What's it like in Uptown Central?

Guests are sure to enjoy their time checking out all that San Antonio's Uptown Central neighbourhood has to offer. Are you looking for Uptown Central travel tips? Make sure that you visit Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighbourhood.

What's the best accommodation in Uptown Central?

Based on our traveller data, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is one of the top choices for your stay in Uptown Central. This hotel is a short 14-minute walk from North Star Mall, and it offers free breakfast and an outdoor pool. Other good options for your stay in the area include Wyndham Garden San Antonio Airport and La Quinta Inn & Suites by Wyndham San Antonio Airport .

How many hotels will I be able to find in the Uptown Central area?

Expedia has 388 hotels and other accommodation options in Uptown Central to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Uptown Central, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown Central.

What can I see and do in this San Antonio neighbourhood?

Uptown Central's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighbourhood. A few places to visit in the area around Uptown Central include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. McDermott Center and Gayle and Tom Benson Stadium are also worth a visit when you're out sightseeing in San Antonio.

Top 10 Uptown Central Hotels of 2026

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Our top choices for Uptown Central hotels

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

1. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central

Aaron

includes taxes & fees

30 Sept - 1 Oct

A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

2. Drury Plaza Hotel San Antonio Airport

Uptown Central

Jay

includes taxes & fees

4 Oct - 5 Oct

A breakfast bar with various food items and kitchen appliances.

3. Spark by Hilton San Antonio Airport

Uptown Central

Carla

includes taxes & fees

4 Oct - 5 Oct

A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.

4. Holiday Inn Express San Antonio-Airport by IHG

Uptown Central

Liz

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a beige sofa, a chandelier, a staircase, and a large window overlooking a parking area.

5. Days Inn by Wyndham San Antonio Airport

Uptown Central

Jennifer

includes taxes & fees

4 Oct - 5 Oct

A modern kitchen with a central island, built-in appliances, and a coffee station.

6. Wyndham Garden San Antonio Airport

Uptown Central

SWAROOP JADHAV

includes taxes & fees

11 Oct - 12 Oct

A multi-story hotel with a stone facade, multiple windows, and a sign indicating it is a Homewood Suites Hilton.

7. Homewood Suites by Hilton San Antonio Airport

Uptown Central

Azeneth

includes taxes & fees

3 Oct - 4 Oct

A modern living room with a sofa, coffee table, and a large abstract painting.

8. Marriott San Antonio Airport

Uptown Central

Erika

includes taxes & fees

11 Oct - 12 Oct

A spacious living area with a dark blue sofa, four grey armchairs, and three metallic coffee tables.

9. La Quinta Inn & Suites by Wyndham San Antonio Airport

Uptown Central

Gonzalo

includes taxes & fees

4 Oct - 5 Oct

A modern bar area with seating and a staircase leading to an upper level.

10. Embassy Suites by Hilton San Antonio Airport

Uptown Central

Arianna

includes taxes & fees

4 Oct - 5 Oct

A modern bar area with a long counter, multiple bar stools, and a television screen.

11. Courtyard by Marriott San Antonio Airport

Uptown Central

Rory

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

12. Crowne Plaza San Antonio Airport by IHG

Uptown Central

Jose

includes taxes & fees

25 Oct - 26 Oct

A spacious hotel lobby with a long marble reception desk, multiple seating areas, and a large television screen.

13. Hampton Inn & Suites San Antonio-Airport

Uptown Central

Luis

includes taxes & fees

4 Oct - 5 Oct

A hotel with a modern design, featuring a covered entrance and multiple balconies.

14. Best Western Garden Inn

Uptown Central

Mario De La

includes taxes & fees

10 Oct - 11 Oct

A hotel pool area with two pools, a spa lift, and a wheelchair-accessible sign.

15. Hilton Garden Inn San Antonio Airport South

Uptown Central

min

includes taxes & fees

4 Oct - 5 Oct

A multi-level hotel atrium with a central courtyard, outdoor seating, and a pool.

