Uruguay Street

Photo by Caitlyn McCrimmon
Photo by Caitlyn McCrimmon
Photo by Caitlyn McCrimmon
Photo by Caitlyn McCrimmon

Popular places to visit

Soho City Center

Soho City Center

You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's casinos or seek out its local tours.

Soho City Center
Avenida Balboa

Avenida Balboa

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Calle 50

Calle 50

You can find out about the history of Panama City when you stop by Calle 50. Discover the area's shops or seek out its local tours.

Calle 50
Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall

Baha’i House of Worship

You can find out about the history of Panama City with a stop at Baha’i House of Worship. Stroll along the seaside or visit the shops in this vibrant area.

Baha’i House of Worship

Top Uruguay Street Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street, Panama City, Panama
Waldorf Astoria Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
Megapolis Hotel Panamá
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52, Aquilino de La Guardia, Panama City, Panama
The Executive Hotel
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50, Bella Vista, Panama City
W Panama
AC Hotel by Marriott Panama City

AC Hotel by Marriott Panama City

3.5 out of 5
Calle Ricardo Arias 14, Campo Alegre Area Bancaria, Panama City
AC Hotel by Marriott Panama City
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 out of 5
Calle 52 and Ricardo Arias, Panama City
Hyatt Regency Panama City
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Decapolis Hotel Panama City
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
See all 1,479 properties in Uruguay Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.