Find Luxury Hotels in Syracuse

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Syracuse Luxury Hotels

This weekend
Next weekend

Our top choices for Syracuse luxury hotels

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.6 out of 10, Exceptional, (73 reviews)
  • cleanliness
    Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
The price is S$949
includes taxes & fees
23 Apr - 24 Apr
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.6 out of 10, Exceptional, (94 reviews)
  • cleanliness
    Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness centre.
The price is S$531
includes taxes & fees
4 May - 5 May
Wellness & Spa Hotel Principe di Fitalia

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.4 out of 10, Exceptional, (259 reviews)
  • cleanliness
    Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
The price is S$583
includes taxes & fees
26 Apr - 27 Apr
Ortea Palace Hotel, Sicily, Autograph Collection

Minareto

Minareto
5.0 star property
Syracuse
8.8 out of 10, Excellent, (267 reviews)
  • cleanliness
    Syracuse seaside splendour offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
The price is S$470
includes taxes & fees
15 Apr - 16 Apr
Minareto

Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (211 reviews)
  • cleanliness
    Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
The price is S$471
includes taxes & fees
7 Apr - 8 Apr
Dimora Caiammari Luxury Hotel & Spa

Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
4.0 star property
Ortigia
9.4 out of 10, Exceptional, (666 reviews)
  • cleanliness
    Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
The price is S$481
includes taxes & fees
13 Apr - 14 Apr
Palazzo Artemide - VRetreats, SLH Collection

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (938 reviews)
  • cleanliness
    Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
The price is S$471
includes taxes & fees
14 Apr - 15 Apr
Algila' Ortigia Charme Hotel

Charme Hotel Henry's House

Charme Hotel Henry's House
4.0 star property
Ortigia
9.6 out of 10, Exceptional, (323 reviews)
  • cleanliness
    Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
The price is S$389
includes taxes & fees
9 Apr - 10 Apr
Charme Hotel Henry's House

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (585 reviews)
  • cleanliness
    Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
The price is S$386
includes taxes & fees
29 Apr - 30 Apr
Grand Hotel Ortigia Siracusa

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (269 reviews)
  • cleanliness
    Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
The price is S$255
includes taxes & fees
14 Apr - 15 Apr
Caportigia Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Syracuse Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Syracuse?
Travel to Catania (CTA-Fontanarossa) Airport or Comiso (CIY-Vincenzo Magliocco) Airport, and then treat yourself to a stay at one of 11 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best luxury place to stay in Syracuse?
Grand Hotel Ortigia Siracusa is a luxury hotel with a private beach and spa services, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Ortea Palace Hotel, Sicily, Autograph Collection and Wellness & Spa Hotel Principe di Fitalia are other upscale choices for your trip.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 11 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Porto Piccolo.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To venture out into the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

Explore a world of travel with Expedia