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Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with fitness centre and 24-hour front desk

Choose dates to view prices

Just off I-55, Comfort Inn & Suites Sikeston I-55 provides a practical base for travelers. Guests can swim in the indoor pool, use the laundry facilities, connect with in-room WiFi, maintain fitness routines at the gym, or handle work matters in the business center.

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pet-friendly
  • Gym
  • Laundry
  • Parking included
  • Free WiFi
The current price is S$125
includes taxes & fees
7 Dec - 8 Dec

Room options

Available filters for rooms
Showing 5 of 5 rooms

View all photos for Standard Room, 2 Queen Beds, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)

Highlights

Air conditioning
Fridge
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Suite, 1 King Bed with Sofa bed, Non Smoking

Highlights

Air conditioning
Fridge
Sofa bed
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Accessible, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Room, 1 King Bed, Accessible, Non Smoking

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Air conditioning
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)

Highlights

Air conditioning
Fridge
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

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About the area

Map
109 Matthews Ln, Sikeston, MO, 63801

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.4 km
  • Central Park - 5 min drive - 5.5 km
  • Sikeston Depot Museum - 6 min drive - 5.5 km
  • Southeast Missouri State University - 41 min drive - 60.5 km
  • Isle Casino Cape Girardeau - 42 min drive - 61.2 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Cafe - ‬17 min walk
  • ‪Buffalo Wild Wings - ‬5 min drive
  • ‪Pizza Inn - ‬2 min drive
  • ‪Burger King - ‬4 min drive
  • ‪McDonald's - ‬2 min walk

About this property

Comfort Inn & Suites Sikeston I-55

Property highlights
Take advantage of laundry facilities, a gym and a business centre at Comfort Inn & Suites Sikeston I-55. Stay connected with free in-room WiFi.
Other perks include:
  • An indoor pool
  • Free self-parking
  • A 24-hour front desk, a front desk safe and laundry services
  • A lift
  • Guest reviews speak highly of the helpful staff
Room features
All 64 rooms offer comforts such as air conditioning, in addition to amenities such as free WiFi.
Extra amenities include:
  • Bathrooms with baths or showers
  • Cable channels, coffee/tea makers and desks

Similar properties

Property amenity

Drury Inn & Suites Sikeston, MO

  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
9.4 out of 10, Exceptional, 1,002 reviews
The price is S$141
includes taxes & fees
4 Dec - 5 Dec
Drury Inn & Suites Sikeston, MO

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business centre

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; check-in end time: anytime
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 20 per pet, per night
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 9 kg per pet)
Specific rooms only; pet-friendly rooms can be requested by contacting the property on the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Optional extras

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

Does Comfort Inn & Suites Sikeston I-55 have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of 6 Nov, 2025, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on 7 Dec, 2025 start from S$125.42, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Comfort Inn & Suites Sikeston I-55 pet-friendly?

Yes, Comfort Inn & Suites Sikeston I-55 allows cats and dogs (limit 2 total) with a maximum weight of up to 9 kg per pet. There's a fee of USD 20 per pet, per night. Service animals are exempt from fees.

How much is parking at Comfort Inn & Suites Sikeston I-55?

Self-parking is free at this property.

What time is check-in at Comfort Inn & Suites Sikeston I-55?

Check-in start time: 2:00 PM; check-in end time: anytime.

What time is check-out at Comfort Inn & Suites Sikeston I-55?

Checkout is at 11:00 AM.

Where is Comfort Inn & Suites Sikeston I-55 located?

Situated in Sikeston, this hotel is 0.4 mi (0.6 km) from City of Miner Convention Center and within 6 miles (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9 mi (14.5 km) away.

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Reviews

Comfort Inn & Suites Sikeston I-55 Reviews

8.4

Very good

8.4

Cleanliness

8.6

Location

8.8

Staff & service

8.2

Eco-friendliness

8.2

Property conditions & facilities
Rating 10 - Excellent. 128 out of 274 reviews
Rating 8 - Good. 91 out of 274 reviews
Rating 6 - Okay. 28 out of 274 reviews
Rating 4 - Poor. 18 out of 274 reviews
Rating 2 - Terrible. 9 out of 274 reviews

Reviews

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was a very nice stay. The pool was clean and enjoying!
Stayed 1 night in Jul 2025

10/10 Excellent

Peggy

Liked: Cleanliness, staff & service, property conditions & facilities
The facility was very nice.
Stayed 2 nights in May 2025

10/10 Excellent

Sasha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were happy with our stay
Stayed 1 night in Oct 2024

