A historical square with a row of arches and people walking.

Five Star Hotels in Assisi

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Assisi 5 Star Hotels

Tonight
22 Aug - 23 Aug
Tomorrow
23 Aug - 24 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sept - 6 Sept

Our top choices for Assisi 5-star hotels

Couples treatment room(s), sauna, hot tub, Turkish bath/hammam
Couples treatment room(s), sauna, hot tub, Turkish bath/hammam
Garden
Exterior

1. Nun Assisi Relais Spa Museum

Nun Assisi Relais Spa Museum
Assisi Historic Center
United States
alessandro
S$918
includes taxes & fees
28 Aug - 29 Aug
Nun Assisi Relais Spa Museum
View from room
Reception
Meeting facility
Premium bedding, minibar, in-room safe, desk

2. Ascesi Resort

Ascesi Resort
Assisi
United States
Enrique
S$370
includes taxes & fees
23 Aug - 24 Aug
Ascesi Resort
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Assisi.
Giotto Hotel & Spa

Giotto Hotel & Spa

Via Fontebella 41 Assisi PG
S$181
10 Sept - 11 Sept
includes taxes & fees
8.8/10 Excellent! (822 reviews)
Giotto Hotel & Spa
Hotel Fontebella

Hotel Fontebella

25 Via Fontebella Assisi PG
S$154
23 Aug - 24 Aug
includes taxes & fees
Hotel Fontebella
TH Assisi - Hotel Cenacolo

TH Assisi - Hotel Cenacolo

Viale Patrono d'Italia 70 Assisi PG
S$148
24 Aug - 25 Aug
includes taxes & fees
9.2/10 Wonderful! (688 reviews)
TH Assisi - Hotel Cenacolo
Still don't see what you're looking for?
See all properties in Assisi.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Assisi

The pink-stone Basilica of St. Francis houses magnificent frescoes that tell the storey of Italy's patron saint. Climb narrow medieval streets to Rocca Maggiore fortress for panoramic views of Umbria's olive-dotted countryside.

See all hotels in Assisi
A historic town with medieval architecture, including a prominent castle on a hill and a church with a bell tower.

Top Assisi Hotel Reviews

Nun Assisi Relais Spa Museum

Nun Assisi Relais Spa Museum

10/10 Excellent
"My husband & I stayed in Assisi July 2026 for 1 night. The property is lovely - the architecture and history make it special & the staff was very accommodating especially about our room preferences. Although we did not use the hot springs that are in the lower level of the hotel, we did walk through there & it is very Roman like. The bed and linens were comfortable and our room was quiet. My only suggestion would be to expand the breakfast buffet to include more hot dishes, etc. Overall, a wonderful location in the heart of the historic area of Assisi & very walkable to the sites & restaurants."
Corinne Laurance 1-night trip
Posted 3 weeks ago
Nun Assisi Relais Spa Museum

Find out more about Assisi

Stay in Luxury: 5 Star Hotels in Assisi

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Assisi trip. You'll join the multitudes of holidaymakers who have made Assisi so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Assisi and indulge in the finer things in life for a while.

5-Star Hotels in Assisi

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Assisi are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Assisi 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Assisi! Choose one of our Assisi 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

Expedia India is rated 4 stars by Feefo based on 1038 reviews

Frequently asked questions

What are the best 5-star hotels in Assisi?
Offering first-rate amenities and services, Expedia customers rate Nun Assisi Relais Spa Museum as one of the most popular 5-star hotels in Assisi. You'll be immersed in a world of luxury from the minute you step foot into the lobby.
How much does it cost to stay in a 5-star hotel in Assisi?
The amount you pay for a 5-star hotel in Assisi depends on factors such as when you plan to travel and the length of your getaway. Our top tip for bagging the best deal? Use our pricing filters to check out the available accommodation for your preferred dates.
  • Search for the lowest price per night from S$148
What makes a hotel 5 stars in Assisi?
In Assisi, a hotel must provide a certain number of high-end amenities to be designated 5 stars. These can include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their superior standard of service. You can look forward to things like in-room massages, concierge services and nightly turn-down services. Some may even offer thoughtful touches such as welcome gifts.

Explore a world of travel with Expedia