto Santa Ana

Frequently asked questions

What's it like in Puerto Santa Ana?
Puerto Santa Ana is a welcoming neighbourhood that travellers like for its restaurants and sporting events.
Where is the best hotel for a stay in Puerto Santa Ana?
Based on our traveller data, Wyndham Guayaquil Puerto Santa Ana is one of the top choices for your stay in Puerto Santa Ana. This hotel offers a full-service spa and 2 restaurants. Another good choice for your stay in the area is Luxury Suites Riverfront GYE.
How many hotels should I expect to find in Puerto Santa Ana?
If you're searching for places to stay in Guayaquil, Expedia has something to meet your needs with 90 Puerto Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Puerto Santa Ana, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Puerto Santa Ana.
What is there to do around this Guayaquil neighbourhood?
Emporium by The Point, Santa Ana Garden and Botanical Garden are just a few of the places to visit in and around Puerto Santa Ana. While you're out sightseeing, Santa Ana Hill and Numa Pompilio Llona Street are a couple of additional sights to visit in Guayaquil.

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