Midtown
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Downtown St. Louis Smartphone Guided Audio Walking Tour App
St. Louis Premium Small Group Tour With Arch & River Cruise
St Louis Self-Guided Driving and Walking Audio Tour
St. Louis Premium Driving Tour with Boat Ride & Arch
Gateway Arch National Park Self Guided Audio Walking Tour
Top hotels in Midtown
Element St. Louis Midtown
The pool was too cold, but the hotel was clean and spacious!
Reviewed on 11 Mar, 2026
Residence Inn by Marriott St Louis Downtown
Pulled out the sofa bed and stains all over. Third person (that I paid for was not able to sleep on the mattress). Took pictures showed to front desk and they took the pictures from my phone and said “ok” . Absolutely disgusting.
Reviewed on 9 Mar, 2026
Pear Tree Inn St. Louis Near Union Station
This was a wonderful hotel to stay at while we explored the National Parks. We enjoyed the free evening snacks and drinks after a full day at Gateway Arch. Staff were very friendly. The pool was nice. Rooms very clean. Would definitely stop here again.
Reviewed on 14 Mar, 2026
Clayton Plaza Hotel & Extended Stay
Room was clean staff friendly good location Pool was closed though
Reviewed on 15 Mar, 2026
21C Museum Hotel St Louis
Great lock
Reviewed on 15 Mar, 2026
Drury Plaza Hotel St. Louis at the Arch
Great place to stay right next to Gateway Arch National Park. Walkable to other downtown points of interest as well. The happy hour drinks and dinner was a great bonus. Would stay again.
Reviewed on 15 Mar, 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Enterprise Center.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Enterprise Center are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
