Calle 50
Visit Calle 50
Tours & day trips
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Catapult Tour Panama
Private & custom tours
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Jungle quad bike Waterfall and Zipline Adventure from Panama City
Cruises & boat tours
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Full-Day Catamaran Sailing Caribbean Beaches with Snorkelling and Lunch
Classes & workshops
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Learn about Panama cocoa and create your own chocolate bar
Air, helicopter & balloon tours
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Charter Flights Panama City
Popular places to visit
Soho City Center
You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's shops or seek out its local tours.
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Bingo 90
Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the casinos and shops in this vibrant area.
National Shrine of the Heart of Mary
You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the shops in this vibrant area.
Top Calle 50 Hotel Deals
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- More Hotel Options in Calle 50
- Courtyard by Marriott Panama Multiplaza Mall
- Las Americas Golden Tower Panama
- Sheraton Grand Panama
- Holiday Inn Panama Distrito Financiero by IHG
- W Panama
- The Executive Hotel
- AC Hotel by Marriott Panama City
- TRYP by Wyndham Panamá Centro
- Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
- Riande Urban Hotel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.