S$591 Cheap Flights from Panama City to San Diego

View S$591 flight on Wed, 3 Sep, 2025Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to San Diego Intl. Airport (SAN)

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Cheap Flights from Panama City to San Diego (PTY-SAN)

Prices were available within the past 7 days and start at S$591 for one-way flights and S$808 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$808 Return, found 11 hours ago
S$808
Return
found 11 hours ago
Select United flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$808 found 11 hours ago
United
Wed, 3 Sep - Mon, 8 Sep
PTY
Panama City
SAN
San Diego
S$900 Return, found 11 hours ago
S$900
Return
found 11 hours ago
Select United flight, departing Wed, 3 Sep from Panama City to San Diego, returning Mon, 8 Sep, priced at S$900 found 11 hours ago
United
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$975 Return, found 11 hours ago
S$975
Return
found 11 hours ago
Select United flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$975 found 11 hours ago
American Airlines
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$982 Return, found 11 hours ago
S$982
Return
found 11 hours ago
Select American Airlines flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$982 found 11 hours ago
United
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$982 Return, found 11 hours ago
S$982
Return
found 11 hours ago
Select United flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$982 found 11 hours ago
American Airlines
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$989 Return, found 11 hours ago
S$989
Return
found 11 hours ago
Select American Airlines flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$989 found 11 hours ago
United
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$1,014 Return, found 11 hours ago
S$1,014
Return
found 11 hours ago
Select United flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$1,014 found 11 hours ago
United
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$1,021 Return, found 11 hours ago
S$1,021
Return
found 11 hours ago
Select United flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$1,021 found 11 hours ago
American Airlines
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$1,029 Return, found 11 hours ago
S$1,029
Return
found 11 hours ago
Select American Airlines flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$1,029 found 11 hours ago
Copa
Wed, 3 Sep - Mon, 8 Sep
PTY
Panama City
SAN
San Diego
S$1,117 Return, found 11 hours ago
S$1,117
Return
found 11 hours ago
Select Copa flight, departing Wed, 3 Sep from Panama City to San Diego, returning Mon, 8 Sep, priced at S$1,117 found 11 hours ago
American Airlines
Wed, 3 Sep - Mon, 8 Sep
PTY
Panama City
SAN
San Diego
S$1,118 Return, found 11 hours ago
S$1,118
Return
found 11 hours ago
Select American Airlines flight, departing Wed, 3 Sep from Panama City to San Diego, returning Mon, 8 Sep, priced at S$1,118 found 11 hours ago
Copa
Wed, 3 Sep - Mon, 8 Sep
PTY
Panama City
SAN
San Diego
S$1,124 Return, found 11 hours ago
S$1,124
Return
found 11 hours ago
Select Copa flight, departing Wed, 3 Sep from Panama City to San Diego, returning Mon, 8 Sep, priced at S$1,124 found 11 hours ago
Copa
Wed, 3 Sep - Mon, 8 Sep
PTY
Panama City
SAN
San Diego
S$1,132 Return, found 11 hours ago
S$1,132
Return
found 11 hours ago
Select Copa flight, departing Wed, 3 Sep from Panama City to San Diego, returning Mon, 8 Sep, priced at S$1,132 found 11 hours ago
Delta
Thu, 11 Sep - Sun, 14 Sep
PTY
Panama City
SAN
San Diego
S$1,164 Return, found 11 hours ago
S$1,164
Return
found 11 hours ago
Select Delta flight, departing Thu, 11 Sep from Panama City to San Diego, returning Sun, 14 Sep, priced at S$1,164 found 11 hours ago

Find the cheapest month to fly from Panama City (PTY) to San Diego (SAN)

October is typically the cheapest month to fly

From S$456 - S$1,398 per traveller.

