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Southern Illinois Hotels from from S$73
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Our top choices for Southern Illinois hotels

Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1,002 reviews)
The price is S$146
includes taxes & fees
28 Feb - 1 Mar

Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,000 reviews)
The price is S$150
includes taxes & fees
13 Mar - 14 Mar

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,656 reviews)
The price is S$161
includes taxes & fees
15 Mar - 16 Mar

La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,007 reviews)
The price is S$137
includes taxes & fees
1 Mar - 2 Mar

Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (715 reviews)
The price is S$193
includes taxes & fees
28 Feb - 1 Mar

Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.0 out of 10, Wonderful, (663 reviews)
The price is S$129
includes taxes & fees
28 Feb - 1 Mar

Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. LouisEdwardsville
8.6 out of 10, Excellent, (669 reviews)
The price is S$143
includes taxes & fees
28 Feb - 1 Mar

Best Western U. S. Inn
Best Western U. S. InnNashville
8.6 out of 10, Excellent, (402 reviews)
The price is S$121
includes taxes & fees
9 Mar - 10 Mar

The Principal Hotel
The Principal HotelColumbia
9.8 out of 10, Exceptional, (206 reviews)
The price is S$153
includes taxes & fees
8 Mar - 9 Mar

Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,005 reviews)
The price is S$154
includes taxes & fees
8 Mar - 9 Mar

Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,001 reviews)
The price is S$147
includes taxes & fees
8 Mar - 9 Mar

Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,002 reviews)
The price is S$125
includes taxes & fees
22 Mar - 23 Mar

Home2 Suites By Hilton Effingham
Home2 Suites By Hilton EffinghamEffingham
9.8 out of 10, Exceptional, (38 reviews)
The price is S$194
includes taxes & fees
28 Feb - 1 Mar

SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
8.8 out of 10, Excellent, (933 reviews)
The price is S$101
includes taxes & fees
4 Mar - 5 Mar

Laketree Inn And Suites Marion
Laketree Inn And Suites MarionMarion
8.0 out of 10, Very good, (180 reviews)
The price is S$95
includes taxes & fees
22 Mar - 23 Mar

Holiday Inn Carbondale-Conference Center by IHG
Holiday Inn Carbondale-Conference Center by IHGCarbondale
8.8 out of 10, Excellent, (657 reviews)
The price is S$161
includes taxes & fees
1 Mar - 2 Mar

Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
9.0 out of 10, Wonderful, (1,000 reviews)
The price is S$147
includes taxes & fees
12 Mar - 13 Mar

Best Western Delta Inn
Best Western Delta InnEffingham
9.2 out of 10, Wonderful, (1,000 reviews)
The price is S$118
includes taxes & fees
8 Mar - 9 Mar

Clarion Pointe Mattoon near University
Clarion Pointe Mattoon near UniversityMattoon
8.4 out of 10, Very good, (878 reviews)
The price is S$128
includes taxes & fees
7 Mar - 8 Mar

Holiday Inn Express Metropolis by IHG
Holiday Inn Express Metropolis by IHGMetropolis
8.6 out of 10, Excellent, (1,000 reviews)
The price is S$134
includes taxes & fees
1 Mar - 2 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southern Illinois
Cottage

Pet-friendly Home w/ Fenced Yard: 'cozy in Casey'
Pet-friendly Home w/ Fenced Yard: 'cozy in Casey'Casey
10.0 out of 10, Exceptional, (1 review)
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Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
The price is S$73 per night from 4 Mar to 5 Mar
S$73
4 Mar - 5 Mar
includes taxes & fees
7/10 Good! (1,000 reviews)
Hotels in Southern Illinois with star rating

4 Star Hotels
4 properties
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