Darlington County Hotels: Top Hotel and Accommodation Destinations in Darlington County | Expedia

Stays
Flights
Cars
Packages
Things to do

Deals
Groups & meetings

Open app
List your property
Support
Trips
Unlock instant savings with Member Prices
- Sign in
- Learn more about One Key
- Feedback

Darlington County
South Carolina
United States of America
Hotels
Expedia.com.sg

Holiday Rentals in Darlington County Darlington County Car Hire Darlington County Holidays

Lodging Image

Lodging Image

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Top Cities in Darlington County

A wooden boardwalk along a calm lake surrounded by trees with autumn foliage.

A crowded racetrack at sunset with a large audience.

Check prices for these dates

Tonight

Tomorrow

10 Oct - 11 Oct

This weekend

Next weekend

16 Oct - 18 Oct

Filter by

Star rating

1 star

2 stars

3 stars

4 stars

5 stars

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Good 7+

Very good 8+

Wonderful 9+

Any

Our top choices for Darlington County hotels

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

1. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property

Florence

9.0 out of 10, Wonderful, (2,461 reviews)

9.0/10

Wonderful

(2,461 reviews)

"Great location, friendly staff."

"Great location, friendly staff."

United States

Windia

The price is S$128

S$128

includes taxes & fees

11 Oct - 12 Oct

Park Inn by Radisson Florence, SC

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

2. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 star property

Florence

8.2 out of 10, Very good, (314 reviews)

8.2/10

Very good

(314 reviews)

The price is S$126

S$126

includes taxes & fees

25 Oct - 26 Oct

Spark by Hilton Florence North I-95, SC

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

3. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property

Florence

8.6 out of 10, Excellent, (2,739 reviews)

8.6/10

Excellent

(2,739 reviews)

The price is S$93

S$93

includes taxes & fees

11 Oct - 12 Oct

Howard Johnson by Wyndham Florence

A hotel lobby with a reception desk, seating area, and a television screen.

A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

4. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property

Florence

9.0 out of 10, Wonderful, (1,366 reviews)

9.0/10

Wonderful

(1,366 reviews)

"Breakfast was excellent. Room was clean and quiet."

"Breakfast was excellent. Room was clean and quiet."

United States

Mila

The price is S$145

S$145

includes taxes & fees

1 Nov - 2 Nov

Comfort Inn & Suites Florence Center Area

A hotel room with a desk, chair, bed, and a yellow sofa.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.

A swimming pool with lounge chairs and a building with balconies.

5. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property

Florence

8.4 out of 10, Very good, (387 reviews)

8.4/10

Very good

(387 reviews)

"Nice spot for an overnight!"

"Nice spot for an overnight!"

United States

Sharhonda

The price is S$126

S$126

includes taxes & fees

20 Oct - 21 Oct

Quality Inn & Suites Florence Civic Center

A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.

A modern hotel room with a large bed, two armchairs, a desk with a computer, and a decorative wall.

A lobby with a reception desk, seating area, and artwork on the walls.

A modern kitchen with a central island, a dining area with chairs, a large window with a view of palm trees, and a flat-screen TV mounted on the wall.

6. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property

Florence

7.2 out of 10, Good, (1,006 reviews)

7.2/10

Good

(1,006 reviews)

"Clean and easy access to restaurants"

"Clean and easy access to restaurants"

United States

Jefferson

The price is S$93

S$93

includes taxes & fees

15 Oct - 16 Oct

Days Inn by Wyndham Florence Near Civic Center

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

Property amenity

7. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property

Florence

8.2 out of 10, Very good, (1,003 reviews)

8.2/10

Very good

(1,003 reviews)

"The room Was clean and comfortable and the breakfast was good."

"The room Was clean and comfortable and the breakfast was good."

United States

John

The price is S$140

S$140

includes taxes & fees

18 Oct - 19 Oct

SpringHill Suites by Marriott Florence

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

A modern lounge area with brick walls, large windows, and contemporary furniture.

8. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property

Florence

9.0 out of 10, Wonderful, (1,000 reviews)

9.0/10

Wonderful

(1,000 reviews)

"Convenient hotel, clean and near restaurant options."

"Convenient hotel, clean and near restaurant options."

United States

Ivette

The price is S$143

S$143

includes taxes & fees

2 Nov - 3 Nov

Hyatt Place Florence Downtown

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A coffee station with two coffee machines and a display of coffee pods and cups.

A hotel pool area with two pools, a lifeguard stand, and a towel service station.

A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

9. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property

Florence

9.0 out of 10, Wonderful, (1,001 reviews)

9.0/10

Wonderful

(1,001 reviews)

"Wonderful hotel and in a great location!"

"Wonderful hotel and in a great location!"

United States

Leigh

The price is S$164

S$164

includes taxes & fees

18 Oct - 19 Oct

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A lobby with a fireplace, seating area, and a television.

