Hotels near Mississippi River

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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (363 reviews)
"Friendly, clean, comfortable, nice view of the Mississippi river"
United States
Greg
The price is S$116
includes taxes & fees
5 May - 6 May
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (22 reviews)
"Room was spacious and clean. Had a great stay. The restaurant was delicious. "
United States
James
The price is S$138
includes taxes & fees
4 May - 5 May
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (762 reviews)
"This was a nice area would like to go back and go through the town and do a river boat cruise "
United States
Samantha
The price is S$98
includes taxes & fees
10 May - 11 May
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,005 reviews)
"We loved how convenient the hotel was to Main street. Loved the 3rd floor room that overlooked the Mississippi R.."
United States
Robert
The price is S$161
includes taxes & fees
6 May - 7 May
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (171 reviews)
"Beautiful view of the Mississippi River "
United States
Philip
The price is S$264
includes taxes & fees
4 May - 5 May
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
"Great choices for a continental breakfast!!"
United States
Jeanne
The price is S$174
includes taxes & fees
17 May - 18 May
Sleep Inn & Suites Hannibal West

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"You want to pay more for a fancy hotel? Go right ahead. This is a no frills hotel with clean rooms and comfortable beds. The front desk and housekeeping are friendly and accommodating. We were in town for a family reunion. Several members of our family stayed here and like it as well. We would stay here again! "
United States
Lanette
The price is S$105
includes taxes & fees
25 May - 26 May
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (533 reviews)
"At no point did I think "this place is gross"; the shower was fairly warm; most of the lights worked; the bed was totally decent. That's a 5 star experience at this price point"
United States
Daniel
The price is S$101
includes taxes & fees
4 May - 5 May
Economy Inn Wentzville

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (26 reviews)
"Location is excellent! Close to historic downtown but far enough away to be quiet and peaceful! Very clean and decor is wonderful!"
United States
Tanya
The price is S$264
includes taxes & fees
4 May - 5 May
Lighthouse Inn & Suites

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,002 reviews)
"Friendly staff. Good location"
United States
James
The price is S$92
includes taxes & fees
4 May - 5 May
Relax Inn Saint Charles

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very good, (43 reviews)
"Like: Quiet neighborhood, walkable to places to eat, shop and riverboat cruise & trolley, breakfast optional. Slight inconveniences: Bathroom i unattached to room, shower stall small, distant train whistles as they passed between river and B & B 5 blocks away."
United States
Randolph
The price is S$157
includes taxes & fees
5 May - 6 May
Garden House Bed and Breakfast

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (689 reviews)
"Beds comfortable- nice breakfast choices. A pleasant peaceful setting "
United States
Wanda J
The price is S$142
includes taxes & fees
17 May - 18 May
Comfort Inn & Suites - Hannibal

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,002 reviews)
"Everything was great. Clean hotel and friendly staff. Pool was great. Had to go to front desk for pool towels. "
United States
Lee
The price is S$130
includes taxes & fees
31 May - 1 Jun
Quality Inn & Suites Hannibal West

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,000 reviews)
"Staff was great and the room was clean. Water could have been hotter "
United States
Cameron
The price is S$95
includes taxes & fees
25 May - 26 May
Motel 6 Hannibal, MO

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,002 reviews)
"very friendly staff. Convenient location. Quiet. We will stay there again."
United States
Thomas
The price is S$103
includes taxes & fees
10 May - 11 May
Days Inn by Wyndham St Peters/St Charles

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (508 reviews)
" Very clean-nice room. Breakfast was just o k. Good location downtown but a little noisy being right on main street. Great place for the price. "
United States
Dan
The price is S$119
includes taxes & fees
4 May - 5 May
Baymont by Wyndham Keokuk

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (47 reviews)
"It was my first time to this establishment. It was just a spur of the moment getaway from the kiddos and life. They were undergoing construction when we were there. It was a little messy but the staff were the nicest people you could ask for. Very attentive and helpful. Our room was clesn and comfortable and the scenery out the window wss great. This place has excellent potential. 👌. "
United States
Michael
The price is S$91
includes taxes & fees
10 May - 11 May
LAKEVIEWINN

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,001 reviews)
" Pool closed "
United States
Stephen
The price is S$93
includes taxes & fees
10 May - 11 May
Super 8 by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (165 reviews)
"The gentleman at the front desk was extremely nice and did everything to make my stay wonderful. The breakfast was awesome. The pool was sooo nice. The exercise room was great. I cannot say anything bad about this hotel. This was the first time I stayed here and I will be coming back every three months.!"
United States
Shawn
The price is S$97
includes taxes & fees
10 May - 11 May
Howard Johnson BY Wyndham Hannibal

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,002 reviews)
"The staff was phenomenal & the place was awesome. I will be recommending people here"
United States
Sonja
The price is S$119
includes taxes & fees
11 May - 12 May
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
363 reviews
View
Lunch and dinner served, Italian cuisine
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
22 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
762 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,005 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
171 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Pear Tree Inn St. Louis Airport.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.