San Francisco

Panama City

A bridge over a body of water with several boats.
A beach with a large driftwood piece, calm water, and a few people in the distance.
A city skyline with a flag, a river, and a park.
A cityscape with a distinctive twisted skyscraper, a busy highway, and surrounding modern buildings.
A cityscape with a rainbow over buildings.

Stay near popular San Francisco attractions

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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Things to do

Panama Canal: The Most Complete Monkey Island Experience

Panama Canal: The Most Complete Wildlife Experience

S$77
per adult
94% of travellers recommend
Panama Canal: The Most Complete Wildlife Experience
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

S$54
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Half day of Panama city and canal tour: shared and private

Half day of Panama city and canal tour: shared and private

S$86
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
Panama Canal Half Transit Experience

Panama Canal Partial Transit

S$193
per adult
86% of travellers recommend
Panama Canal Partial Transit
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

S$128
per adult
94% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
San Blas Island-Hopping : Full-Day Adventure from Panama City

San Blas Island-Hopping : Full-Day Adventure from Panama City

S$174
per adult
San Blas Island-Hopping : Full-Day Adventure from Panama City
See all activities in Panama City

Top hotels in San Francisco

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is S$274 per night from 3 Sept to 4 Sept
S$274
3 Sept - 4 Sept
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
Megapolis Hotel Panamá
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
The price is S$175 per night from 6 Sept to 7 Sept
S$175
6 Sept - 7 Sept
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and a nightclub. Our guests praise the helpful staff in their reviews. Popular ...
Aloft by Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is S$165 per night from 6 Sept to 7 Sept
S$165
6 Sept - 7 Sept
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ...
9/10 Wonderful! (1,009 reviews)
"Everything was nice"

Reviewed on 28 Aug, 2026

Courtyard by Marriott Panama Multiplaza Mall
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
The price is S$157 per night from 27 Sept to 28 Sept
S$157
27 Sept - 28 Sept
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
8.6/10 Excellent! (1,719 reviews)
"staff was all but helpful"

Reviewed on 27 Aug, 2026

Decapolis Hotel Panama City
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is S$232 per night from 29 Aug to 30 Aug
S$232
29 Aug - 30 Aug
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ...
Las Americas Golden Tower Panama
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
The price is S$154 per night from 6 Sept to 7 Sept
S$154
6 Sept - 7 Sept
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,329 reviews)
"👌"

Reviewed on 27 Aug, 2026

Ramada Plaza by Wyndham Panama Punta Pacifica
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.
Photo by My World
Open Photo by My World

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

San Francisco