Mississippi River
Visit Mississippi River
Tours & day trips
See all 577 activities
Swamp & Bayou Tour with Optional Transport from New Orleans
Private & custom tours
See all 94 activities
Airboat Adventures: Semi-Private Airboat Experience
Food, drink & nightlife
See all 88 activities
Paddlewheeler Creole Queen Evening Jazz Cruise
Holiday & seasonal tours
See all 32 activities
New Orleans: French Quarter Ghost Tour with Interior Visit
Adventure & outdoor
See all 23 activities
Mall of America: Moose Mountain Adventure Golf Ticket
Popular places to visit
Mark Twain Memorial Lighthouse
You can find out about the history of Hannibal with a trip to Mark Twain Memorial Lighthouse. While in this walkable area, you can savour the top-notch restaurants.
Mark Twain Cave
You can find out about the history of Hannibal with a visit to Mark Twain Cave. While in this family-friendly area, you can savour the top-notch restaurants.
Sawyer's Creek Fun Park
Explore the great outdoors at Sawyer's Creek Fun Park, a lovely green space in Hannibal. While in this walkable area, you can savour the top-notch restaurants.
Lovers Leap
Find out about the history of Hannibal when you spend time at Lovers Leap. While in this walkable area, you can savour the top-notch restaurants.
Sodalis Nature Preserve
Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.
Dempsey Dog Park
After visiting Dempsey Dog Park, make a plan to see the other sights and activities in Hannibal. While in this family-friendly area, you can savour the top-notch restaurants.
Top Mississippi River Hotel Deals
Check availability on hotels close to Mississippi River
Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station
Hollywood Casino & Hotel St. Louis
21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Live by Loews - St.Louis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Book Flight + Lodging, save up to 100% of flight price - Savings based on flight + lodging package prices as compared to the price of the same components available for booking separately before all discounts and rewards applied. Your bundled savings cover up to 100% of your flight. Savings vary based on origin/destination, length of trip, stay dates and travel suppliers. Savings not available on all flight + lodging package bookings.