Hotels near Science Center of Iowa

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
15 Dec - 16 Dec
Tomorrow
16 Dec - 17 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Science Center of Iowa hotels

Lobby sitting area
Des Lux Hotel

Des Lux Hotel

Des Lux Hotel
3.5 star property
Court District, 0.7 km from Science Center of Iowa
9.8 out of 10, Exceptional, (1034)
"Beautiful and clean hotel with very friendly staff."
United States
Scott
The price is S$215
includes taxes & fees
16 Dec - 17 Dec
Des Lux Hotel
Dinner served
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton
4.5 star property
Western Gateway, 0.8 km from Science Center of Iowa
9.6 out of 10, Exceptional, (1066)
"Comfy and stylish lobby and rooms, delicious cafe"
United States
Sarah
The price is S$206
includes taxes & fees
4 Jan - 5 Jan, 2026
Hotel Fort Des Moines, Curio Collection by Hilton
Restaurant
Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection
4.0 star property
Court District, 0.5 km from Science Center of Iowa
9.4 out of 10, Exceptional, (1000)
"Great hotel"
United States
Grant
The price is S$208
includes taxes & fees
28 Dec - 29 Dec
Surety Hotel, Autograph Collection
Exterior
Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Historic East Village, 0.8 km from Science Center of Iowa
9.4 out of 10, Exceptional, (1003)
"The check in lady was a grouchy old bag."
United States
David
The price is S$124
includes taxes & fees
29 Dec - 30 Dec
Staybridge Suites Des Moines Downtown by IHG
Indoor pool, pool loungers
Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines, 0.8 km from Science Center of Iowa
9.2 out of 10, Wonderful, (969)
"Wonderful stay as always!"
United States
Brenda
The price is S$140
includes taxes & fees
18 Dec - 19 Dec
Holiday Inn Express & Suites Des Moines Downtown by IHG
Games room
Kasa Downtown Des Moines

Kasa Downtown Des Moines

Kasa Downtown Des Moines
4.0 star property
Downtown Des Moines, 0.8 km from Science Center of Iowa
9.2 out of 10, Wonderful, (111)
"Our stay in downtown Des Moines was for an entire week. This Kasa rental worked very well for us. It was nice having the extra things like kitchen, laundry, living room, game room, etc. that you don't get staying in a hotel. Our room was located in a noisy spot. We heard the garage doors open and close often. We were also awakened by the garage pickup. Still, it was a good value and great location for us."
United States
Marie
The price is S$222
includes taxes & fees
21 Dec - 22 Dec
Kasa Downtown Des Moines
Lobby sitting area
Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown
2.5 star property
Court District, 0.2 km from Science Center of Iowa
8.6 out of 10, Excellent, (1003)
"Nice hotel and conveniently located"
United States
shane
The price is S$126
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Des Moines Downtown
Exterior
AC Hotel Des Moines East Village

AC Hotel Des Moines East Village

AC Hotel Des Moines East Village
3.0 star property
Historic East Village, 1 km from Science Center of Iowa
9.2 out of 10, Wonderful, (405)
"Hotel was clean and staff friendly."
United States
Cathy
The price is S$218
includes taxes & fees
25 Dec - 26 Dec
AC Hotel Des Moines East Village
Property amenity
Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown
3.0 star property
Court District, 0.2 km from Science Center of Iowa
8.6 out of 10, Excellent, (563)
"Clean and spacious rooms with convenient walkable access to nearby restaurants and attractions. "
United States
Brooks
The price is S$139
includes taxes & fees
22 Dec - 23 Dec
Residence Inn Des Moines Downtown
Terrace/patio
Hilton Des Moines Downtown

Hilton Des Moines Downtown

Hilton Des Moines Downtown
3.5 star property
Downtown Des Moines, 0.9 km from Science Center of Iowa
9.0 out of 10, Wonderful, (1003)
"Great place "
United States
Eddie
The price is S$199
includes taxes & fees
21 Dec - 22 Dec
Hilton Des Moines Downtown
2 restaurants, breakfast, dinner served; American cuisine
Des Moines Marriott Downtown

