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Hotels near Calle 50

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28 Dec - 29 Dec
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29 Dec - 30 Dec
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2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

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Our top choices for Calle 50 hotels

Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 1.2 km from Calle 50
10.0 out of 10, Exceptional, (139)
"Great hotel fair price"
United States
Santiago
The price is S$221
includes taxes & fees
3 Jan - 4 Jan, 2026
Hyatt Regency Panama City
Outdoor pool, pool umbrellas, pool loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 1 km from Calle 50
9.6 out of 10, Exceptional, (1128)
"The room was clean and the location was great."
United States
Wendy
The price is S$138
includes taxes & fees
2 Jan - 3 Jan, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco, 0.4 km from Calle 50
9.0 out of 10, Wonderful, (1001)
"Staff was very helpful. Great location."
United States
John
The price is S$131
includes taxes & fees
10 Jan - 11 Jan, 2026
Courtyard by Marriott Panama Multiplaza Mall
Outdoor pool, free pool cabanas, pool loungers
Yoo Panama & Arts Tower

Yoo Panama & Arts Tower

Yoo Panama & Arts Tower
3.0 star property
Bella Vista, 1.3 km from Calle 50
9.6 out of 10, Exceptional, (56)
"Ron was amazing and so was the property!"
United States
John
Yoo Panama & Arts Tower
Outdoor pool, pool loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 0.7 km from Calle 50
9.0 out of 10, Wonderful, (4728)
"The rooms were nice and the food was great..great staff!!"
United States
Tffany
The price is S$173
includes taxes & fees
12 Jan - 13 Jan, 2026
Hotel Riu Plaza Panama
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.4 out of 10, Exceptional, (1002)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is S$283
includes taxes & fees
14 Jan - 15 Jan, 2026
Bristol Panama, a Registry Collection Hotel
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (2142)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is S$153
includes taxes & fees
8 Jan - 9 Jan, 2026
Plaza Paitilla Inn Hotel
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (1007)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1616)
"Nice place for the rate."
United States
Raymond
The price is S$83
includes taxes & fees
8 Jan - 9 Jan, 2026
Principe Hotel and Suites
Front of property
Novotel Panama City

Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1043)
"The hotel was very nice and the staff was great."
United States
Cena
The price is S$155
includes taxes & fees
10 Jan - 11 Jan, 2026
Novotel Panama City
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1000)
"I loved my stay! "
United States
Jenniffer Gonzalez De La
The price is S$222
includes taxes & fees
13 Jan - 14 Jan, 2026
Las Americas Golden Tower Panama
Outdoor pool, pool loungers
Gran Evenia Panama

Gran Evenia Panama

Gran Evenia Panama
4.5 star property
El Cangrejo, 1 km from Calle 50
9.2 out of 10, Wonderful, (196)
"The property was conveniently located near shops, restaurants and casinos. The food at breakfast was good. Although the pancakes could be better. "
United States
Nicole
Gran Evenia Panama
Outdoor pool
MARINN PLACE Financial District

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (299)
"Second stay, very nice"
Canada
Xiaozhi
The price is S$158
includes taxes & fees
29 Dec - 30 Dec
MARINN PLACE Financial District
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
El Cangrejo, 1.4 km from Calle 50
9.2 out of 10, Wonderful, (1003)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is S$129
includes taxes & fees
3 Jan - 4 Jan, 2026
TRYP by Wyndham Panamá Centro
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Obarrio, 0.6 km from Calle 50
8.8 out of 10, Excellent, (1001)
"Everything was clean and the staff was very cooperative."
United States
Deangelo
The price is S$225
includes taxes & fees
3 Jan - 4 Jan, 2026
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Terrace/patio
Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel
2.0 star property
Bella Vista, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (9)
"The manager was very nice. Close to some good restaurants."
United States
Brooke
Hostal Familiar Carmencita - Hostel
Exterior
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Campo Alegre, 0.7 km from Calle 50
8.8 out of 10, Excellent, (1003)
"Clean room , friendly staff "
United States
Junique
The price is S$120
includes taxes & fees
16 Jan - 17 Jan, 2026
Holiday Inn Panama Distrito Financiero by IHG
Balcony
Nomada Container Hotel Panama City

Nomada Container Hotel Panama City

Nomada Container Hotel Panama City
3.0 star property
Obarrio, 0.5 km from Calle 50
8.8 out of 10, Excellent, (162)
"Great"
United States
Joel
The price is S$98
includes taxes & fees
30 Dec - 31 Dec
Nomada Container Hotel Panama City
Terrace/patio
Panama House Bed & Breakfast

Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista, 1 km from Calle 50
9.0 out of 10, Wonderful, (185)
"It was a great stay in a great neighborhood with many food and beverage options, fantastic hosts and an interesting mix of people "
Canada
Brad
The price is S$58
includes taxes & fees
3 Jan - 4 Jan, 2026
Panama House Bed & Breakfast
Exterior
Hotel Milan

Hotel Milan

Hotel Milan
3.0 star property
El Cangrejo, 1.3 km from Calle 50
9.0 out of 10, Wonderful, (433)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is S$57
includes taxes & fees
2 Jan - 3 Jan, 2026
Hotel Milan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Calle 50 Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"I will definitely be back ! "
Yolanda 6-night trip
Posted 1 day ago
Hotel Riu Plaza Panama

Hotels near other Calle 50 attractions

You can find Gucci at Luxury Avenue at Multiplaza Mall in Panama City. #LuxuryShopping #LifeatExpedia #PanamaCity
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Multiplaza Pacific Mall

4.4/5 (1,590 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
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Nice building, highlight on Panama's skyline.
Photo by My World
Open Photo by My World

Soho City Center

You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's casinos or seek out its local tours.
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Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 461 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Calle 50?
Hotel Riu Plaza Panama is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and free breakfast. It's located just a short 0.5 mi (0.7 km) from Calle 50. Other good choices within a short distance include Las Americas Golden Tower Panama and Megapolis Hotel Panamá.
How many hotels can I expect to find near Calle 50?
Expedia has 461 hotels and other accommodation options within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Calle 50.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and Colonial Religious Art Museum. Iglesia del Carmen, Panama Viejo and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle and Anita Villalaz Theater.
How can I get to Calle 50?
Nearby metro stations include Iglesia del Carmen Station and Vía Argentina. If you'd like to explore farther outside of the area, you may want a car rental for your journey.