𝗧𝗢𝗣 𝟭𝟬 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Commerce (2026)

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Commerce

Pet friendly

Apartment

Condo

Pool

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Commerce hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

S$143

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

2. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Raidas

S$103

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

S$146

includes taxes & fees

7 Sept - 8 Sept

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

4. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Cheryl

S$129

includes taxes & fees

13 Sept - 14 Sept

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

5. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Chevonne

S$145

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A spacious living room with a sofa set, a coffee table, and a dining area.

A lobby with seating areas, a reception desk, and a bar.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

6. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

S$180

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

7. The Riverview

Cape Girardeau

Alyssa

S$152

includes taxes & fees

7 Sept - 8 Sept

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

An outdoor patio with stone walls, wicker furniture, and large windows.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

8. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

S$151

includes taxes & fees

13 Sept - 14 Sept

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

An outdoor patio with tables and chairs, a stone wall, and large windows.

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

crystal

S$127

includes taxes & fees

7 Sept - 8 Sept

A modern retail area with a display of local items and snacks.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

10. Tru By Hilton Cape Girardeau

Cape Girardeau

Darlene

S$129

includes taxes & fees

20 Sept - 21 Sept

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

11. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

S$124

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with a desk, chair, television, and a lamp.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

12. Quality Inn Cairo I-57

Cairo

Sharon

S$98

includes taxes & fees

2 Oct - 3 Oct

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A bathroom with a marble wall and a white bathtub.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

13. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

S$111

includes taxes & fees

6 Sept - 7 Sept

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

14. Drury Inn & Suites Sikeston, MO

Sikeston

Scott Andrew

S$137

includes taxes & fees

14 Sept - 15 Sept

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

15. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

S$109

includes taxes & fees

4 Oct - 5 Oct

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

16. Quality Inn Cape Girardeau North

Cape Girardeau

Stephen

S$88

includes taxes & fees

4 Oct - 5 Oct

A building with a fountain and flower beds in front.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

17. The Riverstone Hotel Charleston-Sikeston

Charleston

Bobby

S$94

includes taxes & fees

7 Sept - 8 Sept

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a counter, a flat-screen TV, and a window with blinds.

18. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

France

S$84

includes taxes & fees

8 Sept - 9 Sept

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

19. Eagle Inn Charleston

Charleston

Jackson

S$108

includes taxes & fees

7 Sept - 8 Sept

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A reception area with a counter, a coffee machine, and seating.

A bathroom with a bathtub, toilet, and shower curtain.

20. Country Yard Inn and Suite

Sikeston

William

S$89

includes taxes & fees

7 Sept - 8 Sept

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Commerce Hotel Reviews

The Riverview

10/10 Excellent

"."

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent

"Todo me gustó lindo estar ahy"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Nice place"

The Riverstone Hotel Charleston-Sikeston

10/10 Excellent

"Staff was excellent. Check in was quick. Rooms were clean."

Town House Inn Cape Giradreau

8/10 Good

"The outside needed cleaning, but the room was very clean and well maintained."

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"This was a great place to stay. Everything about it was fantastic. We especially enjoyed the free breakfast and dinner!"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Clean room friendly staff"

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Very nice and clean property."

Tru By Hilton Cape Girardeau

10/10 Excellent

"Clean, quiet - and EV chargers both on and adjacent (Tesla Supercharger) to hotel property."

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

S$84

8 Sept - 9 Sept

includes taxes & fees

6.8/10 (663 reviews)

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

S$88

4 Oct - 5 Oct

includes taxes & fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

S$103

13 Sept - 14 Sept

includes taxes & fees

9.2/10 Wonderful! (1,002 reviews)

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

S$124

4 Oct - 5 Oct

includes taxes & fees

8/10 Very good! (1,000 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

S$129

20 Sept - 21 Sept

includes taxes & fees

9.6/10 Exceptional! (175 reviews)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

S$146

7 Sept - 8 Sept

includes taxes & fees

Frequently asked questions

What's the best place to stay in Commerce?

Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are The Riverview and Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG. See all available top hotels, or vacation rentals in Commerce.

If I need to cancel my hotel reservation in Commerce, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.

How is it to stay in Commerce?

Travellers to Commerce will find plenty to explore and enjoy. There are 88 hotels and other accommodation options in the surrounding area. Find out more about Commerce.

What should I see while I'm in Commerce?

A favourite place to visit is Mississippi River. You'll also find Century Casino & Hotel Cape Girardeau and Show Me Center in the area. Take a look at what more there is to see and do in Expedia's Commerce guide.

What's the seasonal weather in Commerce?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Commerce is 1491 mm.

Commerce Hotels from S$84

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Commerce

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Commerce hotels

1. Drury Plaza Hotel Cape Girardeau Conference Center

2. Pear Tree Inn Cape Girardeau West

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

4. Drury Inn & Suites Cape Girardeau

5. Fairfield Inn & Suites by Marriott Cape Girardeau

6. Courtyard by Marriott Cape Girardeau Downtown

7. The Riverview

8. Hampton Inn Cape Girardeau I 55 East

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10. Tru By Hilton Cape Girardeau

11. Candlewood Suites Cape Girardeau by IHG

12. Quality Inn Cairo I-57

13. Town House Inn Cape Giradreau

14. Drury Inn & Suites Sikeston, MO

15. Comfort Suites Jackson-Cape Girardeau

16. Quality Inn Cape Girardeau North

17. The Riverstone Hotel Charleston-Sikeston

18. Super 8 by Wyndham Charleston/Sikeston East MO

19. Eagle Inn Charleston

20. Country Yard Inn and Suite

Top Commerce Hotel Reviews

The Riverview

Super 8 by Wyndham Charleston/Sikeston East MO

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

The Riverstone Hotel Charleston-Sikeston

Town House Inn Cape Giradreau

Drury Plaza Hotel Cape Girardeau Conference Center

Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Sikeston, MO

Tru By Hilton Cape Girardeau

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app