𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Commerce (2026)

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Our top choices for Commerce hotels

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

Rebecca

S$144

includes taxes & fees

19 Nov - 20 Nov

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

2. Drury Inn & Suites Cape Girardeau

Cape Girardeau

DENNIS

S$130

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

3. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

S$146

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

4. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Troy

S$104

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

5. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Chris

S$144

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A hotel room with two beds, a desk, a chair, and a view of the city.

6. The Riverview

Cape Girardeau

Scotty

S$147

includes taxes & fees

22 Oct - 23 Oct

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

7. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Brittany

S$153

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A spacious living room with a sofa set, a coffee table, and a dining area.

A lobby with seating areas, a reception desk, and a bar.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

8. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

S$181

includes taxes & fees

1 Nov - 2 Nov

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

9. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

S$130

includes taxes & fees

26 Oct - 27 Oct

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

10. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

S$111

includes taxes & fees

15 Nov - 16 Nov

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

An outdoor patio with tables and chairs, a stone wall, and large windows.

11. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

S$111

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

12. Drury Inn & Suites Sikeston, MO

Sikeston

Tim

S$138

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

13. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

S$105

includes taxes & fees

9 Nov - 10 Nov

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

14. Quality Inn Cape Girardeau North

Cape Girardeau

Dayanita

S$86

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

A reception area with a counter, a flat-screen TV, and a window with blinds.

15. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

S$85

includes taxes & fees

25 Oct - 26 Oct

A building with a fountain and flower beds in front.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

16. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

S$95

includes taxes & fees

22 Oct - 23 Oct

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with a desk, chair, television, and a lamp.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

17. Quality Inn Cairo I-57

Cairo

Santiago

S$97

includes taxes & fees

13 Nov - 14 Nov

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

18. Town House Inn Cape Giradreau

Cape Girardeau

Hope

S$105

includes taxes & fees

21 Oct - 22 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

A reception area with a counter, a coffee machine, and seating.

A bathroom with a bathtub, toilet, and shower curtain.

19. Country Yard Inn and Suite

Sikeston

William

S$83

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

20. Eagle Inn Charleston

Charleston

Jackson

S$95

includes taxes & fees

22 Oct - 23 Oct

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Top Commerce Hotel Reviews

Quality Inn Cape Girardeau North

10/10 Excellent

"I chose this motel due to it being close to the car rental agency I used and the bus stop for Greyhound. Sidewalks on Kingshighway would have helped but that is on the city of Cape Girardeau! :-}"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Stayed here for a long weekend motorcycle trip. The hotel is conveniently located near many shopping and dining choices. The room was basic but clean and quiet, and lots of channels on the tv! Staff were super friendly and helpful. I will definitely stay here again the next time I am in Cape Girardeau."

Hampton Inn Cape Girardeau I 55 East

10/10 Excellent

"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."

Town House Inn Cape Giradreau

8/10 Good

"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."

Tru By Hilton Cape Girardeau

10/10 Excellent

"A new property that is very clean and well trained staff"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"We have stayed here frequently. Great place to stay."

Comfort Suites Jackson-Cape Girardeau

10/10 Excellent

"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"I was surprised how reasonable the cost was considering how clean & nice all of the finishers were."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."

More cheap stays in Commerce