Top 10 Greater South Side Hotels of 2026

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Where to stay in Greater South Side

Find the best Greater South Side areas for the activities you enjoy most.

Downtown Des Moines

The abundant dining options and live music are top of the list for many visitors to Downtown Des Moines. A stop by 801 Grand or Des Moines Civic Center might round out your trip.

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Historic East Village

Find beautiful government buildings, cultural attractions and a garden oasis in this older section of the city extending along a pretty riverfront.

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Court District

Travellers come to Court District for its abundant dining options, and you can see top attractions like Science Center of Iowa and Principal Park while you're in town.

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Drake

While visiting Drake, you might make a stop by sights like Knapp Center and La Casa Cultural Center.

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Southwestern Hills

Though Southwestern Hills may not have many top sights, you can venture to the surrounding area to see attractions like Gray’s Lake Park and Lauridsen Amphitheater.

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Top Greater South Side Hotel Reviews

Days Inn & Suites by Wyndham Des Moines Airport

8/10 Good

"Clean room. Friendly staff and easy parking."

La Quinta by Wyndham Altoona Des Moines

10/10 Excellent

"Our room was a nice size. I especially liked the bed and pillows. Everything in our room was spon on. There was a floor drain somewhere before you walk into the pool. It just needs water poured down it because it stinks. Also! The information on the back of the door states check out time is noon. The front desk shows it's 11. I was here not too long ago and they weren't aware the times were different. They need to change the signs in the rooms! The pool was small and a bit chilly. After we left, they called us to let us know I had left my makeup mirror there and we went and picked it up. I really appreciated that. We'll be back"

Des Lux Hotel

10/10 Excellent

"Staff was great, we really appreciated the gift card for 801 Chophouse when we mentioned we were going there for our anniversary dinner. The only issue with the room was that there was shampoo or soap on the shower floor, when I stepped in. I slipped and almost fell. The room is very noisy Also, please get a better quality toilet paper. "

Holiday Inn Downtown - Mercy Area by IHG

8/10 Good

"All the staff were helpful and friendly, the room was clean and the beds were comfortable. There were 3 reasons we gave 4 instead of 5 on the overall rating: 1) the "free breakfast" was only extended to 2 adults from each room, and we had 4 adults in our room. So rather than eat in the hotel restaurant, we went to a local favorite brunch place, to cater to the wishes of the group, so that 'amenity' was wasted on us. 2) we had trouble figuring out how to get to the hotel because of the parking lot being closed. We did eventually locate the correct lot and were able to schlepp our luggage across the street safely, with some extra effort. 3) the faucet in the tub/shower was almost impossible to turn fully off. All 4 adult members of our party tried to turn the tub faucet so the water would fully STOP, but only the heavily muscled, 21-year old college athlete member of our party was able to get it turned fully off with great effort. I definitely want to repeat that ALL the staff were friendly and helpful, from Ken at the desk, to the wonderful bartender/waitress in Cityscape the night we arrived, to the housekeeping staff. Overall, it was a GOOD stay, with a few inconveniences."

Frequently asked questions

What's it like in Greater South Side?

Travellers are sure to enjoy a stay in Des Moines's Greater South Side neighbourhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.

What's the best accommodation in Greater South Side?

Based on our traveller data, Days Inn & Suites by Wyndham Des Moines Airport is one of the top choices for your stay in Greater South Side. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the neighbourhood include AmericInn by Wyndham Des Moines Airport and Hampton Inn Des Moines-Airport.

How many hotels can I expect to find in Greater South Side?

With 19 Expedia hotels and other accommodation options in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.

If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?

Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Greater South Side.

What is there to do around this Des Moines neighbourhood?

Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.

Hotels in Greater South Side

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Our top choices for Greater South Side hotels

Days Inn & Suites by Wyndham Des Moines Airport

Hampton Inn Des Moines-Airport

Quality Inn & Suites Des Moines Airport

AmericInn by Wyndham Des Moines Airport

Holiday Inn Des Moines-Airport/Conf Center by IHG

Hampton Inn & Suites Altoona-Des Moines

GrandStay Hotel & Suites

Baymont by Wyndham Des Moines Airport

Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

Fairfield Inn and Suites by Marriott Des Moines West

Quality Inn Indianola

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

Wildwood Lodge

Home2 Suites by Hilton Des Moines at Drake University

Country Inn & Suites by Radisson, Indianola, IA

Fairfield Inn & Suites by Marriott® Norwalk Des Moines

Home2 Suites By Hilton Altoona Des Moines

Homewood Suites by Hilton Des Moines Airport

Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

Drury Inn & Suites West Des Moines

Where to stay in Greater South Side

Downtown Des Moines

Historic East Village

Court District

Drake

Southwestern Hills

Top Greater South Side Hotel Reviews

Days Inn & Suites by Wyndham Des Moines Airport

Frequently asked questions

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