Hotels near Saint Francis Medical Center

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
16 Mar - 17 Mar
Tomorrow
17 Mar - 18 Mar
This weekend
20 Mar - 22 Mar
Next weekend
27 Mar - 29 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Saint Francis Medical Center hotels

Lobby

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
0.5 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (795 reviews)
"Great place to stay. Clean and close to restaurants! "
United States
Diane
The price is S$153
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Cape Girardeau I 55 East
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
0.8 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (1,006 reviews)
"My favorite place tpstay when in the area."
United States
Jack
The price is S$145
includes taxes & fees
22 Mar - 23 Mar
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
0.5 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Clean room staff is very nice parking it great "
United States
Arriel
The price is S$143
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Free daily buffet breakfast

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
0.9 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (1,001 reviews)
"The room was great and the staff was friendly as always. "
United States
LuAnne
The price is S$130
includes taxes & fees
22 Mar - 23 Mar
Drury Inn & Suites Cape Girardeau
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
1.5 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (166 reviews)
"Nearby Mexican restaurant, clean room, pleasant staff, good breakfast choices "
United States
Larry
The price is S$146
includes taxes & fees
22 Mar - 23 Mar
Fairfield Inn & Suites by Marriott Cape Girardeau
Desk, laptop workspace, blackout curtains, free cots/infant beds

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
0.9 km from Saint Francis Medical Center
9.0 out of 10, Wonderful, (1,003 reviews)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is S$104
includes taxes & fees
22 Mar - 23 Mar
Pear Tree Inn Cape Girardeau West
Exterior

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
1.6 km from Saint Francis Medical Center
8.2 out of 10, Very good, (904 reviews)
"Nice room and easy access to bathroom "
United States
Maureen
The price is S$110
includes taxes & fees
18 Mar - 19 Mar
Candlewood Suites Cape Girardeau by IHG
Desk, free WiFi

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
2 km from Saint Francis Medical Center
6.0 out of 10, (212 reviews)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is S$94
includes taxes & fees
7 Apr - 8 Apr
Town House Inn Cape Giradreau
Lobby

Rockwood Inn

Rockwood Inn
2.0 star property
3.6 km from Saint Francis Medical Center
10.0 out of 10, Exceptional, (20 reviews)
"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
The price is S$199
includes taxes & fees
31 Mar - 1 Apr
Rockwood Inn
Lobby

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
4.3 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (496 reviews)
"Very nice hotel!"
United States
Angie
The price is S$182
includes taxes & fees
29 Mar - 30 Mar
Courtyard by Marriott Cape Girardeau Downtown
Snack bar

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
5.7 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (116 reviews)
"It was a nice stay"
United States
Douglas
The price is S$131
includes taxes & fees
1 Apr - 2 Apr
Tru By Hilton Cape Girardeau
Lobby sitting area

The Riverview

The Riverview
4.0 star property
4.9 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (528 reviews)
"Room was perfect"
United States
Derrick
The price is S$118
includes taxes & fees
18 Mar - 19 Mar
The Riverview
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
6.7 km from Saint Francis Medical Center
9.0 out of 10, Wonderful, (724 reviews)
"Enjoy our stay "
United States
Reginald
The price is S$124
includes taxes & fees
18 Mar - 19 Mar
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
6.7 km from Saint Francis Medical Center
8.2 out of 10, Very good, (751 reviews)
"Beds felt amazing. My family and I had a great time"
United States
Gary
The price is S$127
includes taxes & fees
31 Mar - 1 Apr
Comfort Suites Jackson-Cape Girardeau
Lobby

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
15.3 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (1,005 reviews)
"The staff is so nice here"
United States
Laura
The price is S$109
includes taxes & fees
22 Mar - 23 Mar
Drury Inn & Suites Jackson MO
Lobby

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
3.8 km from Saint Francis Medical Center
7.2 out of 10, Good, (710 reviews)
"Room was clean. Staff was friendly. Hotel itself is due for a renovation. You get what you pay for. 2.5 out of 5 for this place "
United States
Robin
The price is S$96
includes taxes & fees
31 Mar - 1 Apr
Quality Inn Cape Girardeau North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Saint Francis Medical Center Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Clean, excellent hospitality, great food and service "
Laura 1-night trip
Posted 4 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

Hotels near other Saint Francis Medical Center attractions

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park

Riverfront Bridge Park

4.4/5 (74 reviews)
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Saint Francis Medical Center?
Saint Francis Medical Center is located in Cape Girardeau. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 8 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Saint Francis Medical Center?
Drury Plaza Hotel Cape Girardeau Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Saint Francis Medical Center. Other good choices within a short distance include Drury Inn & Suites Cape Girardeau and Candlewood Suites Cape Girardeau by IHG.
How many hotels are there close to Saint Francis Medical Center?
Expedia has 8 hotels and other accommodation options within a mile from Saint Francis Medical Center.
If I need to cancel the hotel reservation for my stay near Saint Francis Medical Center, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best options available near Saint Francis Medical Center.
What can I see and do near Saint Francis Medical Center?
You might spend a leisurely day outdoors at Cape Rock Park and Fort D Historic Site. Create some family memories at Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. You might plan a visit to Show Me Center or eDen Spa & Salon while you're in the area.