Santa Cruz Holidays

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Top hotels in Santa Cruz

Camino Real Hotel

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo Santa Cruz
The price is S$190 per night from 20 Apr to 21 Apr
S$190
20 Apr - 21 Apr
9/10 Wonderful! (423 reviews)
Good property the great amenities and service

Reviewed on 24 Mar, 2026

Camino Real Hotel
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is S$70 per night from 5 Apr to 6 Apr
S$70
5 Apr - 6 Apr
9.6/10 Exceptional! (99 reviews)
Good

Reviewed on 8 Mar, 2026

Ibis Santa Cruz DE LA Sierra
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
The price is S$191 per night from 20 Apr to 21 Apr
S$191
20 Apr - 21 Apr
9/10 Wonderful! (365 reviews)
Yes

Reviewed on 8 Mar, 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
See all 290 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Guarani Nandereko Nomai Art and Culture Center

Enjoy an outing to Guarani Nandereko Nomai Art and Culture Center during your stay in Santa Cruz. While in the area, you can find time to visit its shops.

Guarani Nandereko Nomai Art and Culture Center

What to do in Santa Cruz

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

S$109
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
Trekking through the area of ​​​​the last armed struggle of Che Guevara.

3D/2N Getaway on the Che Guevara Route Live the Adventure!

S$896
per adult
3D/2N Getaway on the Che Guevara Route Live the Adventure!
The Che Guevara route is the most peculiar tourist destination in Bolivia.

4D/3N Expedition: Che Guevara Route - Disconnect from the World

S$1,027
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
See all activities in Santa Cruz

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.