A coastal fortress with a stone wall and a tiled-roof building.

Find Luxury Hotels in Syracuse

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Syracuse Luxury Hotels

Tonight
19 Aug - 20 Aug
Tomorrow
20 Aug - 21 Aug
This weekend
21 Aug - 23 Aug
Next weekend
28 Aug - 30 Aug

Our top choices for Syracuse luxury hotels

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
S$962
includes taxes & fees
23 Aug - 24 Aug
Grand Hotel Des Ètrangers - The Leading Hotels of the World

2. Minareto

Minareto
Syracuse
  • Syracuse seaside splendour offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
S$769
includes taxes & fees
11 Sept - 12 Sept
Minareto

3. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness centre.
S$565
includes taxes & fees
13 Sept - 14 Sept
Wellness & Spa Hotel Principe di Fitalia

4. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
S$582
includes taxes & fees
20 Aug - 21 Aug
Ortea Palace Hotel, Sicily, Autograph Collection

5. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
S$510
includes taxes & fees
10 Sept - 11 Sept
Grand Hotel Ortigia Siracusa

6. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
S$454
includes taxes & fees
30 Aug - 31 Aug
Dimora Caiammari Luxury Hotel & Spa

7. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
  • Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
S$332
includes taxes & fees
21 Aug - 22 Aug
Algila' Ortigia Charme Hotel

8. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
  • Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
S$400
includes taxes & fees
31 Aug - 1 Sept
Palazzo Artemide - VRetreats, SLH Collection

9. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
  • Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
S$343
includes taxes & fees
25 Aug - 26 Aug
Charme Hotel Henry's House

10. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
S$294
includes taxes & fees
24 Aug - 25 Aug
Caportigia Boutique Hotel
View all properties

Top Syracuse Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Beautiful old world charm.."
NINA 4-night trip
Posted 3 days ago
Grand Hotel Ortigia Siracusa
 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"Absolutely magnificent stay!!!! Surprised no turn down service but otherwise zero complaints!!!"
Annie 4-night trip
Posted 2 weeks ago
Palazzo Artemide - VRetreats, SLH Collection
Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Very nice hotel outside of busy area but easy to access downtown Ortigia and Siracusa Unfortunately was only there for one night but pool looked wonderful and historic ambiance in hotel was interesting to see. Parking was free and breakfast was wonderful with so many options! Will definitely revisit when I’m the area again!"
Giovanna 1-night trip
Posted 2 months ago
Hotel Parco delle Fontane
Grand Hotel Villa Politi

Grand Hotel Villa Politi

10/10 Excellent
"The rooms are really nice, smaller than pictures, but nice. View was ok, small porthole in a Concrete wall. Pool was great, breakfast was amazing. Staff are very friendly and attentive. We had a car so it was 7 minute drive to parking outside Ortigia every evening plus we did day trips to Noto, Catania, Marzemeni, Brucoli. Parking was easy and convenient. Great value for the price. I would stay again. We rented a self captained boat as well, coast is beautiful, and we ate every night in Ortigia. We split our time between Syracusa-Ortigia and Taormina."
Brian 5-night trip
Posted 2 months ago
Grand Hotel Villa Politi

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Syracuse?
Travel to Catania (CTA-Fontanarossa) Airport or Comiso (CIY-Vincenzo Magliocco) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best luxury place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your trip.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To venture out into the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

Explore a world of travel with Expedia