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Hotels in Santo Domingo

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Our top choices for Santo Domingo hotels

Hotel Amomoxtli

Hotel Amomoxtli
4.0 star property
Santo Domingo
9.4 out of 10, Exceptional, (644)
"The resort was gorgeous, the staff were lovely and the food was delicious!"
United States
Anna
Hotel Amomoxtli

Hotel Zaragoza Tepoztlan

Hotel Zaragoza Tepoztlan
3.0 star property
Santo Domingo
8.8 out of 10, Excellent, (126)
"Excellent service and place."
United States
Rodrigo
The price is S$197
includes taxes & fees
30 Dec - 31 Dec
Hotel Zaragoza Tepoztlan

Posada Vista Tepoz

Posada Vista Tepoz
2.5 star property
Santo Domingo
7.8 out of 10, Good, (50)
"Todo excelente "
Mexico
JESUS
The price is S$108
includes taxes & fees
30 Dec - 31 Dec
Posada Vista Tepoz

AVICENA HOTEL BOUTIQUE

AVICENA HOTEL BOUTIQUE
3.0 star property
16.8 km from Santo Domingo
9.8 out of 10, Exceptional, (9)
"Muy lindo el hotel, y muy buena atención."
Mexico
Alexander
The price is S$203
includes taxes & fees
11 Jan - 12 Jan, 2026
AVICENA HOTEL BOUTIQUE

Hotel Eterna Primavera Cuernavaca

Hotel Eterna Primavera Cuernavaca
3.0 star property
16.8 km from Santo Domingo
8.2 out of 10, Very good, (21)
"Geeat place"
Canada
Brett Douglas
The price is S$51
includes taxes & fees
30 Dec - 31 Dec
Hotel Eterna Primavera Cuernavaca

Xhiara Hotel

Xhiara Hotel
3.0 star property
27.1 km from Santo Domingo
9.4 out of 10, Exceptional, (8)
"the room and everywhere was very clean an quiet place. The staff very helpful and friendly. Breakfast was good. The only thing that wasn't good was the Wifi very slow poor signal but other than that everything else was great "
United States
Palmira
The price is S$196
includes taxes & fees
5 Jan - 6 Jan, 2026
Xhiara Hotel

POSADA ALI By OREALTY

POSADA ALI By OREALTY
3.0 star property
0.9 km from Santo Domingo
8.0 out of 10, Very good, (2)
"No incluye el desayuno y te cobran el vaso de agua a 31 pesos,eso no debe ser asi"
Mexico
Alexa Ximena
The price is S$167
includes taxes & fees
30 Dec - 31 Dec
POSADA ALI By OREALTY

Hotel Integra Tepoztlán

Hotel Integra Tepoztlán
3.0 star property
0.4 km from Santo Domingo
8.0 out of 10, Very good, (3)
"Es cómoda, bien ubicada! Buen precio"
Mexico
Ángela Teresita de Jesús
The price is S$111
includes taxes & fees
31 Dec - 1 Jan, 2026
Hotel Integra Tepoztlán

Hotel de Cuautla

Hotel de Cuautla
3.0 star property
23.8 km from Santo Domingo
8.4 out of 10, Very good, (281)
"Good location, very attentive staff and with private parking."
United States
Victor Hugo
The price is S$88
includes taxes & fees
7 Jan - 8 Jan, 2026
Hotel de Cuautla

Posada del Tepozteco - Hotel & Gallery

Posada del Tepozteco - Hotel & Gallery
4.0 star property
San Miguel, 1.1 km from Santo Domingo
9.2 out of 10, Wonderful, (394)
"Beautiful Property, the rooms were awesome "
United States
Martha
The price is S$318
includes taxes & fees
30 Dec - 31 Dec
Posada del Tepozteco - Hotel & Gallery

Hosteria Las Quintas Hotel

Hosteria Las Quintas Hotel
4.0 star property
15.2 km from Santo Domingo
9.2 out of 10, Wonderful, (1006)
"Great place to stay "
United States
Jorge
The price is S$146
includes taxes & fees
4 Jan - 5 Jan, 2026
Hosteria Las Quintas Hotel

One Cuernavaca

One Cuernavaca
3.0 star property
12.9 km from Santo Domingo
8.8 out of 10, Excellent, (1001)
"Excelente "
Mexico
Mariano
The price is S$115
includes taxes & fees
4 Jan - 5 Jan, 2026
One Cuernavaca

Hotel Boutique Casa Fernanda - Adults only

Hotel Boutique Casa Fernanda - Adults only
4.0 star property
0.7 km from Santo Domingo
9.2 out of 10, Wonderful, (291)
"Most amazing stay!"
United States
Delanie
Hotel Boutique Casa Fernanda - Adults only

