𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Puxico (2026)

A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

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Our top choices for Puxico hotels

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

1. Hampton Inn By Hilton Dexter

Dexter

Bryan

S$142

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a reception desk, seating area, and large windows.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

2. Drury Inn & Suites Poplar Bluff

Poplar Bluff

Dean

S$136

includes taxes & fees

29 Oct - 30 Oct

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

3. Hampton Inn Poplar Bluff

Poplar Bluff

Rhonda

S$130

includes taxes & fees

1 Nov - 2 Nov

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A corner market with a refrigerated display case and a pantry area.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

4. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Nancy

S$140

includes taxes & fees

18 Oct - 19 Oct

A diner with booth seating, a checkered floor, and a counter with a cash register.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

5. Travelodge by Wyndham Dexter

Dexter

Steven

S$125

includes taxes & fees

1 Nov - 2 Nov

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

6. Dexter Inn

Dexter

Edward

S$100

includes taxes & fees

13 Oct - 14 Oct

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

A hotel with a brick facade, multiple windows, and a covered entrance area.

7. Econo Lodge Dexter

Dexter

Herman

S$74

includes taxes & fees

10 Nov - 11 Nov

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

8. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

Nathan

S$122

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

A motel with a prominent '66' sign, large windows, and a flat roof.

9. Motel 6 Poplar Bluff, MO

Poplar Bluff

Cindy

S$102

includes taxes & fees

26 Oct - 27 Oct

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel lobby with a coffee station, seating area, and a television screen.

A hotel with a covered entrance, multiple windows, and a yellow facade.

10. Comfort Inn Poplar Bluff North

Poplar Bluff

Muhammad

S$107

includes taxes & fees

8 Nov - 9 Nov

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

A bathroom with a bathtub, toilet, and a shower curtain.

A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.

11. OYO Hickory House Inn

Dexter

DIEGO

S$87

includes taxes & fees

26 Oct - 27 Oct

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A two-story motel with a covered parking area and a bench outside.

12. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

Diana

S$97

includes taxes & fees

26 Oct - 27 Oct

A living room with a blue wall, a fireplace, a sofa, and a chair.

A bar area with stools and a counter where a bartender is serving drinks.

A brick building with a sign reading "Mercantile & Hotel".

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

13. EC Reed's Mercantile and Hotel

Marble Hill

Miranda

S$147

includes taxes & fees

13 Oct - 14 Oct

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A calm lake with a wooden dock and a forested island in the distance.

A bedroom with a wooden bed, a bench, and a window.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

14. Lake Wappapello

Williamsville

Tonya

S$122

includes taxes & fees

13 Oct - 14 Oct

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

A room with wooden paneling, a ceiling fan, a dining table with chairs, and a sofa.

A spacious dining area with a stone wall, wooden furniture, and a fireplace.

A house with a red door, a porch with rocking chairs, and a wreath on the door.

15. 40-acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

Anonymous traveller

S$380

includes taxes & fees

21 Oct - 22 Oct

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Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

10/10 Excellent

"Hotel has been recently remodeled. Room was very clean. Staff was so helpful especially Sue who checked us in!"

Holiday Inn Poplar Bluff by IHG

8/10 Good

"Beds were ok. Could be updated, little hard but slept ok. AC was loins in our particular room. Told front desk n said they would be sure to have it looked at. The suite was incredible large."

Motel 6 Poplar Bluff, MO

8/10 Good

"I only stayed here from midnight until 5:30. It was clean, however the bed was very thin and uncomfortable and the heat/ac didn't work correctly which happens sometimes. The thermostat said 75 and it was freezing. It was a good place to crash for a few hours."

EC Reed's Mercantile and Hotel

10/10 Excellent

"On street parking, quiet little town, absolutely beautiful little hotel, diner, and general store. Very unique! It’s a whole experience staying here. I would love an opportunity to stop here again if I’m ever going through this area again."

Hampton Inn By Hilton Dexter

10/10 Excellent

"This place is Brand new and really great!"

Lake Wappapello

10/10 Excellent

"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO

S$97

26 Oct - 27 Oct

includes taxes & fees

Dexter Inn

1807 W Business US Highway 60 Dexter MO

S$100

13 Oct - 14 Oct

includes taxes & fees

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

S$102

26 Oct - 27 Oct

includes taxes & fees

8/10 Very good! (1,002 reviews)

Comfort Inn Poplar Bluff North

2582 N Westwood Blvd Poplar Bluff MO

S$107

8 Nov - 9 Nov

includes taxes & fees

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO

S$130

1 Nov - 2 Nov

includes taxes & fees

9.4/10 Exceptional! (979 reviews)

Hampton Inn By Hilton Dexter

2179 Gill Plaza Drive Dexter MO

S$142

18 Oct - 19 Oct

includes taxes & fees

9.6/10 Exceptional! (78 reviews)

Frequently asked questions

What's the best place for a stay in Puxico?

Holiday Inn Poplar Bluff by IHG, located 18.8 mi (30.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Hampton Inn Poplar Bluff and Motel 6 Poplar Bluff, MO. See all available top hotels, or vacation rentals in Puxico.

If I need to cancel my hotel reservation in Puxico, will I receive a refund?

Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.

What is staying in Puxico like?

Travellers to Puxico will find plenty to explore and enjoy. There are 52 hotels and other accommodation options in the surrounding area. Find out more about Puxico.

What is there to see in Puxico?

A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.

What's the seasonal weather in Puxico?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

Puxico Hotels from S$74

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Puxico

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Puxico hotels

1. Hampton Inn By Hilton Dexter

2. Drury Inn & Suites Poplar Bluff

3. Hampton Inn Poplar Bluff

4. Fairfield Inn & Suites by Marriott Poplar Bluff

5. Travelodge by Wyndham Dexter

6. Dexter Inn

7. Econo Lodge Dexter

8. Holiday Inn Poplar Bluff by IHG

9. Motel 6 Poplar Bluff, MO

10. Comfort Inn Poplar Bluff North

11. OYO Hickory House Inn

12. Super 8 by Wyndham Poplar Bluff Missouri

13. EC Reed's Mercantile and Hotel

14. Lake Wappapello

15. 40-acre Poplar Bluff Nature Lovers Paradise!

Learn more about Puxico

Top Puxico Hotel Reviews

Hampton Inn Poplar Bluff

Holiday Inn Poplar Bluff by IHG

Motel 6 Poplar Bluff, MO

EC Reed's Mercantile and Hotel

Hampton Inn By Hilton Dexter

Lake Wappapello

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

Dexter Inn

Motel 6 Poplar Bluff, MO

Comfort Inn Poplar Bluff North

Hampton Inn Poplar Bluff

Hampton Inn By Hilton Dexter

Frequently asked questions

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