Graph displaying average flight prices per month

Panama City to San Diego route information
Origin airport
Tocumen Intl.
Destination airport
San Diego Intl.
Airlines serving
American Airlines, Delta, United
Return price
S$807
Distance
4658 km

Perfect flights from Panama City to San Diego

Your Journey from Panama City to San Diego

Start your unforgettable journey with Expedia. Our broad selection of flights from Panama City to San Diego caters to every travel need. Whether you're yearning for a romantic escape, a solo adventure, or a cultural immersion, we've got you covered.
 

Choosing Your Ideal Flight

With Expedia, you have access to a wide range of airlines, including Copa, United, American Airlines, Delta. Our selection of flights from Tocumen Intl. to San Diego Intl. caters to every traveler's requirements, ensuring your journey aligns with your schedule. With options from 20 airlines, you're bound to find the perfect flight.
 

Maximizing Value with Panama City to San Diego Flights

Experience the joy of finding cheap flights from Tocumen Intl. to San Diego Intl. that fit your budget. Keep an eye out for our special deals and discounts, and check our flexible one-way fares from S$591 and roundtrip prices from S$808*.
 

Pre-Flight Essentials

Ensure a smooth journey from Panama City to San Diego with Expedia. From information about check-in times and in-flight amenities to guidance on baggage policies, we provide all the essentials to prepare you for your flight.
 

Experience the Vibrant San Diego

Picture yourself stepping off the plane in San Diego and immersing yourself in the unique atmosphere of . From local markets to cultural festivals, each city offers its distinct charm. Make the most of your trip by exploring local attractions and indulging in the local cuisine. With Expedia, explore all this and more, tailored to your budget.
 

Added Convenience on Your Panama City to San Diego Flight

Traveling with Expedia is more than just a flight. We offer details about in-flight amenities, baggage policies, and more to ensure a smooth and hassle-free journey. Choose from our variety of airlines and embark on a memorable journey from Panama City to San Diego.
 

Beyond the Flight – Exploring San Diego

With Expedia, your adventure extends beyond the flight. Explore San Diego at your own pace by renting a car or booking a hotel. Discover hidden gems off the beaten path and create unforgettable memories.
 

Book Your Flight from Panama City to San Diego with Confidence

Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support make your travel experience seamless and stress-free. Embark on your journey from Panama City to San Diego with confidence. Book your travel arrangements with Expedia today.
 
*Note: Prices may vary based on availability and are subject to change.

Frequently asked questions

How much is a flight from PTY to SAN?
Round-trip journeys from Tocumen Intl. Airport (PTY) to San Diego Intl. Airport (SAN) start from S$808. This figure is based on fares advertised within the last 7 days on Expedia for flights departing within the next year — book now so you don't miss out. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from Panama Airport to San Diego Intl. Airport (SAN)?
We get that life can throw the odd curveball, so we've made it as hassle-free as possible for you to cancel your flight online. Just head to the Customer Service Portal and follow the instructions.
How do I find cheap flights from Panama Airport to San Diego Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for PTY to San Diego Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from Tocumen Intl. Airport (PTY) to San Diego Airport?
With around 4,700 kilometres separating Tocumen Intl. Airport (PTY) and SAN, your flight will be a long one. Pack wisely and make your time in the air more comfortable. Things like warm clothes and some noise-cancelling headphones can make the biggest difference.
Which airlines fly direct from PTY to San Diego Airport?
Direct flights aren't available, so you'll need to make at least one stop between Panama Airport and San Diego Intl. Airport (SAN). Make the most of the layover time to stretch your legs and take a break.
Are Tocumen Intl. Airport (PTY) to San Diego Airport flight tickets cheaper when they're purchased at the last minute?
It is possible to score a fantastic last-minute deal from Tocumen Intl. Airport (PTY) to SAN, but it's also possible to miss out entirely! As many airlines release prices up to a year in advance, it's worth keeping an eye on fares early and being ready to book when you spot a good bargain. Expedia compares air carrier prices and updates flight deals all the time, so you can be certain you're always seeing the latest offers.

Explore a world of travel with Expedia

*Available to Expedia members.