A bench, a bicycle, and a lake surrounded by trees.

Four Star Hotels in Upstate South Carolina

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Check availability on Upstate South Carolina 4 Star Hotels

Tonight
7 Oct - 8 Oct
Tomorrow
8 Oct - 9 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Upstate South Carolina 4-star hotels

A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.
A modern interior with a fireplace, plush seating, and a stone accent wall.
An outdoor dining area with multiple tables and chairs, large windows, and a view of greenery.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
United States
MARIA
S$563
includes taxes & fees
11 Oct - 12 Oct
Grand Bohemian Lodge Greenville, Autograph Collection
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.
A bar with multiple shelves of liquor bottles and glasses hanging above.
A modern living room with a fireplace, seating area, and a bar with shelves of bottles.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.

2. Hotel Hartness

Hotel Hartness
Greenville
United States
Kodjo
S$284
includes taxes & fees
25 Oct - 26 Oct
Hotel Hartness
A hotel facade with arched windows, a fountain, and a sign for "The Westin."
A grand lobby with a chandelier, multiple seating areas, and a checkered floor pattern.
A lobby with patterned flooring, a grand staircase, and elegant furniture.
Meeting facility

3. The Westin Poinsett Greenville

The Westin Poinsett Greenville
Greenville Downtown
United States
Karen
S$248
includes taxes & fees
1 Nov - 2 Nov
The Westin Poinsett Greenville
A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.
A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.
A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.
A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

4. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
Greenville Downtown
United States
Gregory
S$204
includes taxes & fees
1 Nov - 2 Nov
Mint House Greenville Downtown by Kasa
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

5. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Amy
S$210
includes taxes & fees
21 Oct - 22 Oct
The Abernathy of Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

6. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
S$249
includes taxes & fees
31 Oct - 1 Nov
The Shepherd Hotel Downtown Clemson
A bar area with multiple hanging decorative lights, a counter with bar stools, and a seating area with chairs.
A modern building with a large illuminated logo reading "TOPGOLF" on the facade.
A spacious indoor venue with rows of white chairs adorned with purple sashes, large windows, and a modern ceiling design.
A well-furnished living room with a chandelier, wooden furniture, and a view through a window.

7. Greenville Marriott

Greenville Marriott
Greenville
United States
John
S$177
includes taxes & fees
1 Nov - 2 Nov
Greenville Marriott
A white, two-story house with a front porch, surrounded by trees and shrubs.
A bedroom with two beds, a TV, and a fireplace.
A dining area with round tables, black chairs, and white tablecloths.
A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.

8. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
United States
Christine
S$160
includes taxes & fees
30 Oct - 31 Oct
Liberty Hall Bed and Breakfast
A modern building with outdoor seating and a garden.
A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.
A row of modern, two-story buildings with a covered patio area.
A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.

9. The Station by Compo Hotels

The Station by Compo Hotels
Travelers Rest
United States
Anonymous traveller
S$429
includes taxes & fees
13 Oct - 14 Oct
The Station by Compo Hotels
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.
A restaurant with a stone fireplace, hanging crystal chandelier, and multiple dining tables set with white tablecloths and wine glasses.
A bar with a large window view of mountains and a chandelier.

10. Hotel Domestique

Hotel Domestique
Travelers Rest
United States
Chuck
S$589
includes taxes & fees
25 Oct - 26 Oct
Hotel Domestique
A spacious living room with a stone fireplace, wooden beams, and a chandelier.
A modern kitchen with dark wood cabinets, a black refrigerator, a microwave, and a stainless steel sink. There are two bar stools at the island, and a flat-screen TV mounted on the wall.
A modern kitchen with white cabinetry, dark blue walls, and a patterned floor.
A modern kitchen with dark cabinetry, a stainless steel range, and a granite countertop.

11. Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek
Greer
United States
Amanda
Landing Apartments Greer - Sugar Creek
A bedroom with a bed, a chair, and a potted aloe plant on a table.
A multi-story building with a symmetrical facade, large windows, and two flags on top.
A modern kitchen with stainless steel appliances, dark wooden cabinets, a dining table with chairs, and a potted plant.
A modern living room with a flat-screen TV, two leather chairs, a wooden dining table, and a potted plant.

12. Landing Furnished Apartments - Spartanburg, SC

Landing Furnished Apartments - Spartanburg, SC
Spartanburg
Landing Furnished Apartments - Spartanburg, SC
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A cozy living room with a fireplace, leather armchair, and a large window.
A spacious living area with a high ceiling, wooden beams, a grey sofa, a brown leather chair, and a dining table with a plant.
A modern kitchen with stainless steel appliances, a granite countertop, and large windows offering a view of the outdoors.

13. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
Salem
United States
Anonymous traveller
Designer Retreat w/ Pool, Golf + Beach Access!
An indoor swimming pool with clear lanes, a covered roof, and a bench area.
A two-story yellow house with a front porch, surrounded by greenery and a driveway.
Interior
Interior

14. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
Salem
Wooded Keowee Key Retreat Near Golf & Trails
Interior
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, and a sink.
A marina with boats docked, a wooden pier, and a clear sky.
A multi-story hotel with a parking lot and a view of a lake.

15. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
Salem
United States
Kathleen
Lake Keowee Condo w/ Balcony & Resort Amenities!
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
A spacious dining area with a wooden table, chairs, and a chandelier. A cozy seating area with a sofa and chairs is visible in the background.
A multi-story hotel with a parking lot and a view of a lake.
An indoor swimming pool with clear lanes, a covered roof, and a bench area.

16. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
Salem
United States
Shawn
Lake Keowee Condo: Resort Pools & Lake Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A swimming pool with a view of a lake and docked boats.
A dining area with a wooden table and chairs, a kitchen with white cabinets, and a staircase with a white railing.
A marina with boats docked, surrounded by greenery and trees.

17. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
Salem
Salem Vacation Rental w/ Lake Keowee Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A marina with boats docked, a lifeguard station, and a view of a lake surrounded by trees.
A sandy beach with a calm lake surrounded by trees.
An aerial view of a residential area with houses, a golf course, and a lake in the background.

18. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
Salem
Views, Pools & Marina: Lake Keowee Condo!
A wooden gazebo with a roof and a table and chairs inside, surrounded by trees and overlooking a lake.
A spacious hotel lobby with a bar area, seating arrangements, and large windows offering views.
A modern kitchen with a stainless steel sink, pendant lighting, and a view to a living area with a sofa and a staircase.
A modern living room with a sofa, a coffee table, and a fireplace.

19. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
A swimming pool with a view of the lake and docked boats.
A modern living room with a large window, a flat-screen TV, a leather sofa, a coffee table, and a bookshelf.
A modern kitchen with a central island, stainless steel appliances, wooden cabinets, and a window providing natural light.
A spacious living area with a high ceiling, a large window with a view of trees, a kitchen with a bar, and a comfortable seating area with a sofa and ottomans.

20. Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
Salem
Keowee Key Condo w/ Lake Access & Community Pools!
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, sports teams and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
An aerial view of a park with a winding path, trees in autumn colors, and a bridge.
Photo by Visit Greenville, South Carolina

Top Upstate South Carolina Hotel Reviews

Hotel Hartness

Hotel Hartness

10/10 Excellent
"One of my favorite hotels so far. Beautiful grounds and well-appointed rooms. Excellent service. Great trails, beautiful location."
jacques 2-night trip
Posted 2 days ago
Hotel Hartness
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"Fantastic in every way!"
MARIA 1-night trip
Posted 3 days ago
Grand Bohemian Lodge Greenville, Autograph Collection
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

10/10 Excellent
"Three bedroom and two bath unit was beautiful and within 2-3 minute walking distance of the falls and downtown. Easy to book, and the check-in and check-out instructions was easy. Within 6-8 driving minutes to Bon Secours Wellness Arena. Loved our stay."
Marilyn 1-night trip
Posted 4 days ago
Mint House Greenville Downtown by Kasa

Find out more about Upstate South Carolina

Take Your Pick of 4 Star Hotels in Upstate South Carolina

The get-go of any holiday starts with choosing a great spot. Upstate South Carolina has been a popular destination with guests because it offers so much to do and see. But, "location, location, location" applies to more than just what city where your plane lands. Now that you have a feel for the town, it's time you to get to know your new digs.

Accommodations as Picturesque as Upstate South Carolina

Search Expedia.com.sg for the right 4 Star Upstate South Carolina Hotel to suit your fancy. Plenty of these people wrote tips to help you select the accommodation that is the right fit for your holiday.You'll be more than glad to get back to your resort every night. Upstate South Carolina has dozens of good options in the 4-star hotel range that create the ideal getaway.

A stay at one of these lodgings ensure that whether you are just relaxing after a day of checking out Upstate South Carolina or you are ready to lie down for the night, you'll be as comfortable as possible. You won't go without a thing during your stay at one of these accommodations. Visitors have consistently given them high marks for their attentive service. It's no surprise that loads of guests recommend it.

Reserve a 4-Star Hotel in Upstate South Carolina Today!

Your trip to Upstate South Carolina should be one that you'll reminisce over for years to come, and booking a 4-star hotel will help create memories that are incredible. Make sure to make a reservation soon. With so few hotels, and plenty of people desiring to vacation in Upstate South Carolina, you may miss out on your perfect hotel.

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.
  • Search for the lowest price from S$160
What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodation generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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