Des Moines Marriott Downtown

Des Moines Marriott Downtown
3.5 star property
Downtown Des Moines, 0.7 km from Science Center of Iowa
8.8 out of 10, Excellent, (957)
"Great location, clean, easy check in and check out. "
United States
Emily
The price is S$195
includes taxes & fees
4 Jan - 5 Jan, 2026
Des Moines Marriott Downtown
BBQ/picnic Area
Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown
4.0 star property
Downtown Des Moines, 1.2 km from Science Center of Iowa
9.0 out of 10, Wonderful, (393)
"Clean room, quiet, excellent breakfast. "
United States
Randy
The price is S$136
includes taxes & fees
22 Dec - 23 Dec
Fairfield Inn & Suites by Marriott Des Moines Downtown
View from property
Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel
3.5 star property
Downtown Des Moines, 0.6 km from Science Center of Iowa
8.6 out of 10, Excellent, (1001)
"Great place to stay downtown. "
United States
Wesley
The price is S$195
includes taxes & fees
4 Jan - 5 Jan, 2026
Renaissance Des Moines Savery Hotel
Lobby
Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center
2.5 star property
Downtown Des Moines, 1.2 km from Science Center of Iowa
8.8 out of 10, Excellent, (1012)
"Breakfast was good"
United States
Cynthia
The price is S$122
includes taxes & fees
19 Dec - 20 Dec
Comfort Inn & Suites Event Center
Exterior
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown
3.5 star property
Historic East Village, 0.7 km from Science Center of Iowa
8.2 out of 10, Very good, (1058)
"Great breakfast "
United States
Dustin
The price is S$172
includes taxes & fees
22 Dec - 23 Dec
Embassy Suites Hotel Des Moines Downtown
Exterior
Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown
3.0 star property
Downtown Des Moines, 0.7 km from Science Center of Iowa
8.2 out of 10, Very good, (1001)
"Excellent location, very clean, good breakfast & the staff was great!"
United States
Dawn
The price is S$146
includes taxes & fees
1 Jan - 2 Jan, 2026
Hyatt Place Des Moines/Downtown
Exterior
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG
3.0 star property
Downtown Des Moines, 1.6 km from Science Center of Iowa
8.0 out of 10, Very good, (1000)
"Convenient location. Friendly, helpful staff."
United States
Deb
The price is S$147
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Downtown - Mercy Area by IHG
Iron/ironing board, free WiFi
Cozy Rest Motel

Cozy Rest Motel

Cozy Rest Motel
2.0 star property
Indianola Hills, 2.7 km from Science Center of Iowa
7.8 out of 10, Good, (651)
"This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out."
United States
Chuck
The price is S$103
includes taxes & fees
17 Dec - 18 Dec
Cozy Rest Motel
Terrace/patio
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake, 3.3 km from Science Center of Iowa
9.4 out of 10, Exceptional, (1005)
"Great place to stay and the employees were super nice and helpful"
United States
Amy
The price is S$132
includes taxes & fees
11 Jan - 12 Jan, 2026
Home2 Suites by Hilton Des Moines at Drake University
Reception
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Watrous South, 5.3 km from Science Center of Iowa
8.8 out of 10, Excellent, (1004)
"The best hotel Mattress I have EVER HAD."
United States
Cynthia
The price is S$149
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Science Center of Iowa Hotel Reviews

Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG

10/10 Excellent
"Yes it was and yes they wore great."
Cristofer 1-night trip
Posted 19 hours ago
Holiday Inn Express & Suites Des Moines Downtown by IHG

Hotels near other Science Center of Iowa attractions

Principal Park

4.5/5 (64 reviews)
Catch an event at Principal Park during your trip to Des Moines. Experience the area's great live music and lively festivals.
See properties

Des Moines' Downtown Farmers' Market

You can search for that perfect souvenir at Des Moines' Downtown Farmers' Market during your stay in Des Moines. Experience the area's great live music and acclaimed theatre scene.
See properties

Frequently asked questions

What's the area like around Science Center of Iowa?
Science Center of Iowa is located in an area of Des Moines known for its lively festivals. If you're looking for a convenient place to stay, take a look at the 165 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Science Center of Iowa?
Adjacent to Science Center of Iowa, Residence Inn Des Moines Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good options close by include Hotel Fort Des Moines, Curio Collection by Hilton and Des Lux Hotel.
How many hotels can I expect to find near Science Center of Iowa?
Expedia has 165 hotels and other accommodation options within a mile from Science Center of Iowa.
If I need to cancel the hotel reservation for my stay near Science Center of Iowa, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then filter by "fully refundable" to view top deals close to Science Center of Iowa.
What can I see and do near Science Center of Iowa?
State Historical Museum of Iowa, Des Moines Art Center and World Food Prize Hall of Laureates feature a variety of fascinating exhibits to see while you're in town. Salisbury House, Valley Junction and Walnut Street Bridge are some of the notable landmarks to see in the area. You can check out the local talent at Wooly's, Hoyt Sherman Place and Lauridsen Amphitheater.

Explore a world of travel with Expedia