Hotel Quinta de La Rosa Cuautla

Hotel Quinta de La Rosa Cuautla
3.0 star property
25.1 km from Santo Domingo
7.0 out of 10, Good, (118)
"Room not like in pictures hair in the sink and bath they took about 30 minutes to open the door because I get late nite I don't feel the price I pay for the service I got please do something about it"
United States
Ubaldo
The price is S$85
includes taxes & fees
30 Dec - 31 Dec
Hotel Quinta de La Rosa Cuautla

Colibrí Hotel

Colibrí Hotel
3.0 star property
San Miguel, 1.3 km from Santo Domingo
9.0 out of 10, Wonderful, (185)
"Very nice family-owned hotel. Personalized service walking distance to main town center"
United States
Gilberto
Colibrí Hotel

Rustika Spa Hotel Boutique

Rustika Spa Hotel Boutique
3.5 star property
1 km from Santo Domingo
9.4 out of 10, Exceptional, (110)
"Amazing place!!"
United States
Carlos
The price is S$245
includes taxes & fees
2 Jan - 3 Jan, 2026
Rustika Spa Hotel Boutique

Casa Ehua Hotel Galería

Casa Ehua Hotel Galería
3.0 star property
1.3 km from Santo Domingo
8.8 out of 10, Excellent, (84)
"Small but cute !! "
United States
Raffaele
Casa Ehua Hotel Galería

La Buena Vibra Wellness Resort & SPA

La Buena Vibra Wellness Resort & SPA
4.5 star property
Valle de Atongo, 1.6 km from Santo Domingo
8.8 out of 10, Excellent, (211)
"Excellent place to rest and beautiful view"
United States
Gabriela
La Buena Vibra Wellness Resort & SPA

Hotel y Restaurante El Ciruelo

Hotel y Restaurante El Ciruelo
4.0 star property
0.8 km from Santo Domingo
9.0 out of 10, Wonderful, (283)
"Location is great, staff is helpful and friendly, food is very tasty. "
United States
Jose
The price is S$230
includes taxes & fees
5 Jan - 6 Jan, 2026
Hotel y Restaurante El Ciruelo

Holiday Inn Express Hotel & Suites Cuernavaca by IHG

Holiday Inn Express Hotel & Suites Cuernavaca by IHG
3.0 star property
17.6 km from Santo Domingo
9.0 out of 10, Wonderful, (1002)
"Clean room , good breakfast, spacious room, coffee bag every day, need to take Uber or taxis to get around . Good hotel "
United States
Raffaele
The price is S$113
includes taxes & fees
26 Jan - 27 Jan, 2026
Holiday Inn Express Hotel & Suites Cuernavaca by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Domingo

Find the best Santo Domingo areas for the activities you enjoy most.

San Miguel

If you're spending some time in San Miguel, Artisan Market of Tepoztlán and Ex-Convent of the Nativity are top sights worth seeing.

Valle de Atongo

Though Valle de Atongo may not have many top sights, you can venture to the surrounding area to see attractions like Los Venaditos Waterfall and Jardín Xolatlaco.

Santa Cecilia

While Santa Cecilia may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Artisan Market of Tepoztlán and El Suspiro Tepoztlan.

La Presa

While there might not be top attractions in La Presa, you can explore the larger area and discover places like Los Venaditos Waterfall and Artisan Market of Tepoztlán.

San Pedro

While there might not be top attractions in San Pedro, you can explore the larger area and discover places like El Suspiro Tepoztlan and Artisan Market of Tepoztlán.

Top Santo Domingo Hotel Reviews

Frequently asked questions

What is Santo Domingo like?
Travellers to the Santo Domingo neighbourhood in Tepoztlán will be sure to enjoy their stay. Are you looking for Santo Domingo travel tips? Make sure that you visit New Tepoztlán Market and Tepoztlán Museum Carlos Pellicer Collection while you're in the neighbourhood.
What's the best accommodation in Santo Domingo?
Based on Expedia customer reviews, Hotel Amomoxtli is the highest ranked property in Santo Domingo. This hotel offers a full-service spa and a restaurant. Other favourite options in the area include Hotel Zaragoza Tepoztlan and Posada Vista Tepoz.
How many hotels are there in Santo Domingo?
Expedia has 27 hotels and other accommodation options in Santo Domingo to choose from, making this an ideal home base for exploring the greater Tepoztlán area.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Santo Domingo.
What is there to do in this Tepoztlán neighbourhood?
A few attractions you might want to check out while you're in Santo Domingo are New Tepoztlán Market and Tepoztlán Museum Carlos Pellicer Collection. While you're out sightseeing in Tepoztlán, make sure that you visit other sights such as Ex-Convent of the Nativity or Artisan Market of Tepoztlán.