Uptown Holidays
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Top hotels in Uptown
21C Museum Hotel St Louis
Hotel was very quiet and staff helpful and courteous. The coffee shop was great for coffee and breakfast and the rooms were clean with hot water and great water pressure. The only thing I would change was the mattress - bed was very firm, kind of felt like lying on a table. Gallery was a fun feature ...
Reviewed on 3 Feb, 2026
Clayton Plaza Hotel & Extended Stay
Lovely hotel. Great breakfast
Reviewed on 29 Jan, 2026
Hyatt Regency St. Louis at The Arch
Nice room & friendly staff!
Reviewed on 28 Jan, 2026
Popular places to visit
FanDuel Sportsbook and Horse Racing
Why not try your luck with a visit to FanDuel Sportsbook and Horse Racing during your visit to Collinsville? Discover the great live music in this walkable area or seek out the local tours.
Things to do
Best of St. Louis Small Group Tour w/ Arch & River Cruise
St Louis Self-Guided Driving and Walking Audio Tour
Downtown St. Louis Smartphone Guided Audio Walking Tour App
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.