6/10 Okay

Wendy

Liked: Cleanliness, staff & service, property conditions & facilities
Everything was good. The beds were too hard and pillows were too soft.
Stayed 1 night in Jun 2025

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Thank you

Great stay, quiet, friendly and just what we expected!
Stayed 1 night in Feb 2025

10/10 Excellent

John

Liked: Cleanliness, staff & service, property conditions & facilities
Great for overnights, staff friendly and attentive
Stayed 1 night in Apr 2024

10/10 Excellent

Richard

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice place
Stayed 1 night in Nov 2023

10/10 Excellent

Amanda

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good place to lay your head at night

The staff was very friendly and checkin was quick. The rooms were well kept and the pool area was nicely kept. Would stay there again!
Stayed 1 night in Jul 2022

10/10 Excellent

Susan

Liked: Cleanliness, staff & service, property conditions & facilities
Check in was quick and easy. Very courteous and professional staff.
Stayed 1 night in Mar 2024

10/10 Excellent

Michael

Liked: Cleanliness, staff & service
we had a nice stay. no complaints.
Stayed 1 night in Jun 2023

10/10 Excellent

Gail

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
our room was clean and well kept.
Stayed 1 night in May 2024

6/10 Okay

Steven

Liked: Cleanliness, staff & service, amenities
Ok for moderately priced place
Stayed 1 night in Aug 2022

10/10 Excellent

Kim

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great service
Stayed 2 nights in Mar 2024

10/10 Excellent

Tina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was very easy to get to and easy on the highway. Clean. Check in was awesome. I would definitely stay here again.
Stayed 1 night in Sep 2023

10/10 Excellent

Mary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff were friendly and professional. They made check in and checkout seamless! Thank you!!
Stayed 1 night in Feb 2023

10/10 Excellent

Nate

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a nice location off of i55. Lots of fast food. Overall clean. No issues.
Stayed 1 night in Aug 2024

10/10 Excellent

charles

Liked: Staff & service, amenities, property conditions & facilities
Nice

8/10 Good

Lisa

Liked: Cleanliness, staff & service, property conditions & facilities
The only comment I have is that I had to go and ask for sheets and blanket for the sofa sleeper in our room it would have been nice to have them already available in the room. Other than that it was a restful stay.
Stayed 1 night in May 2023

10/10 Excellent

Dixie, Goshen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was clean & no “funky” smells.
Stayed 1 night in Sep 2022

2/10 Terrible

Michelle

Disliked: Cleanliness, amenities, property conditions & facilities
This property is very old the rooms are not clean at all for the price I would not stay here gain.
Stayed 1 night in Feb 2024

8/10 Good

Katherine

Liked: Cleanliness, staff & service, property conditions & facilities
This place was very nice. I couldn’t give it 5 stars as the check in desk gave our room to another guest along with the key. Boy was I surprised when a stranger opened my door! It got straightened out but then our key no longer worked. Was a hassle running to the front desk so much
Stayed 1 night in Oct 2024

6/10 Okay

Bryan

Liked: Staff & service
Disliked: Cleanliness, room comfort

Not bad if you’re only staying one night

We found wrappers on the floor. The bedding was washed in some cheap detergent that had us itching all night. The air conditioner is old and took all night to cool off the room. The beds feel like they put a mattress pad on top of a brick. Thankfull we only stayed one night.
Stayed 1 night in Jul 2024

8/10 Good

Kevin

Liked: Cleanliness, property conditions & facilities, room comfort

TV

We were not impressed with the TV quality. There was a delay in the voices and the person talking.
Stayed 1 night in Mar 2023

2/10 Terrible

kevin

Liked: Staff & service, amenities
Disliked: Cleanliness, property conditions & facilities
The room was nasty, ig looked like someone was still sleeping in it. I was transferred to another room and the toilet didn't work. Finally i git a decent room and staff made up for it by letting us swim about an hour past closing. Needless to say, ill never stay at that hotel again. Two words- overpriced and filthy!!!
Stayed 1 night in Jul 2022

4/10 Poor

Sherri

Disliked: Cleanliness
The check in process was easy and quick. We entered our room and I went to the restroom and the 1st thing I saw was a roach crawling on the wall. I was disgusted. I told my daughter not to unpack anything nor take out the food we had just purchased. I went over by the air conditioning unit and saw a 2nd roach. I removed our belongings and immediately went to the front desk. I told John the employee on duty and asked if this was common at this hotel he informed me that they have pest control and recently had them out. Needless to say I was issued another room. I was very leery and uncomfortable in the room. I took our bags back to the car and only kept out what we needed for the 2 days.
Stayed 2 nights in Sep 2023