Midtown
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's acclaimed theatre scene or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's acclaimed art galleries or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
Downtown St. Louis Smartphone Guided Audio Walking Tour App
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St. Louis Premium Driving Tour with Boat Ride & Arch
St Louis Self-Guided Driving and Walking Audio Tour
Gateway Arch National Park Self Guided Audio Walking Tour
Top hotels in Midtown
Element St. Louis Midtown
We had a great stay at this hotel in January 2026. The staff was very helpful, the rooms were clean and comfortable, and the indoor pool was great for the kids.
Reviewed on 24 Jan, 2026
21C Museum Hotel St Louis
Staff was great!
Reviewed on 25 Jan, 2026
Clayton Plaza Hotel & Extended Stay
Room comfortable and clean. Dtaff very polite, professional, and helpful.
Reviewed on 25 Jan, 2026
Drury Plaza Hotel St. Louis at the Arch
Nice staff, clean rooms, dinner and breakfast for quests.
Reviewed on 25 Jan, 2026
Hyatt Regency St. Louis at The Arch
Great location and vibe. I will definitely return
Reviewed on 23 Jan, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hotel is beautiful and the room was very nice.
Reviewed on 23 Jan, 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
