Find Luxury Hotels in St. Charles

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check availability on St. Charles Luxury Hotels

Top Luxury Hotels in St. Charles

Ameristar Casino Resort and Spa
Casino

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1009)
"What a fabulous hotel!!!! Will stay here again next time we're in the area!! "
The price is S$291
includes taxes & fees
19 Oct - 20 Oct
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District
Free daily buffet breakfast

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1014)
"Quality place to stay"
The price is S$170
includes taxes & fees
21 Oct - 22 Oct
Country Inn & Suites by Radisson, St. Charles Historic District
Relax Inn Saint Charles
Lobby

Relax Inn Saint Charles

2.0 star property
6.6 out of 10, (1008)
"Good stay"
The price is S$91
includes taxes & fees
13 Oct - 14 Oct
Relax Inn Saint Charles
Baymont by Wyndham St. Charles
Lobby

Baymont by Wyndham St. Charles

2.5 star property
8.0 out of 10, Very good, (1000)
"Friendly staff, great breakfast and clean"
Baymont by Wyndham St. Charles
Embassy Suites by Hilton St. Louis St. Charles
Lobby

Embassy Suites by Hilton St. Louis St. Charles

3.5 star property
8.8 out of 10, Excellent, (1065)
"Nice room, great amenities "
The price is S$207
includes taxes & fees
2 Nov - 3 Nov
Embassy Suites by Hilton St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St. Charles Hotel Reviews

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

10/10 Excellent
"It was close to the enterprise center"
Thomas 1-night trip
Posted 3 days ago
Drury Inn & Suites St. Louis Union Station

Explore a world of travel with Expedia

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.