16. Estancia del Norte San Antonio, Tapestry Collection by Hilton

Uptown Central

Iliana

includes taxes & fees

11 Oct - 12 Oct

A modern interior with a curved ceiling, a sectional sofa, a round coffee table, and a dining area with chairs and a table.

17. SpringHill Suites by Marriott San Antonio Airport

Uptown Central

Perla

includes taxes & fees

1 Oct - 2 Oct

An outdoor patio with metal chairs, a barbecue grill, and string lights.

18. Home2 Suites by Hilton San Antonio Airport, TX

Uptown Central

Glen

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with wicker furniture and a stone fire pit.

19. Residence Inn By Marriott San Antonio Airport/Alamo Heights

Uptown Central

Jill

includes taxes & fees

4 Oct - 5 Oct

A buffet area with a variety of food options, a beverage dispenser, and a fruit bowl.

20. Fairfield Inn & Suites San Antonio Airport/North Star Mall

Uptown Central

jonathan

includes taxes & fees

4 Oct - 5 Oct

View all properties

Compare popular hotels in Uptown Central

Property	Property class	Guest rating
Drury Plaza Hotel San Antonio Airport	3.0 star property	9.4 Exceptional 2,304 reviews	View
Holiday Inn Express San Antonio-Airport by IHG	2.5 star property	9.4 Exceptional 1,005 reviews	View
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham	2.5 star property	9.0 Wonderful 2,249 reviews	View
Estancia del Norte San Antonio, Tapestry Collection by Hilton	3.5 star property	9.0 Wonderful 1,005 reviews	View
Spark by Hilton San Antonio Airport	2.0 star property	8.8 Excellent 1,770 reviews	View

Where to stay in Uptown Central

Find the best Uptown Central areas for the activities you enjoy most.

A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

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A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

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A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

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A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

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A historic stone building with a large wooden door, arched windows, and ornate columns.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

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Top Uptown Central Hotel Reviews

Drury Plaza Hotel San Antonio Riverwalk

10/10 Excellent

"Always a must when we stay in San Antonio."

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

10/10 Excellent

"The lazy river was the highlight of the property for my husband and I. I love the restaurant within the resort JBs I got the two entrees and the two sides it was so good and my husband got the enchiladas which was were great as well! I loved the room itself we loved everything about it."

Red Roof Inn San Antonio - Airport

8/10 Good

"This is one of the better Red Roof properties in the country and the very best in San Antonio. Red Roof Inns provides basic, pet-friendly lodging at a very low nightly rate, but the quality of the rooms and feeling of safety and security vary widely from property to property. I’ve stayed at least 20 Red Roof Inns in 8 states from New Mexico to New York."

Hotels in Uptown Central

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Our top choices for Uptown Central hotels

1. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

2. Drury Plaza Hotel San Antonio Airport

3. Spark by Hilton San Antonio Airport

4. Holiday Inn Express San Antonio-Airport by IHG

5. Days Inn by Wyndham San Antonio Airport

6. Wyndham Garden San Antonio Airport

7. Homewood Suites by Hilton San Antonio Airport

8. Marriott San Antonio Airport

9. La Quinta Inn & Suites by Wyndham San Antonio Airport

10. Embassy Suites by Hilton San Antonio Airport

11. Courtyard by Marriott San Antonio Airport

12. Crowne Plaza San Antonio Airport by IHG

13. Hampton Inn & Suites San Antonio-Airport

14. Best Western Garden Inn

15. Hilton Garden Inn San Antonio Airport South

16. Estancia del Norte San Antonio, Tapestry Collection by Hilton

17. SpringHill Suites by Marriott San Antonio Airport

18. Home2 Suites by Hilton San Antonio Airport, TX

19. Residence Inn By Marriott San Antonio Airport/Alamo Heights

20. Fairfield Inn & Suites San Antonio Airport/North Star Mall

Compare popular hotels in Uptown Central

Where to stay in Uptown Central

Downtown San Antonio

Far West Side

Medical Center District

Northwest Side

Stone Oak

Top Uptown Central Hotel Reviews

Drury Plaza Hotel San Antonio Riverwalk

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