A hotel lobby with a reception desk, seating area, and a welcome mat.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

10. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 star property

Florence

9.0 out of 10, Wonderful, (978 reviews)

9.0/10

Wonderful

(978 reviews)

"We loved our stay at the Hampton Inn. The room had plenty of space and was clean. The staff was friendly and they had a lot of options at breakfast. We would definitely stay there again."

"We loved our stay at the Hampton Inn. The room had plenty of space and was clean. The staff was friendly and they had a lot of options at breakfast. We would definitely stay there again."

United States

Ryan

The price is S$163

S$163

includes taxes & fees

18 Oct - 19 Oct

Hampton Inn & Suites Florence Center

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

An outdoor kitchen area with a grill, a pool, and a covered seating area.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

A conference room with round tables, chairs, and a carpeted floor.

11. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3.0 star property

Florence

9.4 out of 10, Exceptional, (1,002 reviews)

9.4/10

Exceptional

(1,002 reviews)

The price is S$194

S$194

includes taxes & fees

1 Nov - 2 Nov

Staybridge Suites Florence - Civic Center by IHG

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

A modern lounge area with a sofa, armchairs, and small tables.

A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

12. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3.0 star property

Florence

9.0 out of 10, Wonderful, (911 reviews)

9.0/10

Wonderful

(911 reviews)

"The staff was amazing!!! The rooms are impeccable the kitchen is excellent!!! I would love to stay here every time"

"The staff was amazing!!! The rooms are impeccable the kitchen is excellent!!! I would love to stay here every time"

United States

Crystal

The price is S$157

S$157

includes taxes & fees

2 Nov - 3 Nov

TownePlace Suites by Marriott Florence

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

A modern coffee station with a counter, coffee machines, and a seating area with chairs.

An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

13. Comfort Suites Florence I-95

Comfort Suites Florence I-95

2.5 star property

Florence

8.2 out of 10, Very good, (1,001 reviews)

8.2/10

Very good

(1,001 reviews)

"Very convenient to highway"

"Very convenient to highway"

United States

Denise

The price is S$142

S$142

includes taxes & fees

18 Oct - 19 Oct

Comfort Suites Florence I-95

A swimming pool with lounge chairs and a building with a sign reading "BAYMONT".

A modern living room with a sectional sofa, a coffee table, and a flat-screen TV mounted on the wall.

A hotel room with a large bed, a desk, a chair, a TV, and a painting of a waterfall on the wall.

A motel with a covered parking area, a gas station sign, and a row of rooms with balconies.

14. Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

2.0 star property

Florence

7.2 out of 10, Good, (1,004 reviews)

7.2/10

Good

(1,004 reviews)

"Great and affordable stay"

"Great and affordable stay"

United States

Shawn

The price is S$78

S$78

includes taxes & fees

15 Oct - 16 Oct

Super 8 by Wyndham Florence

A hotel room with a bed, bedside table with a phone, a desk with a chair, a TV mounted on the wall, and a window with curtains.

A reception area with a wooden counter, a seating area with tables and chairs, and a large window with a view.

A modern kitchen with dark wood cabinets, stainless steel appliances, and a large juice dispenser.

A conference room with a wooden table, chairs, a TV, and a computer on a shelf.

15. Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2.0 star property

Florence

7.0 out of 10, Good, (1,000 reviews)

7.0/10

Good

(1,000 reviews)

"I enjoyed my stays"

"I enjoyed my stays"

United States

Carletta

The price is S$80

S$80

includes taxes & fees

26 Oct - 27 Oct

Microtel Inn & Suites by Wyndham Florence

A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.

A hotel room with a bed, sofa, TV, and a desk.

A hotel room with a bed, a sofa, a desk, and a TV.

16. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3.0 star property

Florence

7.8 out of 10, Good, (1,484 reviews)

7.8/10

Good

(1,484 reviews)

The price is S$123

S$123

includes taxes & fees

18 Oct - 19 Oct

La Quinta Inn & Suites by Wyndham Florence

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

An outdoor patio area with brick walls, a fire pit, and outdoor seating.

17. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

2.5 star property

Florence

8.6 out of 10, Excellent, (1,000 reviews)

8.6/10

Excellent

(1,000 reviews)

The price is S$182

S$182

includes taxes & fees

12 Oct - 13 Oct

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

A restaurant with brick walls, framed awards, and a bar area.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

A bar area with a curved counter, multiple stools, and a brick wall backdrop.

18. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3.0 star property

Florence

8.8 out of 10, Excellent, (657 reviews)

8.8/10

Excellent

(657 reviews)

"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"

"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"

United States

Ankh

The price is S$165

S$165

includes taxes & fees

1 Nov - 2 Nov

Hotel Florence, Tapestry Collection by Hilton

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

19. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 star property

Florence

8.6 out of 10, Excellent, (1,002 reviews)

8.6/10

Excellent

(1,002 reviews)

"Excellent quick stay while traveling. Very clean room and easy check in and out."

"Excellent quick stay while traveling. Very clean room and easy check in and out."

United States

Tiffany

The price is S$153

S$153

includes taxes & fees

15 Oct - 16 Oct

Tru by Hilton Florence I-95

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

A corridor with shelves stocked with snacks and a frozen food display.

20. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 star property

Florence

9.0 out of 10, Wonderful, (991 reviews)

9.0/10

Wonderful

(991 reviews)

The price is S$175

S$175

includes taxes & fees

15 Oct - 16 Oct

Hampton Inn & Suites Florence-North-I-95

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Sign up, it's free

Top Darlington County Hotel Reviews

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

10/10 Excellent

"Room was very clean"

Christopher 1-night trip

Posted 1 hour ago

TownePlace Suites by Marriott Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"Room was very clean and well presented. Bathroom was large and well stocked with extra tissue, towels, and shower had complementary shampoo, body wash and conditioner. Room had mini fridge and microwave. Large screen tv with all needed channels plus HBO. Breakfast buffet was excellent as well as all staff present. A very big bonus for us is the place is PET FRIENDLY!!! We will be back!"

Lester 1-night trip

Posted 11 hours ago

La Quinta Inn & Suites by Wyndham Florence

Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent

"Everything was excellent- the staff, the rooms, the parking, you name it. Very satisfied"

Mary 1-night trip

Posted 14 hours ago

Comfort Suites Florence I-95

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent

"Overview... it was Excellent. Clean, very comfortable spacious and convenient to restaurants. Staff was helpful and nice. Updates were very nice.Would definitely stay again."

Barbara 1-night trip

Posted 18 hours ago

Spark by Hilton Florence North I-95, SC

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

8/10 Good

"Nothing to say"

jun 1-night trip

Posted 1 day ago

Comfort Inn & Suites Florence Center Area

The Mantissa Hotel

The Mantissa Hotel

10/10 Excellent

"Property has lots of character and charm. Staff were helpful and very pleasant. The room was quite large and clean. The bed was comfortable."

Marilyn 1-night trip

Posted 4 days ago

The Mantissa Hotel

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

8/10 Good

"n/a"

Timothy 2-night trip

Posted 2 weeks ago

Fairfield Inn by Marriott Hartsville

The Landmark Inn

The Landmark Inn

8/10 Good

"Room was very nice, comfortable beds. Coffee only in lobby. Staff was great"

Tammie 3-night trip

Posted 1 month ago

The Landmark Inn

Quality Inn Hartsville

Quality Inn Hartsville

10/10 Excellent

"I enjoy my stay everything was so convenient. I wouldn't change a thing"

Christopher 4-night trip

Posted 3 months ago

Quality Inn Hartsville

Explore a world of travel with Expedia

Accommodation
Flights
Packages
Cars
Explore a world of travel with Expedia

Flights to Florence
Flights to Loris
Flights to Manning
Flights from Alcolu
Flights from Hamer
Flights from Loris
Flights from Patrick
Flights from Horry County
Flights from Manning
Flights from Charleston (CHS) to Cheraw (HCW)
Flights from Charlotte (CLT) to Cheraw (HCW)
Flights from Dillon (DLL) to Cheraw (HCW)
Flights from Greenville (GDC) to Cheraw (HCW)
Flights from Indianapolis (IND) to Cheraw (HCW)
Flights from New York (LGA) to Cheraw (HCW)
Flights from Istanbul (SAW) to Florence (FLO)
Flights from Singapore (SIN) to Florence (FLO)

Cades Holidays
Visit Cades
Visit Cane Savannah
Visit Dalzell
Florence National Cemetery
Florence Holidays
Francis Marion University
Visit Galivants Ferry
H Cooper Black Jr. Memorial Field Trial & Recreation Area
Visit Hamer
Visit Kershaw
Latta Holidays
Visit Manning
Visit Mccoll
Shaw Air Force Base
Sumter Mall
Visit Sumter

Alamo Rent A Car Rental Cars in Lancaster County
Enterprise Rental Cars in Elgin
Global Rent a Car Rental Cars in Lamar
Hertz Rental Cars in Shaw Air Force Base

Book Hotels in Darlington County on Expedia.com

Go further with the Expedia app

Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app

QR code to download the app

Company

About
Jobs
List your property
Partnerships
Affiliate Marketing
Newsroom

Explore

Singapore travel guide
Hotels in Singapore
Holiday packages in Singapore
Car hire in Singapore
All accommodation types
Travel blog
Rewards with One Key™

Policies

Privacy
Terms of use
Cookies
One Key™ terms and conditions
Vrbo terms and conditions
Legal information / Contact us
Content guidelines and reporting content

Help

Support
Change or cancel your booking
Refund process and timelines
Book a flight using an airline credit
International travel documents

© 2026 Expedia, Inc., an Expedia Group company. All rights reserved. Expedia and the Expedia Logo are trademarks or registered trademarks of Expedia, Inc.

Singapore Travel Licence No. TA03984 held by Expedia Services Singapore Pte. Ltd. Customer Support: +65 6415 5555

4af1e65c-3a52-4368-8bab-21fd9712d66491641149-884f-4614-b44a-b8998ef2e961